Dustin Sands
Senior Process Modeler at Ark Biotech- Claim this Profile
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Bio
Experience
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Ark Biotech
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Process Modeler
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Jul 2022 - Present
-Created simulation framework for bioreactor and cellular models. Supports creation of models, analysis of data, and running of Digital Twins in easily modular form -Analyzed, modeled, and reported on client data that yielded signficant yield increases on cultured meat bioprocesses -Simulated and compared various bioreactor modes and processes in support of technology selection and technoeconomic analyses (e.g, fed-batch vs perfusion) -Created simulation framework for bioreactor and cellular models. Supports creation of models, analysis of data, and running of Digital Twins in easily modular form -Analyzed, modeled, and reported on client data that yielded signficant yield increases on cultured meat bioprocesses -Simulated and compared various bioreactor modes and processes in support of technology selection and technoeconomic analyses (e.g, fed-batch vs perfusion)
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Takeda
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Japan
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Pharmaceutical Manufacturing
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700 & Above Employee
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Machine Learning and Manufacturing Data Automation Scientist / Research Investigator, Cell Therapy
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Dec 2020 - Jul 2022
-Technical Lead on entire-process simulation tool that models operational timings and quality attributes with applications in process optimization, supply chain forecasting, and operational scheduling -Core team member of In-Silico CMC and contributor to global In-Silico CMC Playbook -Modeling Lead for upstream predictive control project utilizing a digital twin -Aided and supported in interfacing between process development and digitalization teams -Technical Lead on entire-process simulation tool that models operational timings and quality attributes with applications in process optimization, supply chain forecasting, and operational scheduling -Core team member of In-Silico CMC and contributor to global In-Silico CMC Playbook -Modeling Lead for upstream predictive control project utilizing a digital twin -Aided and supported in interfacing between process development and digitalization teams
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None
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700 & Above Employee
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Researcher
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Mar 2020 - Dec 2020
Studying and developing machine learning methods and how they can be applied to process development Created an Upstream Cell Culture Simulator; https://portfolio.dustinsands.com/cc-sim For some current projects, see https://github.com/DustinSands?tab=repositories Studying and developing machine learning methods and how they can be applied to process development Created an Upstream Cell Culture Simulator; https://portfolio.dustinsands.com/cc-sim For some current projects, see https://github.com/DustinSands?tab=repositories
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Boehringer Ingelheim
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Germany
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Pharmaceutical Manufacturing
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700 & Above Employee
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Scientist I
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Jan 2019 - Mar 2020
-Characterized and assessed new technologies for use in developing a next generation manufacturing platform -Developed process analytical technology for use in controlling process parameters -Lead, designed, analyzed, and presented experiments primarily using lab-scale perfusion systems Worked with: SUBs and reusable bioreactors at 2L to 1000L scales, cGMP, shake flasks, Python, Tensorflow, and Trubio, amongst others -Characterized and assessed new technologies for use in developing a next generation manufacturing platform -Developed process analytical technology for use in controlling process parameters -Lead, designed, analyzed, and presented experiments primarily using lab-scale perfusion systems Worked with: SUBs and reusable bioreactors at 2L to 1000L scales, cGMP, shake flasks, Python, Tensorflow, and Trubio, amongst others
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BioCurious
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United States
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Biotechnology Research
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1 - 100 Employee
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Volunteer
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Jan 2017 - Mar 2020
Working on the Real Vegan Cheese community project: -Attempts to make real cheese from entirely vegan sources by synthesizing milk proteins and growing cultures from vegan food sources Working on the Real Vegan Cheese community project: -Attempts to make real cheese from entirely vegan sources by synthesizing milk proteins and growing cultures from vegan food sources
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UCL
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London, United Kingdom
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Masters Student
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Sep 2015 - Mar 2016
Responsible for the "Development of an analytical method for the online detection of biocatalyst reaction rates in continuous-flow synthesis." Responsible for the "Development of an analytical method for the online detection of biocatalyst reaction rates in continuous-flow synthesis."
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University of Southampton
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United Kingdom
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Higher Education
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700 & Above Employee
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Researcher, Computational Chemistry
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Jul 2015 - Sep 2015
Worked with superclusters to simulated charged amino acids in a DOPC membrane using a dual-resolution model (ELBA) in LAMMPS. Visualized and interpreted results in order to give model feedback. Created PMF plots. Worked with superclusters to simulated charged amino acids in a DOPC membrane using a dual-resolution model (ELBA) in LAMMPS. Visualized and interpreted results in order to give model feedback. Created PMF plots.
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Education
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UCL
Master’s Degree, Chemical with Biochemical Engineering