Eric Nalefski
Senior Research Scientist at GH Labs- Claim this Profile
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Experience
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GH Labs
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United States
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Research Services
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1 - 100 Employee
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Senior Research Scientist
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Jul 2020 - Present
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Intellectual Ventures
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United States
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Venture Capital and Private Equity Principals
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100 - 200 Employee
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Senior Scientist
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Jan 2020 - Jul 2020
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Research Scientist
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Apr 2018 - Jan 2020
As a bench scientist, I am developing molecular assays for use in resource poor settings.
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Contractor
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Oct 2017 - Apr 2018
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University of New Haven
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United States
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Higher Education
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700 & Above Employee
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Adjunct Lecturer
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Jan 2012 - Jul 2015
Teaching focus: Molecular Biology of Proteins and Nucleic Acids. Courses taught: Molecular Biology of Nucleic Acids, with Lab (MB 613), Protein Biochemistry and Enzymology (MB 601), Evaluation of Scientific Literature (BIOL 493), Molecular Biology of Proteins, with Lab (CMBI 6601), and Protein Biochemistry and Enzymology (CMBI 6613). Teaching focus: Molecular Biology of Proteins and Nucleic Acids. Courses taught: Molecular Biology of Nucleic Acids, with Lab (MB 613), Protein Biochemistry and Enzymology (MB 601), Evaluation of Scientific Literature (BIOL 493), Molecular Biology of Proteins, with Lab (CMBI 6601), and Protein Biochemistry and Enzymology (CMBI 6613).
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Wesleyan University
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Higher Education
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700 & Above Employee
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Visiting Assistant Professor
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Aug 2014 - Jun 2015
Teaching focus: Molecular Biology and Biochemistry. Courses taught: Molecular Biology (MB&B 208), Biochemistry (CHEM 383), and Medical Biochemistry (MB&B 228). Teaching focus: Molecular Biology and Biochemistry. Courses taught: Molecular Biology (MB&B 208), Biochemistry (CHEM 383), and Medical Biochemistry (MB&B 228).
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Merrimack College
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United States
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Higher Education
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700 & Above Employee
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Adjunct Instructor
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Aug 2011 - Dec 2011
Course taught: Genetics (BIO4006C). Course taught: Genetics (BIO4006C).
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Consultant/Contract Scientist
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Oct 2010 - Mar 2011
Validated performance of fluorescence correlation spectroscopy instrument and advised collaborators at the National Cancer Institute (Frederick, MD) on experimental design and data analysis. Activities included bench experimentation, data analysis, presenting data to collaborators. Validated performance of fluorescence correlation spectroscopy instrument and advised collaborators at the National Cancer Institute (Frederick, MD) on experimental design and data analysis. Activities included bench experimentation, data analysis, presenting data to collaborators.
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US Genomics
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United States
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Biotechnology
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1 - 100 Employee
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Scientist
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2001 - 2009
As bench scientist, developed reagents and in vitro assays for single-molecule fluorescence detection, including spatial mapping of DNA using fluorescent transcription factors, determination of equilibrium/kinetic constants for transcription factor-DNA interactions, single-nucleotide polymorphism detection/haplotyping, and solution-phase immunoassays. Activities included engineering, expression, fluorescent labeling and purification of DNA-binding proteins, chemical and enzymatic labeling of DNA and antibodies with fluorophores, operating single-molecule instrument and data analysis software, training and managing small groups of research associates. Development and validation of ultra-sensitive quantitative assays based on single-molecule fluorescence detection, including particle-based immunoassays for detecting cytokines, chemokines and cardiac protein markers in clinical serum/plasma and oligonucleotide-based assays for detecting genetically-modified organisms in seed crops. Activities included developing research plans, establishing and monitoring progress against milestones, drafting reports for and presenting data to external collaborators, serving as primary author on published manuscripts, writing SOPs, training and mentoring scientists, and participating in bench experimentation. Show less
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University of California at San Diego
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United States
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Hospitals and Health Care
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1 - 100 Employee
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Post-doctoral fellow
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1999 - 2001
Pharmacology Department Advisor: Dr. Alexandra Newton Research Focus: Activation mechanisms of protein kinase C in signal transduction pathways elucidated by biophysical approaches. Pharmacology Department Advisor: Dr. Alexandra Newton Research Focus: Activation mechanisms of protein kinase C in signal transduction pathways elucidated by biophysical approaches.
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University of Colorado at Boulder
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United States
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Technology, Information and Internet
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Post-doctoral fellow
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1995 - 1999
Department of Chemistry and Biochemistry Advisor: Dr. Joseph Falke Research Focus: Ca2+-activated, membrane-binding proteins in mammalian signal transduction characterized by biophysical approaches; development of in vitro assays for measuring protein binding to synthetic phospholipids membranes. Department of Chemistry and Biochemistry Advisor: Dr. Joseph Falke Research Focus: Ca2+-activated, membrane-binding proteins in mammalian signal transduction characterized by biophysical approaches; development of in vitro assays for measuring protein binding to synthetic phospholipids membranes.
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Post-doctoral fellow
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May 1993 - Aug 1995
Small Molecule Drug Discover Advisor: Dr. James D. Clark Research Focus: Activation mechanisms and structure of cytosolic phospholipase A2 in inflammatory and signal transduction pathways elucidated by biochemical and biophysical approaches. Small Molecule Drug Discover Advisor: Dr. James D. Clark Research Focus: Activation mechanisms and structure of cytosolic phospholipase A2 in inflammatory and signal transduction pathways elucidated by biochemical and biophysical approaches.
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Education
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Harvard University
PhD, Cell and Developmental Biology -
University of Chicago
A.B., Biology