Evie Maifoshie PhD MBA

Director of Clinical Partnerships at Aria Health
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Contact Information
us****@****om
(386) 825-5501
Location
CY
Languages
  • Greek Native or bilingual proficiency
  • English Full professional proficiency

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Michael Schneider

Evie was a terrific post-graduate student in every imaginable way. Energetic, curious, painstaking, fearless. Her dissertation research centered on the establishment of high-throughput, high-content automated microscopy assays of human cardiac muscle cell death, using iPSC derivatives as a platform for improved translation. More specifically, Evie worked on applying these methods to pinpoint MAP4K4/HGK as a pivotal mediator of human cardiac cell death due to oxidative stress. She performed the target validation assays using RNAi, and set the stage for a large-scale Wellcome Trust-supported drug discovery endeavour. We now have many compounds that rescue human cardiac myocytes, have take the best ones forward successfully into mice (50-60% suppression of infarct size), and will start large-mammal studies of the best two this fall. It all started with Evie!!

Shankaran Sundarajoo

Collaborating with Evie was a great experience. Evie is someone who is frank and honest when providing her views which makes discussions so much more authentic. I admire her level of passion when expressing her views and she did a remarkeable job of preparing data that was to be presented! I look forward to working with her again.

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Credentials

  • Health Economics: Application to Research
    WA Health Translation Network - RETP
    Jul, 2018
    - Nov, 2024

Experience

    • Cyprus
    • Hospitals and Health Care
    • 1 - 100 Employee
    • Director of Clinical Partnerships
      • Feb 2023 - Present

    • Switzerland
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Health Solutions Specialist, Oncology
      • Jan 2022 - Dec 2022

    • Cyprus
    • Research Services
    • 1 - 100 Employee
    • Research and Development Project Manager
      • Nov 2020 - Jan 2022

      We are a team of professionals with over 50 years of collective experiences in the fields of Education, System Rationalization, Information & Communications Technologies, Entrepreneurship, Social Innovation, Global Health Process – Life Sciences and Business Forensic Intervention focusing on developing and introducing disruptive solutions to systemic social, education and economic problems. Our projects are executed in collaboration with a host of partners across the European Union. Check out our work here: http://csicy.com/our-work/pojects2/

    • United States
    • Higher Education
    • 100 - 200 Employee
    • Executive MBA
      • Apr 2019 - Aug 2020

    • Exploring Australia & South East Asia
      • Jan 2018 - Dec 2018

      Traveling is like knowledge, the more you see, the more you know you haven't seen. It is very much like science, the more you dive deeper, the more you know you don't know and the more curious you become. I embraced my curiosity, love for learning, and faced my fears. I listened to people from all walks of life, and saw how many more similarities, than differences, we have with each other. People are not failures, systems are. Traveling opened up my heart, broadened my mind, and filled my life with stories to share. Solo traveling wasn't easy or pretty. Traveling broke my heart, inspired me, changed me, made me more vulnerable and patient. Travel, listen, converse, feel, fail, feel, try again, grow, repeat. No shortcuts.

    • United Kingdom
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Imaging Specialist/Manager
      • Nov 2016 - Jan 2018

      As a Consultant and Business Area Manager in Imaging, I focused on data management, training colleagues in image acquisition and analysis and facilitated networking opportunities for collaboration and business development. Consulted drug programs as an Imaging Analysis expert. Trained in TIBCO Spotfire and other software packages as a member of the local data support team and became adept in handling and interpreting data. Published strategic initiatives and delivered results in the area of alternative cell models and imaging as part of R&D modernization.

    • Senior Data Scientist
      • May 2014 - Nov 2016

      As a scientist within Screening Profiling & Mechanistic Biology (SPMB) department I focused on the discovery of compounds in respiratory and inflammatory diseases and embedding new technologies within the drug discovery framework. Accustomed to generate, analyse data and effectively communicate results to multidisciplinary program teams to drive evidence-based research. Technical skills:• Cell-based culture techniques (primary cell isolation, stem cells and differentiation into various products)• Complex assay development and optimization for target validation and high-throughput screening (HTS) using specific technologies.• Developed deep expertise in specific technologies (imaging, flow cytometry, Imaging/Flow cytometry, qPCR, automation handling).• Experience in the drug discovery process from hit identification to candidate selection. • Extensive knowledge in cell death assays and data extraction from microscopy-based imaging using imaging analytics software (Definiens, Columbus, INCell)Mentoring/Coaching:• Developed young scientists who undertake industrial placement year in the department by running a scientific Journal Club for 2 years to encourage critical thinking and communication skills.• Coached a student by investing time in their career development and delivered results as part of an R&D project.

    • Research Services
    • 700 & Above Employee
    • PhD Cardiovascular Research
      • Oct 2009 - Nov 2013

      The basis of heart failure is the extensive loss of heart muscle cells. To rescue heart muscle cell numbers one strategy is the pharmacological inhibition of cell death. I identified conditions of cell death in a stem-cell derived model and proved that by inhibiting a protein (MAP4K4) using genetic technology (miRNAs) and drugs is a successful strategy for future therapy. I executed biological assays and developed image analytic tools that were later used to validate drug hits from a medium-throughput screen. I regularly presented results in meetings and became adept at problem-solving and producing results. Results were used for a scientific publication and complemented a compound patent application.

    • MRes Biomedical Research
      • Sep 2008 - Sep 2009

      Masters in Research investigating the role of proteins in breast cancer and building tools for cardiovascular science. Awarded with Distinction.

    • United Kingdom
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Project in Intestinal Cancer
      • Jan 2008 - May 2008

      Lab-based research and project management on colon cancer (in Prof. Alan Clarke lab). Produced results and drove research forward. Lab-based research and project management on colon cancer (in Prof. Alan Clarke lab). Produced results and drove research forward.

    • United Kingdom
    • Research
    • 1 - 100 Employee
    • Research Scientist
      • Sep 2006 - Aug 2007

      Research focus on the genetic basis of alpha-thalassaemia/mental retardation (ATR-16) syndrome. Produced results using various methodologies that disproved a hypothesis. Research focus on the genetic basis of alpha-thalassaemia/mental retardation (ATR-16) syndrome. Produced results using various methodologies that disproved a hypothesis.

Education

  • Quantic School of Business and Technology
    Executive MBA program
    2019 - 2020
  • Imperial College London
    Doctor of Philosophy - PhD, Clinical Cardiovascular Research
    2009 - 2014
  • Imperial College London
    MRes, Biomedical Research
    2008 - 2009
  • Cardiff University / Prifysgol Caerdydd
    BSc, Medical Molecular Biology
    2004 - 2008

Community

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