Duy An Le

Undergraduate Researcher at University of California, San Diego - School of Medicine
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Contact Information
us****@****om
(386) 825-5501
Location
Fountain Valley, California, United States, US
Languages
  • Vietnamese Native or bilingual proficiency
  • English Native or bilingual proficiency
  • Spanish Limited working proficiency

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Experience

    • United States
    • Higher Education
    • 200 - 300 Employee
    • Undergraduate Researcher
      • Jun 2023 - Present

      PI: Karl Wahlin - Designing CRISPRa gene cassettes for stable integration and expression in human stem cells - Activating expression of key transcription factors in retinal development - Comparison efficacy of dCas9, dCpf1, and dCasMini systems to reprogram stem cells PI: Karl Wahlin - Designing CRISPRa gene cassettes for stable integration and expression in human stem cells - Activating expression of key transcription factors in retinal development - Comparison efficacy of dCas9, dCpf1, and dCasMini systems to reprogram stem cells

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • Oct 2020 - Present

      PI: Prashant Mali - Engineering AAV tropism by displaying peptides on AAV capsid structure - Utilized machine learning models to predict structures of approximately 50 different peptide-displaying AAV’s at different sites and recorded predicted alignment scores with original AAV’s - Maintained and transfected multiple mammalian cell lines including HEK, Hela, MDMA, A549, and K562 - Worked on building AAV constructs, performing peptide screen, validating hits, analyzing data PI: Prashant Mali - Engineering AAV tropism by displaying peptides on AAV capsid structure - Utilized machine learning models to predict structures of approximately 50 different peptide-displaying AAV’s at different sites and recorded predicted alignment scores with original AAV’s - Maintained and transfected multiple mammalian cell lines including HEK, Hela, MDMA, A549, and K562 - Worked on building AAV constructs, performing peptide screen, validating hits, analyzing data

    • United States
    • Biotechnology Research
    • 400 - 500 Employee
    • Research And Development Intern
      • Jul 2022 - Sep 2022

      - Part of the UCSD Biological Sciences Co-Op Program where students get hands-on work experience with a Life Sciences company and develop professional skills - Developed and optimized a procedural MTS cell viability assay for use in product testing and quality assurance (SoA). - Streamlined the Cell Biology product line page by reorganizing products and designing landing pages for a customer-oriented web interface. - Compared market prices for nearly 200 Cell Biology products to make price suggestions for the following year. - Investigated the efficiency of three different exosome purification procedures as potential implementation in a new product. Show less

Education

  • UC San Diego
    Bachelor of Science - BS, Bioengineering and Biomedical Engineering
    2020 - 2024
  • Fountain Valley High School
    High School Diploma
    2016 - 2020

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