Douglas Lopez

Senior Systems Engineer at Roche Sequencing USA
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Contact Information
us****@****om
(386) 825-5501
Location
Fremont, California, United States, US
Languages
  • English -
  • Spanish -

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Experience

    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Senior Systems Engineer
      • Mar 2022 - Present

    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Systems Integration Engineer
      • Oct 2021 - Mar 2022

    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Hardware Development Engineer
      • Mar 2020 - Oct 2021

      Owner for the design, development, and verification of multiple subsystems of a proof of concept DNA sequencer Subsystems: Real-time microsecond resolution EtherCAT PLC to control multi-axis gantry Multichannel liquid handling system Automated environmental containment enclosure Consolidated device script-based execution control and graphical user interface Created online sequencing data management database and user interface, enabling cross site collaboration for more… Show more Owner for the design, development, and verification of multiple subsystems of a proof of concept DNA sequencer Subsystems: Real-time microsecond resolution EtherCAT PLC to control multi-axis gantry Multichannel liquid handling system Automated environmental containment enclosure Consolidated device script-based execution control and graphical user interface Created online sequencing data management database and user interface, enabling cross site collaboration for more than 30 users across 3 sites in the US and China, a cost saving of at least $100k Integrated biochemisty user feedback for data management system, adding requested user features such as automated reports, while allowing traceability for each sequencing run back to manufacturing data Built and delivered an automated imaging QC tool for Chinese manufacturing team to increase process turnaround time, reduce human errors, and increase process efficiency by more than 10 fold Lead design validation testing and data analysis for sequencer instrument subsystem; demonstrated reliability and provided design improvement and peak operation condition feedback Developed python software tools for automated analysis of device execution log as an evaluation matrix for instrument development, verification and validation activities Extended the validation capability of python based fluidic characterization method for future generation sensor development, speeds up data processing time from several weeks to several days with improved accuracy

    • Hardware Engineer II
      • Aug 2019 - Mar 2020

      Designed and constructed automated testing fixtures for design verification of sequencer fluidic consumables Created python software data analysis tools for video analysis of fluidic efficiency within sequencer flow cells during execution Assembly and testing of DNBLab E Gen 0 and Gen 1 sequencer subsystems for hardware verification Collaborated with biochemistry team to develop SOP and work-flow scripts for use with Gen 0 and Gen 1 sequencer Developed python… Show more Designed and constructed automated testing fixtures for design verification of sequencer fluidic consumables Created python software data analysis tools for video analysis of fluidic efficiency within sequencer flow cells during execution Assembly and testing of DNBLab E Gen 0 and Gen 1 sequencer subsystems for hardware verification Collaborated with biochemistry team to develop SOP and work-flow scripts for use with Gen 0 and Gen 1 sequencer Developed python software tools to automate data analysis of OQC testing images; transfered tools to manufacturing to allow them to easily monitor batch quality Python analysis of large QC datasets to track system critical parameters and set QC test specifications

    • Hardware Engineering Intern
      • Apr 2018 - Aug 2019

      Construct and calibrate microfluidic device testing methods to allow modular testing of designs Develop Python software for automated test data analysis including: signal processing, image analysis, manipulation of large datasets, statistical analysis of multiple variables, professional graphical display of results Develop and conduct verification and validation studies for product concept hardware Collaboratively conduct microfluidics testing, from design of experiment to… Show more Construct and calibrate microfluidic device testing methods to allow modular testing of designs Develop Python software for automated test data analysis including: signal processing, image analysis, manipulation of large datasets, statistical analysis of multiple variables, professional graphical display of results Develop and conduct verification and validation studies for product concept hardware Collaboratively conduct microfluidics testing, from design of experiment to data analysis Conduct and record microfluidics experiments using prototype hardware Construct, troubleshoot, investigate, and modify prototype hardware for testing Compose easy-to-read reports and presentations for stakeholders of various influence Document hardware adjustments, standard operating procedures, and technical reports Diligently document experimental observations and insights

    • United States
    • Higher Education
    • 700 & Above Employee
    • Lecturer
      • Jan 2019 - Jul 2019

      Classes: Experimental Methods in Biomedical Engineering Organize and manage laboratory activities for graduate students Lab topics include: tensile testing, contact angle measurements, cell culture, motion tracking and gait analysis, gauge R&R

    • Graduate Teaching Assistant
      • Aug 2016 - Dec 2018

      Classes: Biomedical Engineering Fundamentals, Physiology for Engineers, Biomaterials, Introduction to Biomedical Engineering Design (Python) Guide students through lab work ensuring safety, correctness, and organization Collaborate with other lab instructors to adjust or create lab activities Prepare all aspects for a weekly lab: ordering equipment, preparing solutions, testing procedures, and assisting other lab instructors with difficulties Lab topics include:… Show more Classes: Biomedical Engineering Fundamentals, Physiology for Engineers, Biomaterials, Introduction to Biomedical Engineering Design (Python) Guide students through lab work ensuring safety, correctness, and organization Collaborate with other lab instructors to adjust or create lab activities Prepare all aspects for a weekly lab: ordering equipment, preparing solutions, testing procedures, and assisting other lab instructors with difficulties Lab topics include: spectroscopy, bioinformatics, ELISA, pulmonary function, ECG monitoring, survival analysis, and statistical analysis of experimental data

  • Self Employed
    • Fresno, California Area
    • Personal Tutor
      • Jun 2013 - Aug 2015

      · Instructed students on material in which they are having difficulty · Helped students learn study skills and apply them to their current studies · Assisted students with their homework assignments · Monitored groups of up to 5 and help them with any subject grades 9-12 · Instructed students on material in which they are having difficulty · Helped students learn study skills and apply them to their current studies · Assisted students with their homework assignments · Monitored groups of up to 5 and help them with any subject grades 9-12

    • Substitute Teacher
      • Sep 2013 - Jun 2015

      · Developed positive working relationships with teaching staff members and administrators · Followed detailed lesson plans · Led classroom of 30+ students through lessons, assessments, independent work · Incorporated programs (Microsoft Word, PowerPoint, Excel, and Prezi) into teaching methods · Demonstrated use of Cloud based storage such as Dropbox and Google Drive to students and teachers · Attended trainings on in class usage of document cameras, Smartboards, and relevant… Show more · Developed positive working relationships with teaching staff members and administrators · Followed detailed lesson plans · Led classroom of 30+ students through lessons, assessments, independent work · Incorporated programs (Microsoft Word, PowerPoint, Excel, and Prezi) into teaching methods · Demonstrated use of Cloud based storage such as Dropbox and Google Drive to students and teachers · Attended trainings on in class usage of document cameras, Smartboards, and relevant software · Monitored attendance using Powerschool software

    • Varsity Water Polo Assistant Coach
      • Jul 2013 - Jun 2015

      · Planned a variety of practice drills and workouts to enhance physical strength and skills of players · Supervised 20 - 30 student-athletes during daily practices and enforced disciplinary consequences · Mentored individual players by advising techniques to improve decision-making in high stress situations

    • Long Term Middle School Substitute Teacher
      • Dec 2014 - Feb 2015

      · Contributed to Professional Learning Community (PLC) in planning curriculum and teaching methods · Collaborated with other teachers to produce education aids · Planned daily lessons for 6th grade math, science, and narrative writing · Monitored students during testing

    • Long Term High School Substitute Teacher
      • Oct 2013 - Dec 2013

      · Planned daily lessons for multiple classes of High School science including: AP Chemistry, Chemistry, and Conceptual Physics, AP European History, World History · Developed and administered assessments and vigilantly monitor testing for unethical behavior · Graded student work in a timely manner and managed grade book in detail · Developed teacher-student relationships in order to mediate disputes between students, help students with personal problems, motivate students of varying… Show more · Planned daily lessons for multiple classes of High School science including: AP Chemistry, Chemistry, and Conceptual Physics, AP European History, World History · Developed and administered assessments and vigilantly monitor testing for unethical behavior · Graded student work in a timely manner and managed grade book in detail · Developed teacher-student relationships in order to mediate disputes between students, help students with personal problems, motivate students of varying academic skill and diverse backgrounds to assume personal responsibility · Planned and wrote lessons plans for other substitute teachers · Consistently attended weekly meetings with Peer Learning Community (PLC)

    • IT Consultant
      • Jun 2014 - Dec 2014

      · Maintained and supported user hardware through troubleshooting · Provided technical support and installation of user hardware · Consulted on hardware choice and Bluebeam Revu software usage instruction · Maintained and supported user hardware through troubleshooting · Provided technical support and installation of user hardware · Consulted on hardware choice and Bluebeam Revu software usage instruction

Education

  • San Jose State University
    Master of Science (MS), Biomedical Engineering
    2015 - 2018
  • University of California, Santa Barbara
    Bachelor of Arts (BA), Psychology
    2009 - 2013

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