Experience

Petersburg Nuclear Physics Institute, National Research Centre "Kurchatov Institute"

• Research Services
• 1 - 100 Employee

• lab leader

  • Aug 1984 - Present

  Multistep organic synthesis, synthesis of carbohydrate derivatives, including thioglycosides, thiooligosaccharides, carbohydrate mimetics, peptides, glycosylaminoacids and glycopeptides. Design of new anticancer agents based upon inhibitors of histone deacetylases, DNA recombinase Rad51 (heterocyclic compounds), and enzymes involved in glycolysis. Design of anti-fungal drugs. Design of affinity chromatography media for purification of enzymes and proteins. Protein and peptide modification (labeling) and immobilization on a solid phase, synthesis of fluogenic and chromogenic substrates for carbohydrate processing enzymes discover and studies. Show less



Petersburg Nuclear Physics Institute National Research Center Kurchatov Institute

• Gatchina, Leningrad, Russia

• Head Of Laboratory

  • Aug 1984 - Present

  Synthesis of carbohydrate derivatives, including thioglycosides, thiooligosaccharides, carbohydrate mimetics, peptides, glycosylaminoacids and glycopeptides. Design of new anticancer agents based upon inhibitors of histone deacetylases, DNA recombinase Rad51 (heterocyclic compounds), and enzymes involved in glycolysis. Design of anti-fungal drugs. Design of affinity chromatography media for purification of enzymes and proteins. Protein and peptide modification (labeling), synthesis of fluogenic and chromogenic substrates for carbohydrate processing enzymes discover and studies. Show less



Baltpharma LLC

• St Petersburg, St Petersburg City, Russia

• Chemistry Scientist

  • Feb 2018 - Jun 2019

  Development of synthesis of tadalafil and some other active pharmaceutical substances using flow chemistry (Ehrfeld Mikrotechnik, Germany) equipment. Development of synthesis of tadalafil and some other active pharmaceutical substances using flow chemistry (Ehrfeld Mikrotechnik, Germany) equipment.



Saint-Petersburg Technopark, Engeneering Center of Active Pharmaceutical substances

• St Petersburg, St Petersburg City, Russia

• Scientific Leader

  • Aug 2016 - Jun 2019

  R&D in the field of synthesis of active pharmaceutical substances using flow chemistry approach. R&D in the field of synthesis of active pharmaceutical substances using flow chemistry approach.



KTH Royal Institute of Technology

• Sweden
• Higher Education
• 700 & Above Employee

• Visiting Scientist

  • Mar 2006 - Jul 2009

  Synthesis of fluogenic and chromogenic substrates for biochemical and histochemical investigation of carbohydrate processing enzymes. Synthesis of substrates for xyloglucan-synthases. Biochemical investigation of glycosyl hydrolases. Synthesis of fluogenic and chromogenic substrates for biochemical and histochemical investigation of carbohydrate processing enzymes. Synthesis of substrates for xyloglucan-synthases. Biochemical investigation of glycosyl hydrolases.



CERMAV-CNRS

• Grenoble, France

• Visiting Scientist

  • Nov 1998 - May 1999

  Synthesis of 4-thiomaltooligosaccarides (up to dp10) as potential inhibitors for Barley - amylase 1 and 2. Synthesis of 4-thiomaltooligosaccarides (up to dp10) as potential inhibitors for Barley - amylase 1 and 2.



Institut fur Organische Chemie, RWTH Aachen University

• Aachen, North Rhine-Westphalia, Germany

• Visiting Scientist

  • Jul 1996 - May 1997

  Synthesis of some thio-linked analogues of 5’a-carbamaltose and 5’’a-carbamaltotriose as potential inhibitors for glucoamylases Synthesis of some thio-linked analogues of 5’a-carbamaltose and 5’’a-carbamaltotriose as potential inhibitors for glucoamylases