Experience

ATLANTIC BONE SCREEN

• France
• Biotechnology
• 1 - 100 Employee

• Chef de projet

  • Mar 2023 - Present



ERBC (European Research Biology Center)

• France
• Biotechnology
• 100 - 200 Employee

• Directeur d'études en pharmacologie et toxicologie

  • Oct 2021 - Mar 2023

  Baugy, Centre-Val de Loire, France Etudes MTD/DRF, PK/PD, Irwin, respiration, hERG patch clamp, télémétrie, contrôle de lots. Membre de la Structure chargée du Bien-Etre des Animaux (SBEA).



Institut Pasteur de Lille

• France
• Research Services
• 100 - 200 Employee

• Post doctoral Position in the J&K laboratory, INSERM U1011

  • Jan 2021 - Oct 2021

  Lille Study of FAT10 and PPARalpha role in NASH progression



Institut Pasteur de Lille

• France
• Research Services
• 100 - 200 Employee

• Post Doctoral Position (29 months)

  • May 2018 - Oct 2020

  Lille The aim of the study is to investigate the impact of smoking cigarette and unhealthy diet (SCUD) on pulmonary, intestinal and metabolic homeostasis in mice and to identify specific signatures and biomarkers. For that, function and immunologic parameters were studied as well as transcriptomic, metagenomics and metabolomics analysis. Data obtained will allow to identify targets for the prevention, the diagnostic and the treatment of pulmonary, intestinal and metabolic disorders due to the SCUD… Show more The aim of the study is to investigate the impact of smoking cigarette and unhealthy diet (SCUD) on pulmonary, intestinal and metabolic homeostasis in mice and to identify specific signatures and biomarkers. For that, function and immunologic parameters were studied as well as transcriptomic, metagenomics and metabolomics analysis. Data obtained will allow to identify targets for the prevention, the diagnostic and the treatment of pulmonary, intestinal and metabolic disorders due to the SCUD and to improve the quality of life of obese chronic obstructive pulmonary disease (COPD) patients. Show less



INSERM

• France
• Research Services
• 700 & Above Employee

• PhD student in Neuropharmacology of Pain

  • Oct 2014 - Dec 2017

  The objective of my PhD was to characterize functional implication of Cav2.3 calcium channels in two types of chronic pain: visceral and somatic. We have developed a murine model of colonic hypersensitivity associated with low grade inflammation, two symptomatic features close to the symptomatology found in most patients suffering from irritable bowel syndrome (IBS) or with diseases inflammatory bowel disease (IBD) during remission periods. Concerning the somatic pain, we used two murine models… Show more The objective of my PhD was to characterize functional implication of Cav2.3 calcium channels in two types of chronic pain: visceral and somatic. We have developed a murine model of colonic hypersensitivity associated with low grade inflammation, two symptomatic features close to the symptomatology found in most patients suffering from irritable bowel syndrome (IBS) or with diseases inflammatory bowel disease (IBD) during remission periods. Concerning the somatic pain, we used two murine models of inflammatory pain, one with subacute inflammation and another with persistent inflammation. In these different models, pharmacological and genetic inhibitions of the Cav3.2 were applied to demonstrate and localize their implication in chronic pain. Finally, with a translational research approach, we evaluated the effect of ethosuximide (ETX), a T-channel blocker, clinically used in the treatment of epilepsy. We have described an analgesic effect of the latter in both models studied as well as an anti-inflammatory action. These results constitute a pre-clinical proof of concept for a clinical efficacy evaluation of ETX in a context of visceral pain or somatic inflammatory diseases. Altogether, these results provide new insight into the involvement of Cav3.2 channels in chronic pain and allow us to propose these channels as targets of interest for the development of new therapeutic strategies to relieve patients. Show less



INSERM

• France
• Research Services
• 700 & Above Employee

• Master 2 degree's internship

  • Jan 2014 - Jun 2014

  Clermont-Ferrand, FRANCE Implementation of a research project investigating the role of the voltages-dependent calcium ion channels Cav3.2 in chronic pain.



Monash University

• Australia
• Higher Education
• 700 & Above Employee

• Master 1 degree's internship

  • Jun 2013 - Aug 2013

  Melbourne, Australia Preclinical evaluation of the therapeutic efficacy of new treatment on the psychotic symptoms encountered in schizophrenia.