Dr. Nicole Paland

Head of Product Development at Minerva Biolabs
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Contact Information
us****@****om
(386) 825-5501
Location
Berlin, Berlin, Germany, DE
Languages
  • German Native or bilingual proficiency
  • English Full professional proficiency
  • Hebrew Professional working proficiency

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Bio

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Credentials

  • Drug Development
    University of California, San Diego
    Sep, 2020
    - Nov, 2024
  • International Good Clinical Practice
    PharmaLessons
    Feb, 2020
    - Nov, 2024
  • BWL für Naturwissenschaftlicher
    Pharmaakademie

Experience

  • Minerva Biolabs GmbH
    • Germany
    • Biotechnology Research
    • 1 - 100 Employee
    • Head of Product Development
      • Sep 2022 - Present

      Verantwortung zur Planung, Durchführung, Steuerung und Verwertung von Entwicklungsarbeiten von der Anforderungsanalyse bis hin zu den Prototypen unter Beachtung des Qualitätsmanagementsystems des Unternehmens nach den gültigen DIN EN ISO 13485 und ISO 9001 sowie IVDR.Weitere Aufgaben: • Enge kreative Zusammenarbeit mit der Geschäftsführung• Fachliche und strategische Planung und Leitung von Ressourcen und Prozessen für die Entwicklung neuer Produkte und dem Produkt Lifecycle Management existierender Produkte hinsichtlich Kosten, Qualität und Terminen der Time to Market im Entwicklungsprozess – von der Strategie bis zum Ende des Lebenszyklus• Etablierung von Projekten zur Entwicklung neuer innovativer Produkte und Produktverbesserungen• Kollaboration mit internen und externen Stakeholdern Schnittstelle aller beteiligten Ressourcen, die für die Produktentwicklung nötig sind, d. h. zwischen Geschäftsleitung, Marketing, Produktion und Vertrieb• Teamaufbau und Teamleitung der Produktentwicklung sowie motivierende und zielorientierte Führung des Teams bestehend aus Projektleitern, Wissenschaftlichen Mitarbeitern und Technischen Assistenten• Proaktives Managen von Änderungen im Projektumfang und Identifizierung potentieller Risiken• Sicherstellung der Einhaltung aller gesetzlichen Bestimmungen im Aufgabenbereich Produktentwicklung sowie aller Vorgaben aus dem Qualitätsmanagement• Verbesserung unseres Qualitätsmanagementsystems• betriebliche Aus- und Weiterbildung• Betreuung von Praktikanten, Bachelor- und Masterstudenten sowie studentischen Hilfskräften Show less

    • Project Leader
      • Mar 2021 - Present

      Product development of NAT-based kits for the detection of microbial contamination

  • Self-employed
    • Medical and Scientific Writer
      • Jul 2018 - Sep 2022

      - Founder and Owner - Writing, Editing and Proofreading - Authoring and supporting the writing and submission of reviews and manuscripts for the peer-reviewed process - Medical and Scientific Writing, Editing and Proofreading - Support review and submission of investigator-initiated research and ethical proposals - Detail-oriented review of different document types and input for improvement - Literature research and compilation - Project management inclusive client communication and organization of internal meetings and compliance to the required standards - Build Customer and Business Relationships - Business Development and Marketing Strategies - Cooperation with Davidson-Institute for Education at the Weizmann Institute of Science (Translation Project for an Educational Website) - Cooperation with the Cannabis Research and Innovation Center at Rambam Health Care Center in Haifa, Israel Show less

  • Rambam Health Care Campus
    • Israel
    • Hospitals and Health Care
    • 700 & Above Employee
    • Administrative Manager and Scientific Coordinator at Medical Cannabis Research & Innovation Center
      • Jul 2020 - Mar 2021

      - Authoring and supporting the writing and submission of reviews and manuscripts for the peer-reviewed process - Support review and submission of investigator-initiated research and ethical proposals - Adhere to the national and local requirements of the Ministry of Health - Detail-oriented review of different document types and input for improvement - Literature research and compilation - Project management inclusive client communication and organization of internal meetings and compliance to the required standards Show less

  • University of Haifa Faculty of Human Biology Cancer Research
    • Haifa Area, Israel
    • Senior Research Scientist
      • Sep 2016 - May 2018

      Role of mutual regulation between ARTS and p53 in promoting apoptosis and cancer prevention - Planning and implementing projects -Team work - Supervision of students Role of mutual regulation between ARTS and p53 in promoting apoptosis and cancer prevention - Planning and implementing projects -Team work - Supervision of students

  • Rappaport Faculty of Medicine, Parkinson Research
    • Haifa, Israel
    • Senior Research Scientist
      • Nov 2014 - Aug 2016

      Investigated the role of Gaucher's Disease as a risk factor for the development of idiopathic Parkinson's Disease • Established the method of CRISPR and Real Time PCR in the lab Investigated the role of Gaucher's Disease as a risk factor for the development of idiopathic Parkinson's Disease • Established the method of CRISPR and Real Time PCR in the lab

  • Rappaport Faculty of Medicine Lipid Research Laboratory Atherosclerosis, Metabolic Diseases
    • Haifa
    • Senior Postdoctoral Researcher
      • Sep 2011 - Aug 2014

      • Investigated the function of the urokinase-type plasminogen activator (uPA)/urokinase receptor (uPAR) system for the development and progression of atherosclerosis, non-alcoholic fatty liver disease and diabetes using uPAR knock-out mice and in vitro cell culture approaches. - I revealed that the uPA/uPAR system accelerates the differentiation of monocytes to macrophages mediated by G1 arrest, downregulation of G2/S phase and inhibition of PMA-induced cell death. - I found out that the uPA/uPAR system stimulates triglyceride synthesis in Huh7 hepatoma cells via p38-dependent upregulation of DGAT2. • Planned, implemented and finished four projects successfully with two projects published in international peer-reviewed journals • Supervised one medical student successfully through its project resulting in a publication in peer-reviewed journal • Publication of one book chapter in the book Role of Proteases in Cellular Dysfunction, Advances in Biochemistry in Health and Disease • Oral and poster presentations at international conferences • Closely worked together with colleagues resulting in two publications in peer-reviewed international journals Show less

  • Rappaport Faculty of Medicine
    • Haifa Area, Israel
    • Postdoctoral Researcher
      • Sep 2009 - Aug 2011

      Investigated the impact of the adenoviral protein E4orf4 on the progression of a viral infection using ChromatinImmunoprecipitation (ChIP) Technology and on the microenvironment of infected cells in respect to the apoptotic behaviour of surrounding cells • Established and introduced the ChIP Technology and Real Time PCR to the lab Investigated the impact of the adenoviral protein E4orf4 on the progression of a viral infection using ChromatinImmunoprecipitation (ChIP) Technology and on the microenvironment of infected cells in respect to the apoptotic behaviour of surrounding cells • Established and introduced the ChIP Technology and Real Time PCR to the lab

  • Weizmann Institute of Science Cancer Research
    • Rehovot Area, Israel
    • Postdoctoral Researcher
      • Jan 2007 - Jun 2009

      • Using an in vitro 2-D model of prostate cancer cells I revealed that cancer associated fibroblasts (CAFs) change the cell microenvironment in a way which helps cancer progression while normal associated fibroblasts (NAFs) act in a cancer-inhibiting fashion through the differential release of IL-6 or TNFalpha. • Using an in vitro 2-D model of prostate cancer cells I revealed that cancer associated fibroblasts (CAFs) change the cell microenvironment in a way which helps cancer progression while normal associated fibroblasts (NAFs) act in a cancer-inhibiting fashion through the differential release of IL-6 or TNFalpha.

  • Max Planck Institute for Infection Biology
    • Research Services
    • 1 - 100 Employee
    • Postdoctoral Researcher
      • Sep 2005 - Jan 2007

      Investigated the regulation of TNFR1 in cells infected with Chlamydia trachomatis and its role in maintaining a successful infection. I could show that C. trachomatis down regulated TNFR1 on the surface thereby circumventing the actions of the host cell's immune system.

    • Researcher PhD Candidate
      • 2001 - 2006

      Dissertation for Dr. rer. nat. (equivalent DSc.), awarded with Magna Cum Laude, 2001 – 2006Department of Molecular Biology, Laboratory of Prof. Dr. Thomas Rudel Max Planck Institute for Infection Biology, Berlin, Germany• Thesis: Characterization of the apoptotic factors in Chlamydia trachomatis and Chlamydophila pneumoniae infected epithelial and endothelial cells- Managed and implemented this project and revealed that NF-kappaB and Inhibitor of Apoptosis Proteins (IAPs) are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniaehttp://www.ncbi.nlm.nih.gov/pubmed/17069460http://www.ncbi.nlm.nih.gov/pubmed/16984419 Show less

  • Max Planck Institute for Molecular Genetics
    • Diploma Thesis in the department of Prof. Ropers in the working group of Prof. Wolfgang Berger
      • Apr 2000 - Feb 2001

      Characterized the location of the gene product of the RP2 (retinopathia pigmentosa) gene and its disease-promoting mutations in mammalian cells and their influence on disease outcome by microscopy. http://hmg.oxfordjournals.org/content/10/11/1177.abstract Characterized the location of the gene product of the RP2 (retinopathia pigmentosa) gene and its disease-promoting mutations in mammalian cells and their influence on disease outcome by microscopy. http://hmg.oxfordjournals.org/content/10/11/1177.abstract

  • Max Planck Institute for Infection Biology
    • Research Services
    • 1 - 100 Employee
    • Undergraduate Assistent
      • Jan 1996 - Jan 1998

      Max Planck Institute for Molecular Plant Physiology, Potsdam-Golm, Germany, Department Molecular Physiology, Prof. Dr. Lothar Willmitzer Work: I generated plasmid constructs for the detection of transformed mitochondria of upper plants Max Planck Institute for Molecular Plant Physiology, Potsdam-Golm, Germany, Department Molecular Physiology, Prof. Dr. Lothar Willmitzer Work: I generated plasmid constructs for the detection of transformed mitochondria of upper plants

Education

  • Max Planck Institute of Infection Biology/Humboldt University of Berlin
    Doctor of Natural Sciences, Infection Biology
  • University of Potsdam
    Diploma, Biochemistry
    1996 - 2001
  • University College London
    Molecular Biology
    1995 - 1996
  • University of Potsdam
    Pre-Diploma, Biochemistry
    1993 - 1995

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