Experience

OmniAb, Inc.

• United States
• Biotechnology Research
• 1 - 100 Employee

• Sr. Research Scientist

  • Feb 2023 - Present



3T Biosciences

• United States
• Biotechnology Research
• 1 - 100 Employee

• Sr. Scientist II

  • Dec 2021 - Oct 2022

  Development for TCR-mimic protein therapeutics to enable safer bispecific antibodies. Development of platform technology Development for TCR-mimic protein therapeutics to enable safer bispecific antibodies. Development of platform technology



Gritstone bio

• United States
• Biotechnology Research
• 100 - 200 Employee

• Sr. Scientist

  • May 2019 - Nov 2021

  Development of TCR-mimic bispecific antibodies targeting tumor-specific peptide-HLA (human leukocyte antigen) complex - Lead pMHC-specific antibody development project (pMHC library construction for affinity maturation) - Collaborate with cross-functional teams (cell-based analysis and product development groups) Development of TCR-mimic bispecific antibodies targeting tumor-specific peptide-HLA (human leukocyte antigen) complex - Lead pMHC-specific antibody development project (pMHC library construction for affinity maturation) - Collaborate with cross-functional teams (cell-based analysis and product development groups)



Henlius USA Inc.

• United States
• Biotechnology Research
• 1 - 100 Employee

• Sr. Scientist

  • Dec 2017 - May 2019

  - Project leader for bispecific antibody development. - Single domain antibody (VHH) development - Project leader for bispecific antibody development. - Single domain antibody (VHH) development



Roche

• Switzerland
• Biotechnology Research
• 700 & Above Employee

• Scientist

  • Jan 2016 - Jul 2017

  * Rabbit monoclonal antibody development for tissue diagnostics using phage display. * Development of rabbit monoclonal antibody using dual host vector capable of expressing whole IgG in mammalian cells and expressing Fab in E. coli. * Rabbit monoclonal antibody development for tissue diagnostics using phage display. * Development of rabbit monoclonal antibody using dual host vector capable of expressing whole IgG in mammalian cells and expressing Fab in E. coli.



Biocare Medical

• United States
• Biotechnology Research
• 100 - 200 Employee

• Sr. Scientist

  • Sep 2012 - Jan 2016

  * Rabbit monoclonal antibodies development; • Phage/mammalian cell display • Chimeric antibody production • Hybridoma Technologies • Antibody library construction • Cloning and sequencing of the VH and VL from hybridoma • High-throughput single B cell cloning • PBMC activation for antibody production • Antibody production using WAVE bioreactor (fed-batch culture) • Development of Human papillomavirus (HPV) detection system… Show more * Rabbit monoclonal antibodies development; • Phage/mammalian cell display • Chimeric antibody production • Hybridoma Technologies • Antibody library construction • Cloning and sequencing of the VH and VL from hybridoma • High-throughput single B cell cloning • PBMC activation for antibody production • Antibody production using WAVE bioreactor (fed-batch culture) • Development of Human papillomavirus (HPV) detection system using in situ hybridization Show less * Rabbit monoclonal antibodies development; • Phage/mammalian cell display • Chimeric antibody production • Hybridoma Technologies • Antibody library construction • Cloning and sequencing of the VH and VL from hybridoma • High-throughput single B cell cloning • PBMC activation for antibody production • Antibody production using WAVE bioreactor (fed-batch culture) • Development of Human papillomavirus (HPV) detection system… Show more * Rabbit monoclonal antibodies development; • Phage/mammalian cell display • Chimeric antibody production • Hybridoma Technologies • Antibody library construction • Cloning and sequencing of the VH and VL from hybridoma • High-throughput single B cell cloning • PBMC activation for antibody production • Antibody production using WAVE bioreactor (fed-batch culture) • Development of Human papillomavirus (HPV) detection system using in situ hybridization Show less



Stanford University

• United States
• Higher Education
• 700 & Above Employee

• Basic Life Science Research Associate

  • Nov 2011 - Sep 2012

  * Studied the mechanism of action of Intravenous Immunoglobulin (IVIG) as a treatment of human leukocyte antigen (HLA)-sensitized transplantation patients. • Purification of HLA antibodies from patient serum and characterization using Luminex * Studied the mechanism of action of Intravenous Immunoglobulin (IVIG) as a treatment of human leukocyte antigen (HLA)-sensitized transplantation patients. • Purification of HLA antibodies from patient serum and characterization using Luminex



The National Institutes of Health

• United States
• Biotechnology Research
• 700 & Above Employee

• Research Fellow

  • Jul 2008 - Apr 2011

  * Human monoclonal antibody targeting Glypican 3 (GPC3) for liver cancer therapy • Production and purification of human GPC3 protein in mammalian cell • Establishment of stable cell line for GPC3 • Identification of scFv for heparin sulfate on GPC3 using phage display • Antibody production • Functional study of the antibody in vivo and in vitro * Immunotherapy for mesothelioma using immunocytokine and immunotoxin • Development of… Show more * Human monoclonal antibody targeting Glypican 3 (GPC3) for liver cancer therapy • Production and purification of human GPC3 protein in mammalian cell • Establishment of stable cell line for GPC3 • Identification of scFv for heparin sulfate on GPC3 using phage display • Antibody production • Functional study of the antibody in vivo and in vitro * Immunotherapy for mesothelioma using immunocytokine and immunotoxin • Development of an immunocytokine, IL2-SS1scFv, for targeted immunotherapy of mesothelioma * Technology development for antibody discovery • Mammalian cell display using Flp-In system • High-throughput hybridoma screening using ELISA and Guava Easycyte plus system

• Research Fellow

  • Mar 2007 - Jun 2008

  * Role of the epithelial cell transforming sequence 2 (ECT2) oncogene in tumor development • Identification of signaling pathway of ECT2 in lung cancer cell line using microarray • Establishment of ECT2 silencing cell lines using lentivirus-driven shRNA • Screening genes related to cytokinesis using shRNA library

• Visiting Fellow

  • Apr 2003 - Feb 2007

  * Differential gene expression associated with achaete-scute homologue-1 (hASH1) in a mouse neuroendocrine lung cancer model. • Global gene analysis in a neuroendocrine lung cancer mouse model