Graham Speight

Executive Vice President of R&D and Operations at OXFORD GENE TECHNOLOGY LIMITED
  • Claim this Profile
Contact Information
Location
Greater Oxford Area, UK

Topline Score

Bio

Generated by
Topline AI

0

/5.0
/ Based on 0 ratings
  • (0)
  • (0)
  • (0)
  • (0)
  • (0)

Filter reviews by:

No reviews to display There are currently no reviews available.

0

/5.0
/ Based on 0 ratings
  • (0)
  • (0)
  • (0)
  • (0)
  • (0)

Filter reviews by:

No reviews to display There are currently no reviews available.
You need to have a working account to view this content. Click here to join now

Experience

    • United Kingdom
    • Research
    • 1 - 100 Employee
    • Executive Vice President of R&D and Operations
      • Dec 2021 - Present
    • United Kingdom
    • Research
    • 1 - 100 Employee
    • Executive Vice President R&D
      • Apr 2018 - Nov 2021

    • R&D Director
      • Jan 2014 - Mar 2018

      • Manage early stage research through to the delivery of novel RUO next generation sequencing (NGS) oncology products to global markets. Recently developed and launched; a 60 gene solid tumour, a 7 gene ovarian predictive panel and a 25 gene myeloid NGS panel. Currently developing a pipeline of multiple follow-on NGS products involving >100 genes in both solid tumours and haematological cancers.• Build and lead cross-functional project teams which consistently deliver to time and budget constraints.• Establish and maintain clinical collaborators.• Project managed and co-ordinated multiple TSB funded grants and part of an EU FP7 funded Pathogen sequencing project (PATHSEEK) developing an automated, user-friendly disruptive NGS platform for use in diagnostic microbiology, directly from clinical specimens. Show less

    • Director of Biomarker Development
      • Jan 2013 - Jan 2014

    • Head of Genomic Biomarkers
      • Nov 2009 - Jan 2013

      • Successfully in-licensed a set of epigenetic biomarkers for the early diagnosis of colorectal cancer. These markers were further developed for analytical and clinical validation in both faeces and plasma.• Established a collaboration with the ICR and jointly discovered and validated a set of miRNA markers for the diagnosis and prognosis of prostate cancer. This led to the filing of multiple patent applications. These markers were validated in fresh and FFPE tissue as well as plasma.

    • Head of Molecular Biology Group
      • Jan 2007 - Dec 2009

      • Led the molecular biology group consisting of up to 14 scientists, working on a number of internal R&D programmes, service projects and international grant funded consortia.• Established and managed the team responsible for delivering the outsourced Wellcome Trust Case Control Consortium (WTCCC) high throughput CNV programme, this involved developing the protocol which successfully processed >20,000 DNA samples on microarrays in 20 weeks.• Worked closely with business development, marketing and sales colleagues to secure further large scale service projects, including presenting data at trade fairs and scientific meetings Show less

    • Australia
    • Research Services
    • 400 - 500 Employee
    • Australian Cancer Research Foundation Facility Manager
      • Apr 2005 - Dec 2006

      • Ensured the efficient operation, financial viability, and public awareness of the Australian Cancer Research Foundation Unit for Molecular Genetics. • Responsible and accountable for the management of the facility including self-financing via cost recovery. • Involved in the strategic planning of the Oncology department’s clinical research, advising group leaders on how the unit could benefit their translational research. • Responsible for the development and application of novel technologies. Show less

    • Hong Kong
    • Computers and Electronics Manufacturing
    • Senior Scientist
      • 2002 - 2005

      • Successfully ran multi-disciplinary teams completing numerous target discovery projects, where my team were successful in cloning in excess of 150 GPCRs permitting transient and stable expression of selected receptors for drug screens for inflammatory diseases. • Successfully ran multi-disciplinary teams completing numerous target discovery projects, where my team were successful in cloning in excess of 150 GPCRs permitting transient and stable expression of selected receptors for drug screens for inflammatory diseases.

    • United Kingdom
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist
      • 2000 - 2002

      • Integral member of drug discovery projects working within multi-disciplinary teams. • Main responsibilities included the strategic planning, management and supervision of scientists. Successfully cloned and expressed a number of ion channels allowing identification of lead compounds. • Integral member of drug discovery projects working within multi-disciplinary teams. • Main responsibilities included the strategic planning, management and supervision of scientists. Successfully cloned and expressed a number of ion channels allowing identification of lead compounds.

Education

  • Univeristy of Wales College of Medicine
    PhD, Neuropsychiatric genetics
    1995 - 2000
  • University of Bath
    BSc. Hons., Biochemistry
    1991 - 1995

Community

You need to have a working account to view this content. Click here to join now