Experience

React4life

• Italy
• Biotechnology Research
• 1 - 100 Employee

• Senior Research Scientist

  • Jan 2023 - Present

  React4life is an italian company, with a patented technology: Multi In Vitro Organ (MIVO), an innovative fluidic bioreactor emulating portions of the human body, to improve the effectiveness of pharmaceutical tests, discover innovative therapeutic approaches, and reduce animal testing. MIVO allows to host and cultivate 3D organoids, tissue models or commercial available human tissues in a fluid-dynamic environment. Several applications are available: oncology, pharma, nutraceutical, cosmetical. Scientific validations prove that it is possible to resemble cell migration phenomena (for the study of tumor metastasis onset) and the diffusion/extravasation of molecules from blood circulation (for drug efficacy testing) . Beyond that, the React4life portfolio currently includes in vitro 3D tumor models (i.e. breast cancer model, neuroblastoma model, ovaric cancer). Show less



Università degli Studi di Genova

• Italy
• Higher Education
• 700 & Above Employee

• Postdoctoral Researcher

  • Dec 2018 - Dec 2022

  - Isolation and characterization of extracellular vesicles from different stem cells populations. - Nano-tagging of extracellular vesicles for tracking in vivo in small and large animal models. - Development of 3D models for extracellular vesicle production. - Development of 3D-printed models for regeneration of cartilage defects. - Generation of new therapeutic cell sources, MSC (hiMSC) and chondrocytes (hiCHO) generated from iPSCs. - Development of extracellular vesicle-based translational regenerative therapies using small and large animal models. Show less



Università degli Studi di Genova

• Italy
• Higher Education
• 700 & Above Employee

• PHD Student

  • Nov 2015 - Oct 2018

  - Application of stem cells-derived extracellular vesicles for cartilage regeneration. - Biomaterials and stem cells applied to cartilage and bone regeneration / endochondral ossification (in vivo & in vitro). - Tissue engineering approaches to study breast cancer bone metastases (in vitro & in vivo). - Application of stem cells-derived extracellular vesicles for cartilage regeneration. - Biomaterials and stem cells applied to cartilage and bone regeneration / endochondral ossification (in vivo & in vitro). - Tissue engineering approaches to study breast cancer bone metastases (in vitro & in vivo).



Università del Salento

• Italy
• Higher Education
• 500 - 600 Employee

• Student Internship

  • Mar 2014 - Dec 2014

  Cell culture strategies applied to the regeneration of myelin sheat. Cell culture strategies applied to the regeneration of myelin sheat.