Doug Rains
Chief Scientific Officer at Quantigen Genomic Services- Claim this Profile
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Bio
Experience
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Quantigen Biosciences
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United States
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Research Services
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1 - 100 Employee
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Chief Scientific Officer
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Jun 2015 - Present
Quantigen works closely with both non-profit (e.g., BMGF, University of Washington) and industry partners to develop, validate, and deploy laboratory tests. For example, we constructed a high-throughput, molecular-based tool for performing population-wide surveillance of soil-transmitted helminth infections in low- and middle-income countries — one actively being used at Quantigen and elsewhere to gauge the efficacy of a novel treatment protocol. More recently, Quantigen co-developed (with Corteva, LGC, and BMGF) a low-cost, minimally invasive SARS-CoV2 test and UHT platform configuration that can process 100K tests per day. We also work with university and industry clients to develop basic- and translational-research solutions, including those based on qPCR/dPCR, capillary and next-gen sequencing, and immunoassays. As a CLIA/CAP, 50 state-licensed, ISO 15189 clinical diagnostic lab, we offer select in-house testing and validation support for pharmacogenetics, both to large U.S. and international clients. Finally, Quantigen maintains expertise in medical device development, as well as the attendant development tracking (ISO 13485) and regulatory filing requirements for either FDA 510K or IVD-R approvals. Show less
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Merit Laboratory Partners
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Hospitals and Health Care
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1 - 100 Employee
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Genetic Testing Program Director, Merit Laboratory Partners
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Aug 2013 - Jun 2015
Directed Merit’s program for genetic testing, where I oversaw all phases of test design, validation and implementation of pharmacogenetic testing. Directed Merit’s program for genetic testing, where I oversaw all phases of test design, validation and implementation of pharmacogenetic testing.
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Life Technologies
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United States
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Biotechnology Research
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700 & Above Employee
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Field Applications Specialist
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May 2003 - Jun 2013
Trained and supported customers in qPCR experimental design, hardware and software use, data analysis, and much more. Also wrote and presented the Ask TaqMan video series, a freely available educational tool that has been used to torture hundreds of poor technicians and graduate students over the years. Trained and supported customers in qPCR experimental design, hardware and software use, data analysis, and much more. Also wrote and presented the Ask TaqMan video series, a freely available educational tool that has been used to torture hundreds of poor technicians and graduate students over the years.
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Texas State University
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United States
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Higher Education
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700 & Above Employee
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Senior Laboratory Technician
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Aug 1997 - Apr 2003
Our lab conducted tumorigenesis studies in a Xiphophorus-based model for melanoma. As we worked with pure-bred strains of different species that could be both cross-bred and back-crossed, we were able to apply techniques drawn from both traditional Mendelian as well as molecular genetics in our studies. Our lab conducted tumorigenesis studies in a Xiphophorus-based model for melanoma. As we worked with pure-bred strains of different species that could be both cross-bred and back-crossed, we were able to apply techniques drawn from both traditional Mendelian as well as molecular genetics in our studies.
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UT Health San Antonio
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United States
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Higher Education
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700 & Above Employee
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Senior Laboratory Technician
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Jan 1995 - Aug 1997
Conducted studies on the role of microsatellite instability in the tumorigenesis of breast and brain cancers. Conducted studies on the role of microsatellite instability in the tumorigenesis of breast and brain cancers.
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Washington University School of Medicine in St. Louis
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Hospitals and Health Care
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700 & Above Employee
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Laboratory Technician
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Aug 1989 - Jul 1993
Worked primarily on the Human Genome Project in the lab of Helen Donis-Keller. As these were pre-automated sequencing days, our lab created early physical and genetic maps using methods such as cosmid and YAC library screening and Southern blotting. Worked primarily on the Human Genome Project in the lab of Helen Donis-Keller. As these were pre-automated sequencing days, our lab created early physical and genetic maps using methods such as cosmid and YAC library screening and Southern blotting.
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Education
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University of South Carolina-Columbia
Master of Arts (M.A.), English Literature -
Washington University in St. Louis
Bachelor of Arts (B.A.), Biology, English