Haley Grimm
Virtual Lab Manager at HappiLabs- Claim this Profile
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Bio
Experience
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HappiLabs
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United States
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Research
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1 - 100 Employee
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Virtual Lab Manager
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Oct 2019 - Present
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Horne Lab
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University of Pittsburgh
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Graduate Researcher
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Jan 2015 - Sep 2019
My work in the Horne Lab investigates peptides and other bio-inspired oligomers as piezoelectrics with the goal of gaining a better understanding soft, organic piezoelectrics. Thus far, my work has focused initially on helical α-peptides, peptoids, and aromatic oligoamides to investigate how conformational rigidity effect piezoelectric behavior. Ongoing work is investigating peptide and protein surface structure and activity. Technical skills include solid phase peptide synthesis, small molecule organic synthesis, HPLC, MALDI-TOF, CD, AFM, XPS, Contact Angle, DART-PFM, UV and fluorescence based assays. Reference: Interplay among Sequence, Folding Propensity, and Bio-Piezoelectric Response in Short Peptides and Peptoids. Christopher W. Marvin, Haley M. Grimm, Nathaniel C. Miller, W. Seth Horne, and Geoffrey R. Hutchison. The Journal of Physical Chemistry B 2017 121 (44), 10269-10275 DOI: 10.1021/acs.jpcb.7b10085 Show less
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The Reczek Group
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Denison University
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Undergraduate Researcher
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Jan 2012 - May 2014
During my time in the Reczek Group I worked to optimize a synthetic pathway affording a variety of core-substituted naphthalene diimide (cNDI) derivatives. A novel method to characterize the products generated in the initial bromination step was published, along with a microwave protocol for the subsequent imidization step. The alterations and new findings in regards to these steps led to the attainment of optimal yields for these reactions and overall shorter reaction times. cNDI derivatives show potential as useful components in donor-acceptor columnar liquid crystals (DACLCs). Reference: Thompson, A. C., et al. (2015). "Efficient Bromination of Naphthalene Dianhydride and Microwave-Assisted Synthesis of Core-Brominated Naphthalene Diimides." Synthetic Communications 45(9): 1127-1136. Show less
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Education
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University of Pittsburgh
Doctor of Philosophy (Ph.D.), Bio-organic Chemistry -
Denison University
Bachelor of Science (B.S.), Chemistry -
Hopewell High School