Dustin Sands

Senior Process Modeler at Ark Biotech
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Contact Information
us****@****om
(386) 825-5501
Location
Cambridge, Massachusetts, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Process Modeler
      • Jul 2022 - Present

      -Created simulation framework for bioreactor and cellular models. Supports creation of models, analysis of data, and running of Digital Twins in easily modular form -Analyzed, modeled, and reported on client data that yielded signficant yield increases on cultured meat bioprocesses -Simulated and compared various bioreactor modes and processes in support of technology selection and technoeconomic analyses (e.g, fed-batch vs perfusion) -Created simulation framework for bioreactor and cellular models. Supports creation of models, analysis of data, and running of Digital Twins in easily modular form -Analyzed, modeled, and reported on client data that yielded signficant yield increases on cultured meat bioprocesses -Simulated and compared various bioreactor modes and processes in support of technology selection and technoeconomic analyses (e.g, fed-batch vs perfusion)

    • Japan
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Machine Learning and Manufacturing Data Automation Scientist / Research Investigator, Cell Therapy
      • Dec 2020 - Jul 2022

      -Technical Lead on entire-process simulation tool that models operational timings and quality attributes with applications in process optimization, supply chain forecasting, and operational scheduling -Core team member of In-Silico CMC and contributor to global In-Silico CMC Playbook -Modeling Lead for upstream predictive control project utilizing a digital twin -Aided and supported in interfacing between process development and digitalization teams -Technical Lead on entire-process simulation tool that models operational timings and quality attributes with applications in process optimization, supply chain forecasting, and operational scheduling -Core team member of In-Silico CMC and contributor to global In-Silico CMC Playbook -Modeling Lead for upstream predictive control project utilizing a digital twin -Aided and supported in interfacing between process development and digitalization teams

    • 700 & Above Employee
    • Researcher
      • Mar 2020 - Dec 2020

      Studying and developing machine learning methods and how they can be applied to process development Created an Upstream Cell Culture Simulator; https://portfolio.dustinsands.com/cc-sim For some current projects, see https://github.com/DustinSands?tab=repositories Studying and developing machine learning methods and how they can be applied to process development Created an Upstream Cell Culture Simulator; https://portfolio.dustinsands.com/cc-sim For some current projects, see https://github.com/DustinSands?tab=repositories

    • Germany
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Scientist I
      • Jan 2019 - Mar 2020

      -Characterized and assessed new technologies for use in developing a next generation manufacturing platform -Developed process analytical technology for use in controlling process parameters -Lead, designed, analyzed, and presented experiments primarily using lab-scale perfusion systems Worked with: SUBs and reusable bioreactors at 2L to 1000L scales, cGMP, shake flasks, Python, Tensorflow, and Trubio, amongst others -Characterized and assessed new technologies for use in developing a next generation manufacturing platform -Developed process analytical technology for use in controlling process parameters -Lead, designed, analyzed, and presented experiments primarily using lab-scale perfusion systems Worked with: SUBs and reusable bioreactors at 2L to 1000L scales, cGMP, shake flasks, Python, Tensorflow, and Trubio, amongst others

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Volunteer
      • Jan 2017 - Mar 2020

      Working on the Real Vegan Cheese community project: -Attempts to make real cheese from entirely vegan sources by synthesizing milk proteins and growing cultures from vegan food sources Working on the Real Vegan Cheese community project: -Attempts to make real cheese from entirely vegan sources by synthesizing milk proteins and growing cultures from vegan food sources

  • UCL
    • London, United Kingdom
    • Masters Student
      • Sep 2015 - Mar 2016

      Responsible for the "Development of an analytical method for the online detection of biocatalyst reaction rates in continuous-flow synthesis." Responsible for the "Development of an analytical method for the online detection of biocatalyst reaction rates in continuous-flow synthesis."

    • United Kingdom
    • Higher Education
    • 700 & Above Employee
    • Researcher, Computational Chemistry
      • Jul 2015 - Sep 2015

      Worked with superclusters to simulated charged amino acids in a DOPC membrane using a dual-resolution model (ELBA) in LAMMPS. Visualized and interpreted results in order to give model feedback. Created PMF plots. Worked with superclusters to simulated charged amino acids in a DOPC membrane using a dual-resolution model (ELBA) in LAMMPS. Visualized and interpreted results in order to give model feedback. Created PMF plots.

Education

  • UCL
    Master’s Degree, Chemical with Biochemical Engineering
    2012 - 2016

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