Experience

Cytovance Biologics

• United States
• Biotechnology Research
• 100 - 200 Employee

• Associate Director of Microbial Bioprocess

  • Oct 2021 - Present

  Oklahoma City, Oklahoma, United States



Cov5 BioTech Consulting, LLC

• BioProcess & Manufacturing Consultant

  • Jul 2012 - Oct 2021

  -Collaboration and consultation with former colleagues, clients and biotech professionals. -A concise and transparent knowledge base from over 25 years experience working in different biotech areas. -Advise on R&D, process development, PAT, DoE, and tech transfer. -GMP manufacturing and validation assistance.

• Microbial Manufacturing Manager

  • Aug 2018 - Oct 2018

  Oklahoma City, Oklahoma Area Contract Position -Start up advice for fermentation processes for potential and current clients at 1000L scale. - Process equipment readiness through CIP/COP and SIP implementation. - Validation (IQ/OQ/PQ) review and assistance. - Prepare and organize SOPs and batch records.

• Sr. PD Scientist

  • Feb 2015 - Nov 2015

  Oklahoma City, Oklahoma Area Contract Position -Fermentation processes required by potential and current clients. -Process characterization (DOE) readiness and implementation studies for process development engineering and cGMP manufacturing scale up. -Select DSP (centrifugation and filtration techniques including refolding, depth filtration and TFF) -Protein purification experience -Operation of specific and critical downstream and analytical equipment - Validation (IQ/OQ/PQ) protocol writing and… Show more Contract Position -Fermentation processes required by potential and current clients. -Process characterization (DOE) readiness and implementation studies for process development engineering and cGMP manufacturing scale up. -Select DSP (centrifugation and filtration techniques including refolding, depth filtration and TFF) -Protein purification experience -Operation of specific and critical downstream and analytical equipment - Validation (IQ/OQ/PQ) protocol writing and implementation. Root cause analysis and CAPA when needed. -Responsible for presenting the status of specific projects to senior management. -Training and coaching of technical personnel. Show less

• Fermentation Manager, Manufacturing

  • Jun 2011 - Jul 2012

  Oklahoma City, Oklahoma Area Contract Manufacturing Organization - E.coli and Yeast fermentations under CGMP compliance. - IQ/OQ/PQ validation -Responsible for presenting the status of current projects to senior management team. -Key contact for technology transfer between PD, clients and manufacturing. -Supervision of operators and other technical personnel.



Merial

• Germany
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Fermentation Scientist

  • Jan 2009 - May 2011

  Athens, GA Animal Vaccines: -Batch and fed batch fermentations of current and potential bacterins and DNA therapeutics -Implement optimization and scale up/scale down studies under DOE specifications from shake flask to 400L scale size -Point person for technology transfer between R&D and Industrial Operations in NA and EU. -Supervise research biologists and technicians.



Bioexpression and Fermentation Facility, University of Georgia

• Fermentation Scientist

  • Mar 2007 - Dec 2008

  Athens, Georgia Area Contract Manufacturing (recombinant protein and biofuel technology) -Conducted batch, fed batch and continuous fermentations for various anaerobic and aerobic processes (Clostridium, E. coli, & Saccharomyces)requested by academic and industrial customers from 1L to 1000L scale size. -Lead liaison for specific projects. Mentored technical personnel.



ZymoGenetics, Inc

• Scientist, BioProcess Development

  • Apr 1998 - Dec 2006

  Seattle, WA Human Therapeutic Proteins -Transferred fermentation technology, cell disruption and recovery at 5L to 2500L under GLP and cGMP standards, using recombinant Saccharomyces, Pichia, and E. coli expression systems. -Optimization & feasibility perfusion cell culture (CHO) from 3L to 130L scale. -Negotiated technology transfer with contract manufacturers and liaison for internal project teams. -Supervised research associates and interns.



Agrium, Inc.

• United States
• Chemical Manufacturing

• BioManufacturing Coordinator

  • Mar 1994 - Apr 1998

  Saskatoon, SK, Canada BioFertilizers -Determine fermentation parameters for scale-up to pilot plant and commercial production levels. -Manufactured bacterial (e.g. Pseudomonas, Serratia, and Rhizobium) and fungal (e.g. Coniothirum) inoculants for internal and external customers.



Imperial Oil Ltd.

• Oil and Gas
• 1 - 100 Employee

• Research Technologist

  • Jun 1990 - Feb 1994

  Saskatoon, SK, Canada Microbial Inoculants -Researched growth curves and scale-up procedures of soil bacteria and fungi. -Conducted survival studies and bio-assay to compare formulation and product packaging options.