Hugh Hiu Nam Chan
Assistant Professor at Cleveland Clinic Lerner College of Medicine- Claim this Profile
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Cantonese Native or bilingual proficiency
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English Full professional proficiency
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Mandarin Full professional proficiency
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Bio
Experience
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Cleveland Clinic Lerner College of Medicine
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United States
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Higher Education
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100 - 200 Employee
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Assistant Professor
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Feb 2022 - Present
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Instructor
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May 2019 - Feb 2022
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Cleveland Clinic
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United States
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Hospitals and Health Care
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700 & Above Employee
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Research Associate
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Jun 2018 - Present
• With my creativity, I successfully set up a new neurological model, traumatic brain injury, in rodent, extending the research work to a new area. • With my long-term strategic planning skill, I assisted to the PI to apply two R01 grants; one was funded and one is pending.
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Postdoctoral Fellow
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Aug 2013 - Jun 2018
• Research and development of deep brain stimulation for stroke treatment.• Successfully revealed the possible underlying mechanisms, including the synaptogenesis, anti-inflammation and neurogenesis of the cerebellar stimulation mediated recovery effect.• Successfully obtain some pilot grants.
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Takeda
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Biotechnology
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1 - 100 Employee
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Research Scientist
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Sep 2011 - May 2013
• Screened the therapeutic effect of 50 small molecules, validated 20 different therapeutic targets for treatment of neurological diseases and set up different in vivo and ex vivo essays for drug screening. • Set up the in vivo ECG screening for cardiological side-effect of testing compounds. • Screened the therapeutic effect of 50 small molecules, validated 20 different therapeutic targets for treatment of neurological diseases and set up different in vivo and ex vivo essays for drug screening. • Set up the in vivo ECG screening for cardiological side-effect of testing compounds.
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Postdoctoral Fellow
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Oct 2009 - Sep 2011
• Confirmed the anti-Parkinsonian effect of two small molecules. • Successfully revealed the monoamine oxidase B inhibitory property of one of those molecule. • Initiating the communication with pharmaceuticals for industrial collaboration. • Confirmed the anti-Parkinsonian effect of two small molecules. • Successfully revealed the monoamine oxidase B inhibitory property of one of those molecule. • Initiating the communication with pharmaceuticals for industrial collaboration.
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Imperial College London
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Research Services
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700 & Above Employee
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PhD
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2005 - 2009
Therapeutic development of Parkinson's disease Therapeutic development of Parkinson's disease
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HKUST
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Hong Kong
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Education Administration Programs
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1 - 100 Employee
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Research Assistant
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2004 - 2005
• Revealed the inhibitory effect of 1 compound on neuronal NOS and confirm its neuroprotective effect in excitotoxic models. • Uncovered the AKT related signalling pathway as the underlying mechanism of neuroprotection. • Revealed the inhibitory effect of 1 compound on neuronal NOS and confirm its neuroprotective effect in excitotoxic models. • Uncovered the AKT related signalling pathway as the underlying mechanism of neuroprotection.
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Education
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Imperial College London
PhD, Neuroscience -
The Hong Kong University of Science and Technology
MPhil, Biochemistry