Duy An Le
Undergraduate Researcher at University of California, San Diego - School of Medicine- Claim this Profile
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Vietnamese Native or bilingual proficiency
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English Native or bilingual proficiency
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Spanish Limited working proficiency
Topline Score
Bio
Experience
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UC San Diego School of Medicine
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United States
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Higher Education
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200 - 300 Employee
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Undergraduate Researcher
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Jun 2023 - Present
PI: Karl Wahlin - Designing CRISPRa gene cassettes for stable integration and expression in human stem cells - Activating expression of key transcription factors in retinal development - Comparison efficacy of dCas9, dCpf1, and dCasMini systems to reprogram stem cells PI: Karl Wahlin - Designing CRISPRa gene cassettes for stable integration and expression in human stem cells - Activating expression of key transcription factors in retinal development - Comparison efficacy of dCas9, dCpf1, and dCasMini systems to reprogram stem cells
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UC San Diego
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United States
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Higher Education
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700 & Above Employee
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Undergraduate Research Assistant
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Oct 2020 - Present
PI: Prashant Mali - Engineering AAV tropism by displaying peptides on AAV capsid structure - Utilized machine learning models to predict structures of approximately 50 different peptide-displaying AAV’s at different sites and recorded predicted alignment scores with original AAV’s - Maintained and transfected multiple mammalian cell lines including HEK, Hela, MDMA, A549, and K562 - Worked on building AAV constructs, performing peptide screen, validating hits, analyzing data PI: Prashant Mali - Engineering AAV tropism by displaying peptides on AAV capsid structure - Utilized machine learning models to predict structures of approximately 50 different peptide-displaying AAV’s at different sites and recorded predicted alignment scores with original AAV’s - Maintained and transfected multiple mammalian cell lines including HEK, Hela, MDMA, A549, and K562 - Worked on building AAV constructs, performing peptide screen, validating hits, analyzing data
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MP Biomedicals
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United States
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Biotechnology Research
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400 - 500 Employee
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Research And Development Intern
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Jul 2022 - Sep 2022
- Part of the UCSD Biological Sciences Co-Op Program where students get hands-on work experience with a Life Sciences company and develop professional skills - Developed and optimized a procedural MTS cell viability assay for use in product testing and quality assurance (SoA). - Streamlined the Cell Biology product line page by reorganizing products and designing landing pages for a customer-oriented web interface. - Compared market prices for nearly 200 Cell Biology products to make price suggestions for the following year. - Investigated the efficiency of three different exosome purification procedures as potential implementation in a new product. Show less
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Education
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UC San Diego
Bachelor of Science - BS, Bioengineering and Biomedical Engineering -
Fountain Valley High School
High School Diploma