Eleanor Eiffe

Software Engineer at Evidentli
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Location
Greater Sydney Area, AU

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Experience

    • Australia
    • Software Development
    • 1 - 100 Employee
    • Software Engineer
      • Sep 2021 - Present

      I use Python and React to build tools for standardising and analysing complex healthcare data. I specialise in translating AI solutions into the next generation of Evidentli products. I use Python and React to build tools for standardising and analysing complex healthcare data. I specialise in translating AI solutions into the next generation of Evidentli products.

    • Australia
    • Higher Education
    • 700 & Above Employee
    • Senior Research Officer
      • Oct 2018 - Sep 2021

      I joined the Cellular and Genetic Medicine Unit (CGMU) to manage a CRC-P funded drug development program conducted in collaboration with industry partner TroBio Therapeutics. I have planned, implemented, and managed a medicinal chemistry campaign which has developed two weakly potent screening hits into patentable compounds with superior biological activity and improved physicochemical properties. To achieve this, I have: • Designed more than 400 novel tropomyosin-targeting compounds via in silico docking and de novo design with tropomyosin homology models; • Identified ligands for tropomyosin isoforms via high throughput virtual screening of commercial compound libraries; • Developed synthetic routes for novel compounds and managed the external chemistry team conducting compound synthesis; • Established and developed relationships with CRC-P subcontractors providing chemistry, biology, and speciality software services; • Collaborated with CGMU heads to develop a screening and lead selection strategy to identify compounds with the desired biological activity and favourable druglike properties; and • Coordinated with internal and external stakeholders to communicate project priorities and ensure that deadlines are met. Show less

    • Australia
    • Biotechnology Research
    • 1 - 100 Employee
    • Drug Discovery Program Manager
      • Nov 2013 - Dec 2017

      I joined this oncology drug development company to manage the hit-to-lead development phase of a novel cancer treatment technology. While drug discovery remained my primary focus, my role expanded to encompass intellectual property, scale-up and manufacturing, formulation development and preparation of regulatory submissions. During this time, I: • Designed small molecule libraries for drug discovery projects and managed the external team conducting chemical synthesis; • Ensured the on-time delivery of high quality GMP API while on-site at a contract manufacturing organisation; • Prepared Chemistry, Manufacturing and Controls sections of a successful IND submission and IND update to the US FDA; • Prepared six patent applications and worked with patent attorneys to manage Kazia’s IP portfolio; and • Presented at national and international medicinal chemistry conferences. Show less

    • Australia
    • Research Services
    • 1 - 100 Employee
      • Nov 2012 - Nov 2013

      I worked with both the School of Chemistry and the School of Physics at UNSW to help each school overhaul their systems for managing Health & Safety (HS) documentation. During this time, I:• Ensured that both Schools passed their respective HS audits;• Prepared, reviewed and established systems for the management of HS documents; and• Implemented UNSW HS Policy, ensuring that the Schools complied with NSW law and the relevant Australian Standards.

      • Jun 2012 - Nov 2013

      After submitting my thesis, I worked with my PhD supervisor as a part-time research associate. This role allowed me to build on the skills I developed during my PhD research via:• Mentoring undergraduate, Honours and PhD students;• Preparation of grant applications and research papers; and• Synthesis and characterisation of novel small molecules

    • United States
    • Pharmaceutical Manufacturing
    • 1 - 100 Employee
    • Administrative Assistant/Laboratory Technician
      • Aug 2011 - Feb 2012

      During my PhD studies, I was employed on a short-term basis to assist with preparations for an external audit. This involved: • Reviewing and updating documents to meet GMP standards; • Processing and archiving the results of Quality Control analyses; and • Timely analysis of raw materials, finished products, and product packaging following approved methods. During my PhD studies, I was employed on a short-term basis to assist with preparations for an external audit. This involved: • Reviewing and updating documents to meet GMP standards; • Processing and archiving the results of Quality Control analyses; and • Timely analysis of raw materials, finished products, and product packaging following approved methods.

    • India
    • Mining
    • Scientist
      • Jul 2004 - Feb 2009

      I joined this pharmaceutical company as a research and development chemist in a lab-based role that encompassed: • Design and synthesis of novel drug candidates; • Process development and scale-up for lead compounds; and • Training and mentoring of junior laboratory staff. I joined this pharmaceutical company as a research and development chemist in a lab-based role that encompassed: • Design and synthesis of novel drug candidates; • Process development and scale-up for lead compounds; and • Training and mentoring of junior laboratory staff.

Education

  • UNSW Australia
    Doctor of Philosophy (Ph.D.), Organic Chemistry
    2006 - 2012
  • Flinders University
    Bachelor of Science (BSc) (Honours), Organic Chemistry
    2003 - 2003
  • Flinders University
    Bachelor of Technology (B.Tech.), Forensic and Analytical Chemistry
    2000 - 2002

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