Douglas Faget
Scientist II at Pheast Therapeutics- Claim this Profile
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English Native or bilingual proficiency
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Portuguese Native or bilingual proficiency
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Spanish Elementary proficiency
Topline Score
Bio
Credentials
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Design and Interpretation of Clinical Trials
Coursera Course CertificatesMay, 2016- Nov, 2024
Experience
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Pheast Therapeutics
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United States
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Biotechnology
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1 - 100 Employee
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Scientist II
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Jul 2023 - Present
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Washington University in St. Louis
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United States
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Higher Education
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700 & Above Employee
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Postdoc Research Associate
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Apr 2018 - Jul 2023
My focus while at this position was to better understand the impact of stress-induced pathways in the tumor microenvironment on tumor immunity and leverage this knowledge to boost immunotherapy response in metastatic breast cancer. Duties: - Designed and conducted experiments to support the development of ongoing projects. - Provided experimental solutions to address specific demands independently or in collaboration with other team members. - Stay up-to-date with relevant scientific literature pertaining to ongoing projects. - Fostered partnerships with external researchers to advance project goals. - Trained and mentored colleagues/graduate students to build their technical skills and expertise. - Delivered seminars on recent developments in the fields of cancer immunology, senescence and tumor microenvironment. Show less
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Instituto Nacional de Câncer
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Hospitals and Health Care
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700 & Above Employee
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Postdoctoral Researcher
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Nov 2015 - Mar 2018
My focus while at this position was to investigate the mechanisms by which the transcription factor NFAT1 drives apoptotic cell death in tumor cells and how to leverage this knowledge to develop an adenoviral-based antitumor therapy.- Designed and executed experiments to support the development of several research projects.- Trained other coworkers.- Delivered seminars about recent and relevant papers in oncology and immunology.- Co-authored two original research articles.- Organized and oversaw “INCA’s Scientific Initiation and Graduation Week”, including evaluating student presentations. Show less
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PhD Candidate
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Mar 2011 - Oct 2015
- Planned and executed experiments to support the development of my thesis project about NFAT1-based gene therapy in cancer and the role of N- and C- terminal domains in NFAT-driven apoptosis.- Trained other colleagues.- Delivered seminars about recent and relevant papers in oncology and immunology.- Successfully published a first-author paper and co-authored another one.- Authored a book chapter detailing experimental protocols to analyze cell cycle and death by flow cytometry.- Established a laboratory protocol to produce recombinant adenovirus. Show less
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Instituto Nacional de Câncer
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Hospitals and Health Care
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700 & Above Employee
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Master's Student
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Mar 2008 - Mar 2010
- Planned and executed experiments to support the development of my dissertation project regarding the regulation of cell death by different NFAT1 isoforms. - Presented seminars about recent and relevant papers in oncology. - Contributed to a paper published in 2012 with data obtained while at this position. - Taught a practical course on “Experimental assays for gene expression studies” for undergraduate students during the I Summer Course in Experimental Oncology at INCA. - Planned and executed experiments to support the development of my dissertation project regarding the regulation of cell death by different NFAT1 isoforms. - Presented seminars about recent and relevant papers in oncology. - Contributed to a paper published in 2012 with data obtained while at this position. - Taught a practical course on “Experimental assays for gene expression studies” for undergraduate students during the I Summer Course in Experimental Oncology at INCA.
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Education
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Brazilian National Cancer Institute (INCA)
PhD in Oncology, Cellular and Molecular Biology -
Brazilian National Cancer Institute (INCA)
MSc in Oncology, Cellular and Molecular Biology -
UFRJ - Universidade Federal do Rio de Janeiro
Bachelor's degree in Medical Biology -
Invitare Pesquisa Clínica (Clinical Research)
Professional Training in Clinical Research