Federico Casale

Machine Learning and Breeding Informatics Analyst at Computomics
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Contact Information
us****@****om
(386) 825-5501
Location
Tübingen, Baden-Württemberg, Germany, DE
Languages
  • Español Native or bilingual proficiency
  • Inglés Full professional proficiency
  • Italiano Professional working proficiency

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Experience

    • Germany
    • Biotechnology Research
    • 1 - 100 Employee
    • Machine Learning and Breeding Informatics Analyst
      • Jan 2023 - Present

    • Germany
    • Higher Education
    • 700 & Above Employee
    • Researcher PhD Candidate at Quantitative Genetics and Genomics of Plants
      • Sep 2018 - Dec 2022

      The QGGP institute (mpipz.mpg.de/stich) utilizes state-of-the-art bioinformatics with genomic and non-genomic data to create novel tools for plant breeding. Here, I apply different computational approaches to unravel the inheritance of agronomical traits to develop genomic selection models. In particular, I am focused on generating barley populations with altered recombination. -Data analysis in R and Python. Linux shell scripting and data management in HPC. -Hypothesis testing, Regressions, and Mixed models. ML: Random Forest and ANNs. -Genomic analysis of NGS big data sets - DNA (SNPs, SVs, and methylome) as well as RNA-seq. Multi-omics data integration and modeling. -Genetic/breeding tools: genomic prediction, GWAS, genetic map construction, and QTL mapping. -Teaching genetic map construction in R. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Research Assistant at Molecular Weed Science Lab
      • Aug 2015 - May 2018

      The lab is a leader in unraveling the genetic basis and evolution of the occurrence of herbicide resistance in invasive plant populations. Most of my research was on calculating the de novo mutation rate conferring herbicide resistance in plants. -Data analysis in SAS and R. -Lab (DNA extractions, PCR, qPCR, Sanger sequencing) and greenhouse work. -Teaching weed science. The lab is a leader in unraveling the genetic basis and evolution of the occurrence of herbicide resistance in invasive plant populations. Most of my research was on calculating the de novo mutation rate conferring herbicide resistance in plants. -Data analysis in SAS and R. -Lab (DNA extractions, PCR, qPCR, Sanger sequencing) and greenhouse work. -Teaching weed science.

    • Argentina
    • Farming
    • 1 - 100 Employee
    • Grain Production Responsible
      • 2013 - 2014

      Corn, soybean, and wheat production on more than 6,000 acres of arable land. Planting and fertilization control and supply. Soil erosion prevention. Integrated pest management. Harvest management. Corn, soybean, and wheat production on more than 6,000 acres of arable land. Planting and fertilization control and supply. Soil erosion prevention. Integrated pest management. Harvest management.

    • International Trade and Development
    • 700 & Above Employee
    • Cattle Commercial Associate
      • 2012 - 2013

      Cattle purchase and trade. Retail sales analysis. Price policies. Cattle purchase and trade. Retail sales analysis. Price policies.

    • United States
    • Government Administration
    • 700 & Above Employee
    • Certification Auxiliary
      • Sep 2011 - Jan 2012

      Certificate issuance. Blueberries and Cherries inspection. Certificate issuance. Blueberries and Cherries inspection.

    • Argentina
    • Education
    • 200 - 300 Employee
    • Undergrad TA & RA
      • 2010 - 2012

      Research in fruit flies reproductive development. Teaching basic genetics and plant breeding. Research in fruit flies reproductive development. Teaching basic genetics and plant breeding.

Education

  • University of Düsseldorf
    Doctor of Philosophy - PhD, Quantitative Genetics and Genomics
    2018 - 2022
  • University of Illinois at Urbana-Champaign
    Master of Science (M.S.), Plant Genetics
    2015 - 2018
  • Universidad de Buenos Aires
    Engineer's degree, Agronomy and Crop Science
    2006 - 2012

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