Henk van Wyk

Chief Scientist at Reven Pharmaceuticals
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Contact Information
us****@****om
(386) 825-5501
Location
Denver Metropolitan Area

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Chief Scientist
      • Oct 2019 - Present

      Golden, Colorado, United States Over the last year we have engaged in studies of new roles to affect mitochondrial energy production, particularly the coupling in the redox pathway. The age related inflammatory responses in diseases, including Alzheimer’s disease, Parkinson's disease, atherosclerosis, and cancer. Mitochondrial dysfunction is important in these conditions, suggesting a pivotal role for mitochondria in the coordination of pro-inflammatory signaling from the cytosol. It is now clear that reactive oxygen species… Show more Over the last year we have engaged in studies of new roles to affect mitochondrial energy production, particularly the coupling in the redox pathway. The age related inflammatory responses in diseases, including Alzheimer’s disease, Parkinson's disease, atherosclerosis, and cancer. Mitochondrial dysfunction is important in these conditions, suggesting a pivotal role for mitochondria in the coordination of pro-inflammatory signaling from the cytosol. It is now clear that reactive oxygen species are the signals that can trigger the assembly and successive activation of caspase-1- activating complexes known as inflammasomes. Our formulations can antagonise these effects as shown in our clinical research results.

    • Q A Manager
      • Apr 2014 - Oct 2019

Education

  • Univ of Northwest Potch Campus
    Master's Degree, Pharmacology and Toxicology
    1998 - 2010

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