Experience

Mural Oncology

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Nov 2023 - Present



Alkermes

• Ireland
• Biotechnology Research
• 700 & Above Employee

• Senior Scientist

  • Apr 2023 - Present

  Provide subject matter expertise in chromatography analytical development activities at Alkermes requiring internal laboratory execution and oversight/technical supervision of contractors. Guide and drive analytical method development, implementation as well as drug substance and drug product characterization and control for pre-clinical and early clinical stage development programs Design validation protocols that are in compliance with ICH and FDA guidelines, identify critical… Show more Provide subject matter expertise in chromatography analytical development activities at Alkermes requiring internal laboratory execution and oversight/technical supervision of contractors. Guide and drive analytical method development, implementation as well as drug substance and drug product characterization and control for pre-clinical and early clinical stage development programs Design validation protocols that are in compliance with ICH and FDA guidelines, identify critical factors that may not be mandated by the guidelines but are essential for validating the methods for their intended use Show less Provide subject matter expertise in chromatography analytical development activities at Alkermes requiring internal laboratory execution and oversight/technical supervision of contractors. Guide and drive analytical method development, implementation as well as drug substance and drug product characterization and control for pre-clinical and early clinical stage development programs Design validation protocols that are in compliance with ICH and FDA guidelines, identify critical… Show more Provide subject matter expertise in chromatography analytical development activities at Alkermes requiring internal laboratory execution and oversight/technical supervision of contractors. Guide and drive analytical method development, implementation as well as drug substance and drug product characterization and control for pre-clinical and early clinical stage development programs Design validation protocols that are in compliance with ICH and FDA guidelines, identify critical factors that may not be mandated by the guidelines but are essential for validating the methods for their intended use Show less



Vertex Pharmaceuticals

• United States
• Biotechnology Research
• 700 & Above Employee

• Scientist

  • Aug 2022 - Apr 2023

  Co-employment with Thermo Fisher Scientific PPD focusing on analytical development: Complete analytical test methods to support the clinical development of new pipeline candidates and release testing of commercial products. Verify and pre-validate analytical test methods in preparation for method transfer to GMP CMO facilities. Investigate and evaluate groundbreaking biophysical and analytical instrumentation and stay up to date on innovative methodologies for AAV characterization.(LC-MS,… Show more Co-employment with Thermo Fisher Scientific PPD focusing on analytical development: Complete analytical test methods to support the clinical development of new pipeline candidates and release testing of commercial products. Verify and pre-validate analytical test methods in preparation for method transfer to GMP CMO facilities. Investigate and evaluate groundbreaking biophysical and analytical instrumentation and stay up to date on innovative methodologies for AAV characterization.(LC-MS, ELSD-HPLC, SEC, SEC-MALS, etc.) Authoring/reviewing documentation to support new and existing commercial products (methods, SOPs, transfer protocols/reports, lab notebooks, technical reports, etc.) Show less Co-employment with Thermo Fisher Scientific PPD focusing on analytical development: Complete analytical test methods to support the clinical development of new pipeline candidates and release testing of commercial products. Verify and pre-validate analytical test methods in preparation for method transfer to GMP CMO facilities. Investigate and evaluate groundbreaking biophysical and analytical instrumentation and stay up to date on innovative methodologies for AAV characterization.(LC-MS,… Show more Co-employment with Thermo Fisher Scientific PPD focusing on analytical development: Complete analytical test methods to support the clinical development of new pipeline candidates and release testing of commercial products. Verify and pre-validate analytical test methods in preparation for method transfer to GMP CMO facilities. Investigate and evaluate groundbreaking biophysical and analytical instrumentation and stay up to date on innovative methodologies for AAV characterization.(LC-MS, ELSD-HPLC, SEC, SEC-MALS, etc.) Authoring/reviewing documentation to support new and existing commercial products (methods, SOPs, transfer protocols/reports, lab notebooks, technical reports, etc.) Show less



Eurofins

• Luxembourg
• Biotechnology Research
• 700 & Above Employee

• Senior Scientist

  • 2021 - Aug 2022

  Method development and sample analysis for identification/quantitation of drug/nutrition metabolites in in vitro and in vivo samples in GL/MP environment for validation assays. Execution and validation of proteomics projects of protein characterizations and targeted protein quantitation. Successfully completed 10+ regulated method development and validation projects. Method development and sample analysis for identification/quantitation of drug/nutrition metabolites in in vitro and in vivo samples in GL/MP environment for validation assays. Execution and validation of proteomics projects of protein characterizations and targeted protein quantitation. Successfully completed 10+ regulated method development and validation projects.



AnTolRx, Inc.

• Scientist

  • Apr 2020 - Jul 2020

  Designing and modifying the protocols to evaluate and quality control for the analytes in the process of immune responses to various antigen and adjuvant combinations. Designing and modifying the protocols to evaluate and quality control for the analytes in the process of immune responses to various antigen and adjuvant combinations.



University of Kentucky

• United States
• Higher Education
• 700 & Above Employee

• Associate Research Scientist

  • 2019 - 2020

  Protein analytical and preparation: Expressed and purified over 20 proteins from capuramycin and albomycin biosynthetic gene clusters using bacterial expression systems Development and optimization of quantitative CE-SDS, HPLC, PCR, LC/MS, ESI/MALDI mass spectometry for protein characterization or proteomics applications in enzyme function during the biosynthesis of nucleoside antibiotics Small molecule analysis:Developed liquid chromatographic methods (UV-Vis, fluorescence, CD… Show more Protein analytical and preparation: Expressed and purified over 20 proteins from capuramycin and albomycin biosynthetic gene clusters using bacterial expression systems Development and optimization of quantitative CE-SDS, HPLC, PCR, LC/MS, ESI/MALDI mass spectometry for protein characterization or proteomics applications in enzyme function during the biosynthesis of nucleoside antibiotics Small molecule analysis:Developed liquid chromatographic methods (UV-Vis, fluorescence, CD, SEC-MALS, CE, DLS, DSC) to separate and characterize 10+ nucleoside analogues from microbial metabolites and enzymatic reaction mixtures Show less Protein analytical and preparation: Expressed and purified over 20 proteins from capuramycin and albomycin biosynthetic gene clusters using bacterial expression systems Development and optimization of quantitative CE-SDS, HPLC, PCR, LC/MS, ESI/MALDI mass spectometry for protein characterization or proteomics applications in enzyme function during the biosynthesis of nucleoside antibiotics Small molecule analysis:Developed liquid chromatographic methods (UV-Vis, fluorescence, CD… Show more Protein analytical and preparation: Expressed and purified over 20 proteins from capuramycin and albomycin biosynthetic gene clusters using bacterial expression systems Development and optimization of quantitative CE-SDS, HPLC, PCR, LC/MS, ESI/MALDI mass spectometry for protein characterization or proteomics applications in enzyme function during the biosynthesis of nucleoside antibiotics Small molecule analysis:Developed liquid chromatographic methods (UV-Vis, fluorescence, CD, SEC-MALS, CE, DLS, DSC) to separate and characterize 10+ nucleoside analogues from microbial metabolites and enzymatic reaction mixtures Show less