Hsiu-Wen (Irene) Tsai

Director, Histology at Champions Oncology, Inc.
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Contact Information
us****@****om
(386) 825-5501
Location
Rockville, Maryland, United States, US

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Experience

    • United States
    • Biotechnology
    • 100 - 200 Employee
    • Director, Histology
      • Dec 2021 - Present

      United States

    • Subject Matter Expert
      • Mar 2021 - Dec 2021

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Fellow
      • Aug 2018 - Mar 2021

      Baltimore, Maryland Area * Explore immunologic and metabolic mechanisms promoting laryngotracheal inflammation, airway wall remodeling, and fibrosis to develop new therapeutic strategies for airway diseases. * Collect fibrosis scar from patients with iatrogenic laryngotracheal stenosis to analyze the cell subtypes by means of flow cytometry and single-cell RNA seq analysis. * Obtain fibrosis samples from patients with iatrogenic laryngotracheal stenosis to develop primary cell culture (fibroblasts and… Show more * Explore immunologic and metabolic mechanisms promoting laryngotracheal inflammation, airway wall remodeling, and fibrosis to develop new therapeutic strategies for airway diseases. * Collect fibrosis scar from patients with iatrogenic laryngotracheal stenosis to analyze the cell subtypes by means of flow cytometry and single-cell RNA seq analysis. * Obtain fibrosis samples from patients with iatrogenic laryngotracheal stenosis to develop primary cell culture (fibroblasts and epithelial cells) for in vitro assay. * Focus on airway epithelial stem cell differentiation and function test, including trans-membrane electrical resistance measurement, permeability test, and interactions with fibroblasts. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Fellow
      • May 2013 - Apr 2017

      Gainesville, Florida Area * Set up multi-channel electrode arrays to record neurons in the brainstem of small animals to map the interconnections of respiratory-related neurons during a swallow, airway obstruction, and breathing. * Assisted with the development of an internal airway percussion medical device to increase the concentration of exhaled protein in humans and canines for the future diagnosis of pulmonary diseases. * Collaborated with a clinical physician for the measurement of cough ability in… Show more * Set up multi-channel electrode arrays to record neurons in the brainstem of small animals to map the interconnections of respiratory-related neurons during a swallow, airway obstruction, and breathing. * Assisted with the development of an internal airway percussion medical device to increase the concentration of exhaled protein in humans and canines for the future diagnosis of pulmonary diseases. * Collaborated with a clinical physician for the measurement of cough ability in elderly patients with non-tuberculous mycobacteria (NTM) infections. Demonstrated patients with NTM had defect cough ability that might cause lung infections.

    • Graduate Research Assistant
      • Aug 2008 - May 2013

    • Staff Scientist
      • Oct 2007 - Jul 2008

      Hsinchu City, Taiwan * Developed and tested the safety and purity of new drugs for the treatment of cough. * Followed the USP to test the drug’s purity and stability. Analyzed the data and summarized the data for quality control.

    • Taiwan
    • Medical Practices
    • 300 - 400 Employee
    • Research Assistant
      • Dec 2004 - Sep 2007

      * Demonstrated transient limb ischemia and simvastatin increase the expression of heme-oxygenase-1 to protect the liver from ischemia-reperfusion injury

Education

  • University of Florida
    Doctor of Philosophy - PhD, Physiological Sciences
    2008 - 2013
  • National Cheng Kung University
    Master's degree, Biochemistry, Biophysics and Molecular Biology
    2002 - 2004

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