Dr. Dattatry S. Bhosale

Scientific Researcher at Mendel University in Brno
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Contact Information
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(386) 825-5501
Location
Brno, South Moravia, Czechia, CZ

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Experience

    • Czechia
    • Higher Education
    • 300 - 400 Employee
    • Scientific Researcher
      • Sep 2022 - Present

    • Czechia
    • Higher Education
    • 300 - 400 Employee
    • Postdoctoral Research Fellow
      • Jul 2018 - Present

    • Czechia
    • Food and Beverage Manufacturing
    • 1 - 100 Employee
    • Postdoctoral Researcher
      • Apr 2018 - Aug 2022

      Design and synthesis of diphyllin analogs for antiviral studies, and on the design and creation of next-generation lipid-based nanoparticles for functional delivery of nucleic acid to liver cells in vivo. Also prepared advanced liver-cell receptors-specific targetting ligands involving N-GalNAc, plus polyethylene glycol derivatives and lipids, all for the assembly and formulation of LNPs by means of a modular, click chemistry. The national collaboration work with the Veterinary Research institute in Brno, the University of Pardubice in Pardubice city, and Mendel University in Brno, Czech Republic. International collaboration work with the University of Salzburg in Austria and also Shanghai Jiao Tong University in China. Show less

    • Czechia
    • Higher Education
    • 300 - 400 Employee
    • Ph.D.
      • Nov 2011 - Aug 2017

      ACHIEVEMENT in Ph.D. STUDIES Thesis title: “Selected pyridine derivatives immobilized on colloidal nanosystems for asymmetric Henry reaction and drug delivery application” 1. “Magnetically recoverable catalyst for the asymmetric Henry reaction based on a substituted imidazolidine-4-one copper(II) complex supported by Fe3O4@SiO2 nanoparticles” Dattatry S. Bhosale, Pavel Drabina, Miloslav Kincl, Milan Vlček, Miloš Sedlák, Tetrahedron: Asymmetry, 2015, 26, 1300–1306. 2. “Henry reaction catalyzed by recoverable enantioselective catalysts based on copper(II) complexes of α-methoxypoly(ethylene glycol)-b-poly(L-glutamic acid) and imidazolidine-4-one ligands” Dattatry S. Bhosale, Pavel Drabina, Jiří Palarčík, Jiří Hanusek, Miloš Sedlák, Tetrahedron: Asymmetry, 2014, 25, 334–339. [Highlighted in SYNFACTS, 2014, 10(6), 0655]. 3. “Synthesis and characterization of magnetic nanoparticles Fe3O4@SiO2 decorated with amino groups” Lydie Harmand, Dattatry Bhosale, Ludvík Beneš, Jiří Palarčík, Andréa Kalendová, Miloš Sedlák, Scientific papers of The University of Pardubice, Series A 20. 2014, 191-207. 4. “Synthesis and characterization of a pH-sensitive conjugate of isoniazid with Fe3O4@SiO2 magnetic nanoparticles” Miloš Sedlák, Dattatry S. Bhosale, Ludvík Beneš, Jiří Palarčík, Andrea Kalendová, Karel Královec, Aleš Imramovský, Bioorg. Med. Chem. Lett., 2013, 23, 4692–4695. Show less

    • Research Services
    • 700 & Above Employee
    • Project Assistant
      • Sep 2010 - Sep 2011

      Project Assistant at National Chemical Laboratory, Division of Organic Chemistry, Pune, India. During this period, I have worked on “Development of novel antifungal agents including hybrid molecules”, under the supervision of Dr. Hanumant B. Borate (Sci-F) ACHIEVEMENT in Project Assistant: 1 “One-pot synthesis of 4-alkyl-3-aryl-2,6-dicyanoanliline and their use in the synthesis of highly functionalized 2,3,5,6,7- and 2,3,4,5,7-substituted indoles” Sangmeshwar P. Sawargave, Ananada S. Kudale, Jaydeep V. Deore, Dattatry S. Bhosale, Jaisingh M. Divse, Subhash P. Chavan, Hanumant B. Borate, Tetrahedron Lett., 2011, 52, 5491–5493. 2 “One-pot synthesis of 2,4,5-trisubstituted imidazoles using MoO3/SiO2 an efficient and recyclable catalyst” Sidhanath V. Bhosale, Mohan B. Kalyankar, Santosh V. Nalage, Dattatry S. Bhosale, Swati L. Pandhare, Trupti V. Kotbagi, Shubhangi B. Umbarkar, Mohan K. Dongare, Synth. Commun., 2011, 41 (5), 762–769. Show less

  • Department of Chemistry, Deogiri College
    • Aurangabad, Mahrashtra, India
    • Project Trainee
      • Aug 2009 - Aug 2010

      Research Training at Department of Chemistry, Deogiri College, Aurangabad, India. During this period, I have worked on “Synthesis of β-enamino ketone using sulfated tin oxide (STO) development of novel synthetic methods using nanoparticles as a catalyst”, under the supervision of Prof. Dr. Rajendra P. Pawar. Achievement in Project Trainee: 1.“An expeditious synthesis of bioactive 4-Aryl-3,4-dihydropyrimidines using in situ generated HCl” Sunita B. Shinde, Ambadas B. Rode, Satish A. Dake, Dattatry S. Bhosale, Vinayak S. Sonekar and Rajendra P. Pawar, Int. J. Ind. Chem., 2010, 1 (1), 46–71. Show less

    • Research Services
    • 700 & Above Employee
    • Project Trainee
      • Feb 2009 - Aug 2009

      Research guest work at National Chemical Laboratory, Division of Organic Chemistry, Pune, India. During this period, I have worked on “Synthesis of biologically active molecules”, under the supervision of Dr. Subhash P. Chavan (Sci-G). Research guest work at National Chemical Laboratory, Division of Organic Chemistry, Pune, India. During this period, I have worked on “Synthesis of biologically active molecules”, under the supervision of Dr. Subhash P. Chavan (Sci-G).

Education

  • University of Pardubice
    Ph.D., Organic Chemistry
    2011 - 2017
  • Maharashtra Udaygiri Mahavdiyalaya, Udgir
    M.Sc. (Organic Chemistry), Firtst Class
    2006 - 2008
  • Maharashtra Udaygiri Mahavdiyalaya, Udgir
    B.Sc., Chemistry, Botany, Zoology
    2003 - 2006

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