Fengling Liu

Director of Protein Science at Juvena Therapeutics
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Redwood City, California, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Director of Protein Science
      • 2022 - Present

      Redwood City, California, United States

    • United States
    • Biotechnology
    • 300 - 400 Employee
    • Principal Investigator, group lead of Protein Science
      • 2020 - 2022

      Hayward, California, United States

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Sr. Scientist, Protein Biochemistry-Antibody target identification and conformation
      • 2019 - 2020

      South San Francisco, California, United States

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Staff Scientist, Protein Biochemistry and assay development
      • 2016 - 2018

      Redwood City, California, United States

    • United Kingdom
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Scientist II, Protein Biochemistry-Lead optimization
      • 2010 - 2013

      Mountain View, California, United States • Served as the biochemistry lead in multiple cross-functional teams for subunit vaccine development against infectious diseases •Established a CHO transient expression platform for difficult-to-express viral glycoproteins production (titer improved 50-100 fold) for immunizations • Successfully optimized protein targets by reducing aggregation and heterogeneity using structure-based protein engineering • Excellent in protein purification method development and… Show more • Served as the biochemistry lead in multiple cross-functional teams for subunit vaccine development against infectious diseases •Established a CHO transient expression platform for difficult-to-express viral glycoproteins production (titer improved 50-100 fold) for immunizations • Successfully optimized protein targets by reducing aggregation and heterogeneity using structure-based protein engineering • Excellent in protein purification method development and characterization tools (e.g., HPLC, DLS and ELISA) • Supervised multiple associates and managed CROs Show less

    • Hospitals and Health Care
    • 1 - 100 Employee
    • Postdoctoral Researcher, Protein biochemistry and Crystal Structural studies
      • 2007 - 2010

      • Studied human herpesvirus Epstein-Barr Virus (EBV) and cytomegalovirus (CMV) glycoprotein interactions to dissect viral entry mechanisms • Designed multiple glycoprotein and Fab constructs for gene synthesis • Expressed multiple glycoproteins (up to 5 proteins co-transfection) in baculovirus/insect cells and HEK293 to study protein-protein interactions • Developed and optimized a fluorescence polarization binding (protein-protein or peptide) assay for high throughput… Show more • Studied human herpesvirus Epstein-Barr Virus (EBV) and cytomegalovirus (CMV) glycoprotein interactions to dissect viral entry mechanisms • Designed multiple glycoprotein and Fab constructs for gene synthesis • Expressed multiple glycoproteins (up to 5 proteins co-transfection) in baculovirus/insect cells and HEK293 to study protein-protein interactions • Developed and optimized a fluorescence polarization binding (protein-protein or peptide) assay for high throughput screening of small molecule libraries for EBV entry inhibitors • Crystallized protein complexes with small molecules Show less

Education

  • Georgia State University
    PhD, Molecular Biology, protein engineering and Crystallography
  • Zhongshan University
    Master of Science (MS), Life sciences

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