Gretchen Guaglianone

Scientist at Encodia, Inc.
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Contact Information
Location
Irvine, California, United States, US

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Experience

    • Information Technology & Services
    • 1 - 100 Employee
    • Scientist
      • Jul 2022 - Present
    • United States
    • Higher Education
    • 1 - 100 Employee
    • UCI Mass Spectrometry Innovation Fellow
      • Sep 2020 - Jul 2022

      • Selected from all UCI chemistry graduate students to work in the mass spectrometry core facility that serves 24 departments across UCI and 5 additional UC universities • Ran over 10,000 samples for high resolution mass confirmation ranging from small molecules to peptides, oligonucleotides, MOFs, polymers, and proteins • Pioneered the use of native IMS-MS and MALDI imaging for research on Aβ and related peptides to further Alzheimer’s disease research at UCI • Assisted in instrument selection, method development, and troubleshooting with graduate students and industry professionals running unique molecules Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • PhD, Chemistry- Nowick Laboratory
      • Sep 2017 - Jul 2022

      • Pioneered the application of fluorescence microscopy and ion mobility mass spectrometry in the Nowick laboratory to study the solution phase assembly and cellular interactions of Aβ derived peptides • Communicated my scientific results and research progress in 9 scientific publications, and at 6 regional and national scientific conferences to multidisciplinary audiences • Independently planned, managed, and executed 3 projects under strict funding timelines to meet deliverables, provided regular group updates through presentations and written reports • Optimized the groups’ workflow by maintaining, troubleshooting, and developing methods for 6 preparative and analytical HPLCs over 4 years to serve 13 graduate students Show less

    • Future Leaders Associate, GMS Quality-Analytical Scientist
      • Aug 2016 - Aug 2017

      • Winner of GSK R&D Hack-a-thon for innovations in Data Science • Facilitated Community of Practice meetings between global sites to share learnings and methods of pharmacopeia compliance • Revitalized Analytical Workshop presentations to promote discussion of current topics and concerns within the analytical community • Supported the Contamination Review Board on key decisions in batch release following foreign particle incidents • Analyzed forced degradation of the herpes and Augmentin profiles • Assisted in the evaluation of new Raman Spectroscopy technology for incorporation into GMP workflow Show less

    • Pharmaceutical Manufacturing
    • 200 - 300 Employee
    • Analytical Support Intern, Quality Control
      • Jun 2015 - Sep 2015

      • Developed Reagents Database containing all reagents necessary for procedural testing • Assigned expiry information to existing reagents per auditor request • Participated in maintenance of High pH Anion-Exchange Chromatography with Pulsed Amperometric Detection instrument • Knowledgable in LIMS, good manufacturing practices, and aseptic technique • Developed Reagents Database containing all reagents necessary for procedural testing • Assigned expiry information to existing reagents per auditor request • Participated in maintenance of High pH Anion-Exchange Chromatography with Pulsed Amperometric Detection instrument • Knowledgable in LIMS, good manufacturing practices, and aseptic technique

    • United States
    • Medical Device
    • 1 - 100 Employee
    • Clinical Project Assistant
      • Jun 2014 - Sep 2014

      • Prepared for new study by obtaining required regulatory approvals for protocols and amendments and assembling necessary medical documents for physicians, patients and research associates • Reconciled Trial Master Files and adverse events to comply with regulatory requirements • Identified targeted companies and supplied them with information regarding Clinlogix for potential business opportunities • Assisted in editing clinical trial proposals • Prepared for new study by obtaining required regulatory approvals for protocols and amendments and assembling necessary medical documents for physicians, patients and research associates • Reconciled Trial Master Files and adverse events to comply with regulatory requirements • Identified targeted companies and supplied them with information regarding Clinlogix for potential business opportunities • Assisted in editing clinical trial proposals

Education

  • UC Irvine
    Doctor of Philosophy - PhD, Chemistry
    2017 - 2022
  • University of California, Los Angeles
    Bachelor of Science (B.S.), Chemistry
    2012 - 2016

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