Senior Scientist

• Nov 2022 - Present

Principal Scientist

• Jul 2017 - Oct 2022

Senior Scientist

• Jan 2016 - Jul 2017

Senior Postdoctoral Scientist

• 2013 - 2015

This was a collaborative project involving the Edinburgh Cancer Research Centre and INSERM, Molecular Genetics Institute, St Louis Hospital, Paris. The project focused on Comparative Oncology and brought together biologist, clinicians and veterinarians from a number of institutes throughout Europe. The main aim of the project was to work towards the development of canine specific monoclonal antibodies for use as both diagnostics and therapeutics in veterinary medicine. To develop these antibodies we constructed a canine single chain (scFV) antibody phage display library which we used in addition to the more tradition mouse hybridoma technology. Show less

Senior Researcher

• Dec 2011 - Jan 2013

This position allowed me to split my time between Brno and Edinburgh and help to coordinate a number of collaborative projects between this lab and my previous lab. The projects included the investigation of a number of pathways involved in cancer cell signalling with one of the main goals being to identify targetable hubs for future therapeutic intervention. In addition we also had a number of clinical proteomic projects where we used both label and label free mass spectrometry based proteomic methods to profile the proteomes of a number of different cancer types. Show less

Postdoctoral Research Assistant

• Aug 2004 - Nov 2011

This project was part of the BBSRC/EPSERC funded RASOR (Radical Solutions for Researching the Proteome) consortium, an inter-disciplinary group of scientists based at four Scottish Universities. I was primarily based at the Edinburgh Cancer Research Centre where working under the supervision of Professor Ted Hupp the main aim of my project was to develop peptide aptamers which can specifically recognise proteins of interest which the consortium could utilise in its proteomic studies. I spent the majority of my time in a molecular cell biology lab where peptide- or antibody-phage display was used to develop these aptamers which were subsequently used by ourselves and other members of the consortium to target specific proteins of interest. In addition to this the project required me to be proficient in all of the techniques that one would expect in a molecular cell biology lab such as, cloning, protein purification, general tissue culture, ELISA, Western blotting, qRT-PCR, immunoprecipitations, etc. Show less