Elsa Hay

Senior Associate Scientist at OncoResponse
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Seattle, Washington, United States, US

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
You need to have a working account to view this content.

Experience

    • United States
    • Research
    • 1 - 100 Employee
    • Senior Associate Scientist
      • Feb 2023 - Oct 2023

      Design, execute, and interpret experiments with primary immune cells to discover and develop antibodies modulating the tumor microenvironment for the development of cancer therapeutics. -Plan, execute, and analyze 62 cell-based functional assays and immunophenotyping contributing results to an IND submission, a board meeting, and four project meetings. -Develop and implement complex immunological assays for mechanistic insight and target validation. -Order and coordinate the… Show more Design, execute, and interpret experiments with primary immune cells to discover and develop antibodies modulating the tumor microenvironment for the development of cancer therapeutics. -Plan, execute, and analyze 62 cell-based functional assays and immunophenotyping contributing results to an IND submission, a board meeting, and four project meetings. -Develop and implement complex immunological assays for mechanistic insight and target validation. -Order and coordinate the processing of Leukopaks for the nine-member Immuno-Oncology Department using strong organizational skills. - Determine EC50s of candidate antibodies binding to cells expressing target using 384-well flow cytometry. -Measure six donor’s antigen-specific T-cell response to HPV and CMV and followed-up by evaluating antibody modulation of the response utilizing science-driven decision making. Show less Design, execute, and interpret experiments with primary immune cells to discover and develop antibodies modulating the tumor microenvironment for the development of cancer therapeutics. -Plan, execute, and analyze 62 cell-based functional assays and immunophenotyping contributing results to an IND submission, a board meeting, and four project meetings. -Develop and implement complex immunological assays for mechanistic insight and target validation. -Order and coordinate the… Show more Design, execute, and interpret experiments with primary immune cells to discover and develop antibodies modulating the tumor microenvironment for the development of cancer therapeutics. -Plan, execute, and analyze 62 cell-based functional assays and immunophenotyping contributing results to an IND submission, a board meeting, and four project meetings. -Develop and implement complex immunological assays for mechanistic insight and target validation. -Order and coordinate the processing of Leukopaks for the nine-member Immuno-Oncology Department using strong organizational skills. - Determine EC50s of candidate antibodies binding to cells expressing target using 384-well flow cytometry. -Measure six donor’s antigen-specific T-cell response to HPV and CMV and followed-up by evaluating antibody modulation of the response utilizing science-driven decision making. Show less

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist
      • Aug 2020 - Jul 2022

      In vitro cell assay development and execution to evaluate mechanism of action (MOA) and potency of antibody-drug conjugates (ADC) designed for the treatment of cancer, autoimmune, and liver disease. - Generation of quality results for use in conference poster presentations and IND reports. - Functional area expert on project teams, which included collaboration across departments. - Regularly generated and presented updates at project team, departmental, and all company meetings -… Show more In vitro cell assay development and execution to evaluate mechanism of action (MOA) and potency of antibody-drug conjugates (ADC) designed for the treatment of cancer, autoimmune, and liver disease. - Generation of quality results for use in conference poster presentations and IND reports. - Functional area expert on project teams, which included collaboration across departments. - Regularly generated and presented updates at project team, departmental, and all company meetings - Experienced with electronic lab notebook platforms including Benchling. - Participated in the interviewing, onboarding, and training of new team members Show less In vitro cell assay development and execution to evaluate mechanism of action (MOA) and potency of antibody-drug conjugates (ADC) designed for the treatment of cancer, autoimmune, and liver disease. - Generation of quality results for use in conference poster presentations and IND reports. - Functional area expert on project teams, which included collaboration across departments. - Regularly generated and presented updates at project team, departmental, and all company meetings -… Show more In vitro cell assay development and execution to evaluate mechanism of action (MOA) and potency of antibody-drug conjugates (ADC) designed for the treatment of cancer, autoimmune, and liver disease. - Generation of quality results for use in conference poster presentations and IND reports. - Functional area expert on project teams, which included collaboration across departments. - Regularly generated and presented updates at project team, departmental, and all company meetings - Experienced with electronic lab notebook platforms including Benchling. - Participated in the interviewing, onboarding, and training of new team members Show less

    • United States
    • Higher Education
    • 1 - 100 Employee
    • Temporary Laboratory Technician for COVID-19 Clinical Trials
      • Apr 2020 - Aug 2020

      Process patient samples in Biological Safety Cabinet (BSC) while maintaining sample integrity and safety. Provide suggestions for process improvement. Assist in the testing of a novel device for FDA submission. Process patient samples in Biological Safety Cabinet (BSC) while maintaining sample integrity and safety. Provide suggestions for process improvement. Assist in the testing of a novel device for FDA submission.

    • Pharmaceutical Manufacturing
    • 1 - 100 Employee
    • Associate Scientist in Cellular Immunology
      • Dec 2009 - Nov 2014

      Design, execute, and analyze in vitro studies to validate the biology of candidate drug targets in the therapeutic area of autoimmunity and inflammation in the Cellular Immunology Department. - Performed studies using antibodies or other protein-fusions targeting a range of membrane and soluble targets on various immune cell types with primary focus on protein therapeutics, including: T-cell, macrophage, dendritic, and monocyte cell assays looking for the modulation of activation… Show more Design, execute, and analyze in vitro studies to validate the biology of candidate drug targets in the therapeutic area of autoimmunity and inflammation in the Cellular Immunology Department. - Performed studies using antibodies or other protein-fusions targeting a range of membrane and soluble targets on various immune cell types with primary focus on protein therapeutics, including: T-cell, macrophage, dendritic, and monocyte cell assays looking for the modulation of activation, development of novel co-culture assays, and analyzing expression. - Assisted in the progression of projects through the developmental pipeline by providing sound experimental results to cross-functional project teams. - Mentored two undergraduate summer interns. Show less Design, execute, and analyze in vitro studies to validate the biology of candidate drug targets in the therapeutic area of autoimmunity and inflammation in the Cellular Immunology Department. - Performed studies using antibodies or other protein-fusions targeting a range of membrane and soluble targets on various immune cell types with primary focus on protein therapeutics, including: T-cell, macrophage, dendritic, and monocyte cell assays looking for the modulation of activation… Show more Design, execute, and analyze in vitro studies to validate the biology of candidate drug targets in the therapeutic area of autoimmunity and inflammation in the Cellular Immunology Department. - Performed studies using antibodies or other protein-fusions targeting a range of membrane and soluble targets on various immune cell types with primary focus on protein therapeutics, including: T-cell, macrophage, dendritic, and monocyte cell assays looking for the modulation of activation, development of novel co-culture assays, and analyzing expression. - Assisted in the progression of projects through the developmental pipeline by providing sound experimental results to cross-functional project teams. - Mentored two undergraduate summer interns. Show less

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Research Associate
      • Oct 2007 - Jan 2010

      Developed and incorporated assays into successful projects: optimized the generation of human myeloid dendritic cells (mDC) and successfully monitored the effects of vaccine adjuvants on mDC maturation by flow cytometry. - Collaborated with a team of scientists and clinical coordinators to start international clinical trials: planned the methods, supplies, and reagents for immunology collection and processing and trained site laboratory personnel. - Certified in Phlebotomy and regularly… Show more Developed and incorporated assays into successful projects: optimized the generation of human myeloid dendritic cells (mDC) and successfully monitored the effects of vaccine adjuvants on mDC maturation by flow cytometry. - Collaborated with a team of scientists and clinical coordinators to start international clinical trials: planned the methods, supplies, and reagents for immunology collection and processing and trained site laboratory personnel. - Certified in Phlebotomy and regularly performed blood draws for experiments. - Directed the activities of a Research Assistant, balancing priorities between multiple projects. - Oversaw the maintenance and repair of flow cytometers and trained co-workers on usage. Show less Developed and incorporated assays into successful projects: optimized the generation of human myeloid dendritic cells (mDC) and successfully monitored the effects of vaccine adjuvants on mDC maturation by flow cytometry. - Collaborated with a team of scientists and clinical coordinators to start international clinical trials: planned the methods, supplies, and reagents for immunology collection and processing and trained site laboratory personnel. - Certified in Phlebotomy and regularly… Show more Developed and incorporated assays into successful projects: optimized the generation of human myeloid dendritic cells (mDC) and successfully monitored the effects of vaccine adjuvants on mDC maturation by flow cytometry. - Collaborated with a team of scientists and clinical coordinators to start international clinical trials: planned the methods, supplies, and reagents for immunology collection and processing and trained site laboratory personnel. - Certified in Phlebotomy and regularly performed blood draws for experiments. - Directed the activities of a Research Assistant, balancing priorities between multiple projects. - Oversaw the maintenance and repair of flow cytometers and trained co-workers on usage. Show less

    • United States
    • Research Services
    • 200 - 300 Employee
    • Lab Manager
      • 2001 - 2007

      Managed day-to-day laboratory operations as well as performed publication-quality research in Type-1 Diabetes. - Performed studies on Type-1 diabetic patient samples using MHC Class II tetramer staining and T-cell cloning techniques to characterize diabetic specific T-cells. - Authored papers: prepared figures for manuscript and assisted in the composition. - Served as point-person for an external collaboration, including coordination of sample shipments and assay technology… Show more Managed day-to-day laboratory operations as well as performed publication-quality research in Type-1 Diabetes. - Performed studies on Type-1 diabetic patient samples using MHC Class II tetramer staining and T-cell cloning techniques to characterize diabetic specific T-cells. - Authored papers: prepared figures for manuscript and assisted in the composition. - Served as point-person for an external collaboration, including coordination of sample shipments and assay technology transfer. - Supervised 2 laboratory technicians and oversaw laboratory operations, including equipment purchasing, human blood processing, reagent purchasing, safety training, and allocating laboratory space. Show less Managed day-to-day laboratory operations as well as performed publication-quality research in Type-1 Diabetes. - Performed studies on Type-1 diabetic patient samples using MHC Class II tetramer staining and T-cell cloning techniques to characterize diabetic specific T-cells. - Authored papers: prepared figures for manuscript and assisted in the composition. - Served as point-person for an external collaboration, including coordination of sample shipments and assay technology… Show more Managed day-to-day laboratory operations as well as performed publication-quality research in Type-1 Diabetes. - Performed studies on Type-1 diabetic patient samples using MHC Class II tetramer staining and T-cell cloning techniques to characterize diabetic specific T-cells. - Authored papers: prepared figures for manuscript and assisted in the composition. - Served as point-person for an external collaboration, including coordination of sample shipments and assay technology transfer. - Supervised 2 laboratory technicians and oversaw laboratory operations, including equipment purchasing, human blood processing, reagent purchasing, safety training, and allocating laboratory space. Show less

    • Biotechnology
    • 1 - 100 Employee
    • Quality Control Analyst
      • Apr 2000 - Jun 2001

      Clinical pharmaceutical testing group team member carrying out cGMP assays for Enbrel and other protein-based drugs. - Transferred assays from the development group into Quality Control, including assay qualification, SOP preparation, and validation. Clinical pharmaceutical testing group team member carrying out cGMP assays for Enbrel and other protein-based drugs. - Transferred assays from the development group into Quality Control, including assay qualification, SOP preparation, and validation.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Technologist
      • Jul 1998 - Apr 2000

Education

  • Mount Holyoke College
    BA, Biochemistry
    1994 - 1998
  • University of Washington
    Certificate, Tableau Visual Analytics
    2015 - 2016

Community

You need to have a working account to view this content. Click here to join now