Experience

Venn Life Sciences - part of hVIVO plc

• United Kingdom
• Research
• 1 - 100 Employee

• SAS programmer

  • Nov 2018 - Present

  Breda Area, Netherlands



Home

• Freelance programmer and hardware consultancy

  • May 2018 - Present

  Oss, the Netherlands Work on some freelance programming and consumer pc hardware assignments



Backbone Works

• Netherlands
• IT Services and IT Consulting

• Trainee

  • Jan 2018 - Apr 2018

  Tilburg Area, Netherlands Followed a course to become a full stack PHP and JS developer. Allthough (due to circumstances) I could not complete the course, I certainly gained some skills and got a good insight into the world of commercial software development.



Charles River Laboratories

• United States
• Biotechnology Research
• 700 & Above Employee

• Senior Laboratory Technician

  • 2016 - 2017

  's-Hertogenbosch Analyst at the department of In Vitro & Environmental Toxicology, in the Genetic toxicology section.



Acerta Pharma B.V. (A member of the AstraZeneca Group)

• Netherlands
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Scientist

  • 2015 - 2016

  Oss Responsible for testing the effect of compounds on the growth and viability of tumor cells using the MTT assay for quantification. . I also designed an automatic dataprocessing template, using visual basic for excel, with which the large amount of data generated could be processed in minutes instead of hours or even a day's work.



Merck

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• PK-PD Associate

  • 2011 - 2014

  Oss, The netherlands As Clinical PKPD Scientist I was responsible for the validation and processing of clinical and pre-clinical data sets for pharmacokinetic and pharmacodynamic modeling and PK datasets for NCA analyses, using SAS.



Schering Plough

• Senior Assistant Scientist B DMPK

  • 2005 - 2011

  Oss, The Netherlands - Development, validation and performance of in vitro ADME (Absorption, Distribution, Metabolism, and Excretion) assays involving intestinal permeability, phase I and II metabolism and plasma protein binding (PPB) of parent drugs. - Automation of in vitro ADME assays to robotic platforms such as TECAN- and Biomek- liquidhandlers. - Monitoring in vitro ADME dataflow using self designed Excel workbooks using VBA (visual basic for applications) to visualize… Show more - Development, validation and performance of in vitro ADME (Absorption, Distribution, Metabolism, and Excretion) assays involving intestinal permeability, phase I and II metabolism and plasma protein binding (PPB) of parent drugs. - Automation of in vitro ADME assays to robotic platforms such as TECAN- and Biomek- liquidhandlers. - Monitoring in vitro ADME dataflow using self designed Excel workbooks using VBA (visual basic for applications) to visualize possible trends or problems - Member of DMPK/Discovery Informatics team wich was responsible for: • Design and development of logistic applications to create a fully automated compound/assay- flow within the DMPK: from the request by the teams to the final data upload to the final database (AIMS, DMPK selection tool)) • Creating automated data processing workbooks within excel using VBA Maintenance of the Animals! Excel report tool. and when necessary development of extra features. - IT/Excel VBA knowledge base Show less



N.V. Organon

• Hospitals and Health Care
• 1 - 100 Employee

• Assistant Scientist Pharmacology

  • 2001 - 2004

  Oss, The Netherlands - Development and performance of in vitro assays to estimate oestrogenicity of Lead Finding and Lead optimization com-pounds, using breast- and endometrium- tumor cells. - Development and performance of in vitro assays for the in vitro osteoporosis group to be used for osteoprosis Lead Finding and LO (Lead optimization). - Assay biomarkers in samples from in house performed animal studies with LO compounds, using ELISA-, RIA-, and cell culturing techniques (in Vitro… Show more - Development and performance of in vitro assays to estimate oestrogenicity of Lead Finding and Lead optimization com-pounds, using breast- and endometrium- tumor cells. - Development and performance of in vitro assays for the in vitro osteoporosis group to be used for osteoprosis Lead Finding and LO (Lead optimization). - Assay biomarkers in samples from in house performed animal studies with LO compounds, using ELISA-, RIA-, and cell culturing techniques (in Vitro and ex-Vivo). - Data management, processing and reporting of these outsourced monkey studies using excel and the statistical application SAS. - Development of a generic reporting tool in excel using visual basic for applications, wich reports data from the Animals! application into graphs and tables. This tool proved to be very important for the pharmacology department to visualize data generated at any moment during or after in vivo experiments. - IT/Excel VBA knowledge base within pharmacology department

• Lab Technician Endocrinology

  • 1990 - 2001

  Oss, The Netherlands - Assay biomarkers in samples from in house performed animal studies with LO compounds, using ELISA- , RIA- and cell culturing techniques (Vitro and ex-Vivo) - Assisting in section at the end of in vivo studies e.g. gross anatomy - Data management, processing and reporting of in vivo and in vitro generated data using excel and SAS interfaces - Creation of excel tools for reporting in vitro and in vivo generated data in graphs and tables - Excel VBA knowledge base… Show more - Assay biomarkers in samples from in house performed animal studies with LO compounds, using ELISA- , RIA- and cell culturing techniques (Vitro and ex-Vivo) - Assisting in section at the end of in vivo studies e.g. gross anatomy - Data management, processing and reporting of in vivo and in vitro generated data using excel and SAS interfaces - Creation of excel tools for reporting in vitro and in vivo generated data in graphs and tables - Excel VBA knowledge base within pharmacology department