Experience

Vibliome Therapeutics, LLC

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• VP Chemistry & Informatics

  • Jul 2022 - Present

• VP Cheminformatics

  • Sep 2019 - Present



FRESH Directions Consulting, LLC

• Wayne, PA USA

• Founder & Chief Scientist

  • Oct 2007 - Present

  Consulting to the technology, biotechnology, pharmaceutical and venture capital community - Skilled Integrator with demonstrated experience who works exceptionally well with visionary CEOs - Alliance and Collaboration leadership and management - Drug Discovery Project Management and Direction - CRO Management - Technology Transfer (making viable business opportunities from state-of-the-art approaches to solving problems) - Investor Due Diligence (evaluate biotechnology programs and technologies) - CADD (Computer Aided Drug Discovery) - Informatics and Knowledge Management - Scientific, Technical and Management Consulting Services for the Pharmaceutical, Biotech and Technology Industry - Project Management, collaboration development and alliance management across many different technologies and program areas - providing deliverables on schedule - IT and software development project management and leadership - STEM/ STEAM Instructor with specialization in chemistry, IT, informatics and technology - Lead and co-develop informatics and data analysis software for the pharmaceutical industry which is applicable to many others - Selected Clients: Sphaera Pharma, Ternus Pharma, Cardero Therapeutics, Medivation, Polymedix, Sai Advantium Life Sciences, Boy Scouts of America



Douglas Connect GmbH

• Greater Philadelphia Area

• Vice President of Corporate Operations, Americas

  • Jan 2018 - Jan 2019

  * Bring Douglas Connect's message of "Connecting People & Data for Integrated Safety Solutions" to the Americas. * Establish and develop relationships with select partners and collaborators in the areas of predictive toxicology, integrated testing and data integration as well as safe and predictive alternatives to animal testing. * Contribute as part of Douglas Connect's global strategy team to business planning, marketing, and related scientific, technical and business development. * Bring Douglas Connect's message of "Connecting People & Data for Integrated Safety Solutions" to the Americas. * Establish and develop relationships with select partners and collaborators in the areas of predictive toxicology, integrated testing and data integration as well as safe and predictive alternatives to animal testing. * Contribute as part of Douglas Connect's global strategy team to business planning, marketing, and related scientific, technical and business development.



Sphaera Pharma

• India
• Biotechnology Research
• 1 - 100 Employee

• COO

  • Mar 2014 - Feb 2016

  * Develop TER-819, a pro-drug of propofol, as a general anesthetic using Sphaera’s Drug Modification Technology which has significant aqueous solubility improvement over current formulations* Oversee operations of the Joint Venture* Alliance and program management to ensure projects achieved key objectives

• President

  • Jul 2013 - Feb 2016

  Full operational responsibility to develop a virtual drug discovery and development organization to fully enable the development of drug discovery programs developed by our sister company SP-INDIA

• Vice President, Computation, Informatics & Operations

  • Sep 2008 - Feb 2016

  Sphaera Pharma is an integrated drug discovery and development organization led by pharma and biotech professionals with global experience. Our goal is to bring innovative therapies to patients with unmet medical needs by developing a balanced portfolio of early stage discovery projects and clinical programs.Sphaera combines US based expertise with pre-clinical and clinical resources of Singapore and India, thus creating a novel model for drug discovery and development.

• Vice President

  • Sep 2008 - Feb 2016

  * Duties as defined by the CEO of the company* Provide drug discovery and development leadership to build and evolve Sphaera Pharma into an international Research and Development organization* Alliance management and leadership - Cardero Therapeutics, Ternus Pharma, Inhibikase Therapeutics, D3G, Synthia Dermatech, Colorado Research Partners, ICGEB (Intl Center for Genetic Eng & Biotech., India) & THSTI (Translational Health Science & Technology Institute, India), Mayo Clinic, Johns Hopkins, LeadInvent, Photolitec* Details provided upon request.



Sai Advantium Pharma, Ltd.

• Wayne, PA USA/ Hyderabad, INDIA

• Senior Director, CADD & Informatics

  • Jan 2007 - Oct 2007

  - Lead CADD (computer assisted drug design) and informatics (chemoinformatics a specialty) activities for client companies - Consult in areas of drug discovery from hit/ lead identification stage through IND selection and beyond - Project management of drug discovery collaboration projects between Sai Advantium and our clients (biotech and pharmaceutical companies) - Develop and enable a drug discovery organization within Sai Advantium - Develop and enable contract services for the pharmaceutical industry which took advantage of my skills as a drug hunter, computational chemist and molecular architecture capabilities coupled with my diverse experience in collaboration and alliance management



Locus Pharmaceuticals

• Biotechnology
• 1 - 100 Employee

• Director, Computational Chemistry

  • May 2000 - Dec 2006

  - Development of Locus' core computational technology - Project and Alliance management - corporate and collaboration projects - Project management and leadership of the development of the world's fastest private computer cluster (circa 2004) - Lead a staff of professional computational chemists applying Locus' core computational technology toward internal and collaboration projects - Project managment of collaboration drug discovery projects applying Locus' core technology (collaborations include Speedel, Eli Lilly, Amgen, Scios (J&J), J&J (Raritan), and Dow) - Support business developement to evolve Locus' collaboration efforts



Sarnoff Corporation

• Research Services
• 1 - 100 Employee

• Locus - Group Leader

  • 2000 - 2001



Pfizer

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Research Scientist II

  • Jan 1998 - May 2000

  - Lead computational efforts on numerouse discovery projects - Proactive discovery team member - Drug discovery in interdisciplinary teams (with medicinal chemists, biochemists, biologists, structural groups, business development, project managers) - Computer assisted drug design on ligand-based and structure-based projects - Identify and optimize lead compounds for key therapeutic projects - Employed chemoinformatics as appropriate to identify SARs (structure activity relationships) and trends for drug design and model validation. - Diverse computer hardware experience (SGI/ Irix, Windows, MAC) - Diverse computational chemistry software experience (Accelrys, Schrodinger, Tripos, MDL



Schering-Plough Research Institute

• United States
• Pharmaceutical Manufacturing
• 400 - 500 Employee

• Associate Principal Scientist

  • Oct 1993 - Dec 1997

  - Team leadership positions - Drug discovery in interdisciplinary teams - Computer assisted drug design on ligand-based and structure-based projects - Identify and optimize lead compounds for key therapeutic projects - Diverse computer hardware experience - Diverse computational chemistry software experience (Accelrys, Schrodinger, Tripos, MDL) - Team leadership positions - Drug discovery in interdisciplinary teams - Computer assisted drug design on ligand-based and structure-based projects - Identify and optimize lead compounds for key therapeutic projects - Diverse computer hardware experience - Diverse computational chemistry software experience (Accelrys, Schrodinger, Tripos, MDL)