Gretchen Guaglianone
Scientist at Encodia, Inc.- Claim this Profile
Click to upgrade to our gold package
for the full feature experience.
Topline Score
Bio
Experience
-
Encodia, Inc.
-
Information Technology & Services
-
1 - 100 Employee
-
Scientist
-
Jul 2022 - Present
-
-
-
UC Irvine Department of Chemistry
-
United States
-
Higher Education
-
1 - 100 Employee
-
UCI Mass Spectrometry Innovation Fellow
-
Sep 2020 - Jul 2022
• Selected from all UCI chemistry graduate students to work in the mass spectrometry core facility that serves 24 departments across UCI and 5 additional UC universities • Ran over 10,000 samples for high resolution mass confirmation ranging from small molecules to peptides, oligonucleotides, MOFs, polymers, and proteins • Pioneered the use of native IMS-MS and MALDI imaging for research on Aβ and related peptides to further Alzheimer’s disease research at UCI • Assisted in instrument selection, method development, and troubleshooting with graduate students and industry professionals running unique molecules Show less
-
-
-
UC Irvine
-
United States
-
Higher Education
-
700 & Above Employee
-
PhD, Chemistry- Nowick Laboratory
-
Sep 2017 - Jul 2022
• Pioneered the application of fluorescence microscopy and ion mobility mass spectrometry in the Nowick laboratory to study the solution phase assembly and cellular interactions of Aβ derived peptides • Communicated my scientific results and research progress in 9 scientific publications, and at 6 regional and national scientific conferences to multidisciplinary audiences • Independently planned, managed, and executed 3 projects under strict funding timelines to meet deliverables, provided regular group updates through presentations and written reports • Optimized the groups’ workflow by maintaining, troubleshooting, and developing methods for 6 preparative and analytical HPLCs over 4 years to serve 13 graduate students Show less
-
-
-
-
Future Leaders Associate, GMS Quality-Analytical Scientist
-
Aug 2016 - Aug 2017
• Winner of GSK R&D Hack-a-thon for innovations in Data Science • Facilitated Community of Practice meetings between global sites to share learnings and methods of pharmacopeia compliance • Revitalized Analytical Workshop presentations to promote discussion of current topics and concerns within the analytical community • Supported the Contamination Review Board on key decisions in batch release following foreign particle incidents • Analyzed forced degradation of the herpes and Augmentin profiles • Assisted in the evaluation of new Raman Spectroscopy technology for incorporation into GMP workflow Show less
-
-
-
Sanofi Pasteur
-
Pharmaceutical Manufacturing
-
200 - 300 Employee
-
Analytical Support Intern, Quality Control
-
Jun 2015 - Sep 2015
• Developed Reagents Database containing all reagents necessary for procedural testing • Assigned expiry information to existing reagents per auditor request • Participated in maintenance of High pH Anion-Exchange Chromatography with Pulsed Amperometric Detection instrument • Knowledgable in LIMS, good manufacturing practices, and aseptic technique • Developed Reagents Database containing all reagents necessary for procedural testing • Assigned expiry information to existing reagents per auditor request • Participated in maintenance of High pH Anion-Exchange Chromatography with Pulsed Amperometric Detection instrument • Knowledgable in LIMS, good manufacturing practices, and aseptic technique
-
-
-
Clinlogix
-
United States
-
Medical Device
-
1 - 100 Employee
-
Clinical Project Assistant
-
Jun 2014 - Sep 2014
• Prepared for new study by obtaining required regulatory approvals for protocols and amendments and assembling necessary medical documents for physicians, patients and research associates • Reconciled Trial Master Files and adverse events to comply with regulatory requirements • Identified targeted companies and supplied them with information regarding Clinlogix for potential business opportunities • Assisted in editing clinical trial proposals • Prepared for new study by obtaining required regulatory approvals for protocols and amendments and assembling necessary medical documents for physicians, patients and research associates • Reconciled Trial Master Files and adverse events to comply with regulatory requirements • Identified targeted companies and supplied them with information regarding Clinlogix for potential business opportunities • Assisted in editing clinical trial proposals
-
-
Education
-
UC Irvine
Doctor of Philosophy - PhD, Chemistry -
University of California, Los Angeles
Bachelor of Science (B.S.), Chemistry