Giulio Lievore, PhD

at ChromaCon - A YMC Company
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Contact Information
us****@****om
(386) 825-5501
Location
Greater Zurich Area, CH
Languages
  • English Full professional proficiency
  • Italian Native or bilingual proficiency
  • Tedesco Limited working proficiency

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Credentials

  • Chemist Licence
    Università degli Studi di Ferrara
    Dec, 2020
    - Oct, 2024
  • Pharmacist Licence
    Università degli Studi di Ferrara
    Nov, 2018
    - Oct, 2024

Experience

  • ChromaCon - A YMC Company
    • Switzerland
    • Biotechnology Research
    • 1 - 100 Employee
      • Nov 2022 - Present

      • Sep 2021 - Oct 2022

      • Batch and continuous chromatographic processes development for the purifications (capture, polishing) of biopharmaceuticals (peptides, oligonucleotides, proteins).• Resin and method screening to increase throughput of oligonucleotide purifications;• Development of a recycling chromatographic method for the enrichment of a oligo product-related impurity for analytical characterization;

  • University of Ferrara
    • Research
    • 500 - 600 Employee
    • Doctoral Researcher
      • Nov 2019 - Oct 2022

      Analytical characterization and downstream processing of different kinds of biopharmaceutical compounds. • Investigation of innovative affinity resins and development of chromatography-based strategies for the preparative capture of recombinant proteins and mAbs; • Development of polishing steps via more techniques (IEX, RP, IP-RP, HIC, Mixed-mode) applied to peptides and oligonucleotides. • Chromatographic isolation and enrichment of product related impurities of a bioactive peptide for the accomplishment of analytical characterization release protocols; • Upstream crudes characterization: analytical method development and convalidation with techniques such as: UHPLC, LC-MS. Show less

  • ETH Zürich
    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Scientific Assistant
      • Jul 2019 - Oct 2019

      Investigation of innovative techniques for bioactive molecules isolation and purification. • In-depth study of continuous chromatography techniques (i.e. SMB, MCSGP, CaptureSMB) and their application to raw mixtures of peptides, mAbs, oligonucleotides. Investigation of innovative techniques for bioactive molecules isolation and purification. • In-depth study of continuous chromatography techniques (i.e. SMB, MCSGP, CaptureSMB) and their application to raw mixtures of peptides, mAbs, oligonucleotides.

    • Postgraduate Research Fellow
      • Sep 2018 - Jun 2019

      • This research project, carried out jointly with Fresenius Kabi iPSUM, aimed to develop a GMP downstream protocol for the polishing of a bioactive peptide. • Process-Analytical-Technology (PAT) implementation. • Characterization of adsorption equilibria of the raw and pure analyte on several stationary phases to model and optimize the purification process. • This research project, carried out jointly with Fresenius Kabi iPSUM, aimed to develop a GMP downstream protocol for the polishing of a bioactive peptide. • Process-Analytical-Technology (PAT) implementation. • Characterization of adsorption equilibria of the raw and pure analyte on several stationary phases to model and optimize the purification process.

Education

  • University of Ferrara
    PhD, Chemistry
    2019 - 2022
  • ETH Zürich
    Specialization course in "Continuous Chromatography for Biotherapeutics"
    2019 - 2019
  • University of Ferrara
    M. Sc. Pharmacy
    2013 - 2018

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