Howard Rosenzweig

Instructor at Oakton Community College
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Contact Information
us****@****om
(386) 825-5501
Location
Skokie, Illinois, United States, US

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Larry Chapoy

Howard was a very creative scientist in our group. He would come up with innovative solutions to chemical syntheses problems. He was a little non-conformist and fun to be around.Someone looking for these traits would be well served with Howard. Larry Chapoy

Michael Quinn

Dr. Rosenzweig has a solid foundation in organic chemistry. He used this background to continually provide innovative solutions in approaching his projects. In addition, he fully integrated himself with his co-workers to participate with successful product development teams. He was a resoected member of a productdveopment team.

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Experience

    • United States
    • Higher Education
    • 500 - 600 Employee
    • Instructor
      • Jan 2004 - Dec 2022

      Lecturing undergraduate organic chemistry and labs, as well as tutoring organic/general chemistry at their Learning Center. Lecturing undergraduate organic chemistry and labs, as well as tutoring organic/general chemistry at their Learning Center.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Visiting Research Specialist
      • Aug 2005 - Dec 2005

      Performed LC/MS – MS pharmacology analysis as part of work for a GLP laboratory at UIC. Performed LC/MS – MS pharmacology analysis as part of work for a GLP laboratory at UIC.

    • Chemistry Instructor
      • Jan 2003 - May 2003

      Prepared and presented lectures and exams for Introductory Chemistry for students in the Nursing Program. Prepared and presented lectures and exams for Introductory Chemistry for students in the Nursing Program.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Senior Research Associate
      • Sep 2001 - Mar 2002

      Investigated the synthesis and study of new nanostructured materials for potential molecular electronic and optical devices, as well as inventing a potential strategy for introducing various chromophores of interest into nanorod-type environments. Work involved synthesis of perylene derivatives as well as a new class of cationic phospholipid. Investigated the synthesis and study of new nanostructured materials for potential molecular electronic and optical devices, as well as inventing a potential strategy for introducing various chromophores of interest into nanorod-type environments. Work involved synthesis of perylene derivatives as well as a new class of cationic phospholipid.

    • Senior Scientist
      • Jan 1998 - Dec 2000

      Contributed significantly to the development of novel materials (e.g. silicone-hydrogel hybrids) for extended wear (30 day) contact lenses, for which a patent has been granted. These materials display excellent oxygen permeability and water content. Work involved polymer synthesis and characterization as well as investigation of various surface modification methods, either through the formulation itself , or through subsequent chemical modification after lens formation. Synthesis of novel… Show more Contributed significantly to the development of novel materials (e.g. silicone-hydrogel hybrids) for extended wear (30 day) contact lenses, for which a patent has been granted. These materials display excellent oxygen permeability and water content. Work involved polymer synthesis and characterization as well as investigation of various surface modification methods, either through the formulation itself , or through subsequent chemical modification after lens formation. Synthesis of novel monomers of my own design were also performed. Invented a novel method to significantly lower lysozyme binding to hydrogel surfaces as well. Show less Contributed significantly to the development of novel materials (e.g. silicone-hydrogel hybrids) for extended wear (30 day) contact lenses, for which a patent has been granted. These materials display excellent oxygen permeability and water content. Work involved polymer synthesis and characterization as well as investigation of various surface modification methods, either through the formulation itself , or through subsequent chemical modification after lens formation. Synthesis of novel… Show more Contributed significantly to the development of novel materials (e.g. silicone-hydrogel hybrids) for extended wear (30 day) contact lenses, for which a patent has been granted. These materials display excellent oxygen permeability and water content. Work involved polymer synthesis and characterization as well as investigation of various surface modification methods, either through the formulation itself , or through subsequent chemical modification after lens formation. Synthesis of novel monomers of my own design were also performed. Invented a novel method to significantly lower lysozyme binding to hydrogel surfaces as well. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Associate
      • Oct 1995 - Oct 1997

      Had invented a new class of synthetic transfection reagent, as well as performing the chemical modification of natural and unnatural phospholipids to produce another class of cationic lipid, from which we’ve obtained structure-activity relationships with regard to these various cationic amphiphiles' ability to transfect DNA into mammalian cells. This class of cationic phospholipid is significant in that it has the potential to be used for systemic gene therapy, due to the stability of its… Show more Had invented a new class of synthetic transfection reagent, as well as performing the chemical modification of natural and unnatural phospholipids to produce another class of cationic lipid, from which we’ve obtained structure-activity relationships with regard to these various cationic amphiphiles' ability to transfect DNA into mammalian cells. This class of cationic phospholipid is significant in that it has the potential to be used for systemic gene therapy, due to the stability of its DNA-lipid complex in serum.

    • Postdoctoral Research Associate
      • Sep 1994 - Oct 1995

      Studied interprotein electron transfer (e.g. Cytochrome C Peroxidase and Cytochrome C) via Nd:YAG laser flash photolysis of luminescent derivatives (e.g. Zn - Porphyrin substituted) coupled with transient absorption spectroscopy, to gain insight into the mechanism of physiologically relevant electron transfer processes. Work involved enzyme isolation and modification, as well as the above kinetic study.

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Senior Research Scientist
      • Jul 1992 - Mar 1994

      Invented a novel, non-chromatographic methodology for purification of 99mTc-labeled monoclonal antibodies (MAbs). A new method for boronation of an MAb for potential boron neutron capture therapy (BNCT) had also been developed. 99mTc-labeling of an MAb through its oligosaccharide residues has been performed. Also, development of novel targeting methods for delivering radiosensitizers to neoplastic tissue were investigated, such as through the synthesis of a 2-nitroimidazole-polyamine… Show more Invented a novel, non-chromatographic methodology for purification of 99mTc-labeled monoclonal antibodies (MAbs). A new method for boronation of an MAb for potential boron neutron capture therapy (BNCT) had also been developed. 99mTc-labeling of an MAb through its oligosaccharide residues has been performed. Also, development of novel targeting methods for delivering radiosensitizers to neoplastic tissue were investigated, such as through the synthesis of a 2-nitroimidazole-polyamine derivative. Used submarine agarose electrophoresis of DNA for studying Drug-Topoisomerase I/II interactions. Show less Invented a novel, non-chromatographic methodology for purification of 99mTc-labeled monoclonal antibodies (MAbs). A new method for boronation of an MAb for potential boron neutron capture therapy (BNCT) had also been developed. 99mTc-labeling of an MAb through its oligosaccharide residues has been performed. Also, development of novel targeting methods for delivering radiosensitizers to neoplastic tissue were investigated, such as through the synthesis of a 2-nitroimidazole-polyamine… Show more Invented a novel, non-chromatographic methodology for purification of 99mTc-labeled monoclonal antibodies (MAbs). A new method for boronation of an MAb for potential boron neutron capture therapy (BNCT) had also been developed. 99mTc-labeling of an MAb through its oligosaccharide residues has been performed. Also, development of novel targeting methods for delivering radiosensitizers to neoplastic tissue were investigated, such as through the synthesis of a 2-nitroimidazole-polyamine derivative. Used submarine agarose electrophoresis of DNA for studying Drug-Topoisomerase I/II interactions. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Instructor
      • May 1989 - Jul 1992

      Invented a novel, non-chromatographic methodology for purification of 99mTc-labeled monoclonal antibodies (MAbs). A new method for boronation of an MAb for potential boron neutron capture therapy (BNCT) had also been developed. 99mTc-labeling of an MAb through its oligosaccharide residues has been performed. Also, development of novel targeting methods for delivering radiosensitizers to neoplastic tissue were investigated, such as through the synthesis of a 2-nitroimidazole-polyamine… Show more Invented a novel, non-chromatographic methodology for purification of 99mTc-labeled monoclonal antibodies (MAbs). A new method for boronation of an MAb for potential boron neutron capture therapy (BNCT) had also been developed. 99mTc-labeling of an MAb through its oligosaccharide residues has been performed. Also, development of novel targeting methods for delivering radiosensitizers to neoplastic tissue were investigated, such as through the synthesis of a 2-nitroimidazole-polyamine derivative. Have learned and utilized various biochemical techniques such as gel filtration, ultrafiltration, ultracentrifugation, SDS-PAGE and IEF (PhastSystem), HPLC (reverse phase, gel filtration, ion exchange) and FPLC for various aspects of the above-mentioned work, as well as using submarine agarose electrophoresis of DNA for studying Drug-Topoisomerase I/II interactions. Basic techniques in cell culture had also been learned.

    • Postdoctoral Research Associate
      • Jul 1988 - Apr 1989

      Involved in collaborative work in which we showed that a macrocyclic artificial receptor designed for recognition of thymidine could also inhibit the flavin-mediated photooxidation of 1,4 butanedithiol. Work involved synthesis of various heterocycles

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Research Associate
      • Jan 1988 - Jun 1988

      Involved in collaborative work in which we showed that a macrocyclic artificial receptor designed for recognition of thymidine could also inhibit the flavin-mediated photooxidation of 1,4 butanedithiol. Work involved synthesis of various heterocycles Involved in collaborative work in which we showed that a macrocyclic artificial receptor designed for recognition of thymidine could also inhibit the flavin-mediated photooxidation of 1,4 butanedithiol. Work involved synthesis of various heterocycles

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Research Associate
      • Apr 1985 - Oct 1987

      Conceived and developed the key-step for producing cyclic, cis-vicinal tertiary diamines, a process for which a patent has been granted. Developed proficiency in various organometallic synthetic techniques, such as in the use of Schlenckware, vacuum lines and inert atmosphere dry boxes for manipulation of oxygen and moisture-sensitive compounds. Operated WM-300 and MSL-300 F.T. NMRs for characterization and variable temperature experiments; IR, UV-VIS, as well as utilizing analytical and… Show more Conceived and developed the key-step for producing cyclic, cis-vicinal tertiary diamines, a process for which a patent has been granted. Developed proficiency in various organometallic synthetic techniques, such as in the use of Schlenckware, vacuum lines and inert atmosphere dry boxes for manipulation of oxygen and moisture-sensitive compounds. Operated WM-300 and MSL-300 F.T. NMRs for characterization and variable temperature experiments; IR, UV-VIS, as well as utilizing analytical and preparative GC. Show less Conceived and developed the key-step for producing cyclic, cis-vicinal tertiary diamines, a process for which a patent has been granted. Developed proficiency in various organometallic synthetic techniques, such as in the use of Schlenckware, vacuum lines and inert atmosphere dry boxes for manipulation of oxygen and moisture-sensitive compounds. Operated WM-300 and MSL-300 F.T. NMRs for characterization and variable temperature experiments; IR, UV-VIS, as well as utilizing analytical and… Show more Conceived and developed the key-step for producing cyclic, cis-vicinal tertiary diamines, a process for which a patent has been granted. Developed proficiency in various organometallic synthetic techniques, such as in the use of Schlenckware, vacuum lines and inert atmosphere dry boxes for manipulation of oxygen and moisture-sensitive compounds. Operated WM-300 and MSL-300 F.T. NMRs for characterization and variable temperature experiments; IR, UV-VIS, as well as utilizing analytical and preparative GC. Show less

Education

  • The Ohio State University
    Ph.D., Organic Chemistry
    1981 - 1987
  • SUNY Stony Brook
    B.S., Chemistry
    1979 - 1981
  • SUNY Farmingdale
    A.S., Chemistry
    1977 - 1979
  • Plainedge High School

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