Floriane BRETHEAU, PhD
Professionnelle de recherche at Cirris- Claim this Profile
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Bio
Experience
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Cirris
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United States
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Appliances, Electrical, and Electronics Manufacturing
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1 - 100 Employee
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Professionnelle de recherche
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Apr 2021 - Present
Professionnelle de recherche en recherche fondamentale clinique Professionnelle de recherche en recherche fondamentale clinique
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PhD Student
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Oct 2015 - Apr 2021
PhD project: Inhibition of interleukine-1 alpha as a neuroprotective therapy for spinal cord injury Main techniques: - Transgenic mouse models (15 different models) - Microscopy (2-photon, confocal,...) - Flow-cytometry - Primary cell culture (monocytes, astrocytes, oligodendrocytes, microglia, endothelial cells) PhD project: Inhibition of interleukine-1 alpha as a neuroprotective therapy for spinal cord injury Main techniques: - Transgenic mouse models (15 different models) - Microscopy (2-photon, confocal,...) - Flow-cytometry - Primary cell culture (monocytes, astrocytes, oligodendrocytes, microglia, endothelial cells)
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ENSTBB Bordeaux INP
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France
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Higher Education
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1 - 100 Employee
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Engineer student
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Sep 2012 - Jun 2015
Multidiscplinary formation in Biotechnology, Master degree Multidiscplinary formation in Biotechnology, Master degree
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Roche
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Switzerland
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Biotechnology Research
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700 & Above Employee
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Intern in Pharma Research and Early Development, Infectious Diseases and Immunology Group
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Jul 2014 - Feb 2015
Industrial work placement, Roche Innovative Center Zurich, Schlieren, Switzerland Main project: Set up of functional immune cellular based assays to study and characterize B cell dysfunction in chronic hepatitis B, focusing on B cell phenotype, activation, proliferation and differentiation, using 10 color flow cytometry. Main techniques: - PBMCs and B cells isolation from human blood - 10-color flow cytometry - proliferation, activation and differentiation assays - ELISA Industrial work placement, Roche Innovative Center Zurich, Schlieren, Switzerland Main project: Set up of functional immune cellular based assays to study and characterize B cell dysfunction in chronic hepatitis B, focusing on B cell phenotype, activation, proliferation and differentiation, using 10 color flow cytometry. Main techniques: - PBMCs and B cells isolation from human blood - 10-color flow cytometry - proliferation, activation and differentiation assays - ELISA
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Fluofarma
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France
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Pharmaceutical Manufacturing
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Work Placement
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Jun 2013 - Aug 2013
Industrial work placement Fluofarma , specialized in high throughput content screening, Pessac, France Projects: Set up of a Tissue Micro Array composed by 60 different Human Tumorous Cell lines and protein expression study in murine glioblastoma by immunohistochemistry. Main techniques: - Cell culture - Immunohistochemistry Industrial work placement Fluofarma , specialized in high throughput content screening, Pessac, France Projects: Set up of a Tissue Micro Array composed by 60 different Human Tumorous Cell lines and protein expression study in murine glioblastoma by immunohistochemistry. Main techniques: - Cell culture - Immunohistochemistry
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Work Placement
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Jun 2011 - Jul 2011
- Study of obesogenic molecules impact on Danio rerio model - Study of obesogenic molecules impact on Danio rerio model
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Education
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Université Laval
PhD Student, Molecular medicine -
ENSTBB
Diplôme d'ingénieur, Biotechnologies