Doris Fu
Associate Scientist at Cellarity- Claim this Profile
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Chinese Native or bilingual proficiency
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English Native or bilingual proficiency
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Bio
Experience
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Cellarity
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United States
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Biotechnology Research
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100 - 200 Employee
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Associate Scientist
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Jul 2022 - Present
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Massachusetts Institute of Technology
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United States
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Higher Education
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700 & Above Employee
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Research Assistant
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Jan 2021 - Jul 2022
Study immunotherapy failure in metastatic melanoma patients through bulk and single cell RNA-seq, ATAC-seq, and WES data Use RNA velocity and pseudo-time trajectory inference to elucidate immune cell states under different therapies Uncover lymphoid-myeloid crosstalk induced by immunotherapies Develop novel deep learning framework for scRNA-scATAC integration and benchmark existing methods Use meta-learning approaches to leverage pan-cancer data in predicting immunotherapy response Show less
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Broad Institute of MIT and Harvard
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Research Services
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700 & Above Employee
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Student Researcher, Regev Lab, Wu Lab
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Jan 2019 - Feb 2021
Responsible for RNA and RPF sequence analysis, transcriptional efficiency, stop codon read-through, and alternative reading frames studies in chronic lymphocytic leukemia Next-generation sequencing of mRNA and explore peptides’ contribution to MHC I presentation Generate pipelines to analyze peptides and compare against annotated peptides and generate figures for a manuscript currently in preparation Responsible for RNA and RPF sequence analysis, transcriptional efficiency, stop codon read-through, and alternative reading frames studies in chronic lymphocytic leukemia Next-generation sequencing of mRNA and explore peptides’ contribution to MHC I presentation Generate pipelines to analyze peptides and compare against annotated peptides and generate figures for a manuscript currently in preparation
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Accenture
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Ireland
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Business Consulting and Services
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700 & Above Employee
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Consulting Development Analyst
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Jun 2020 - Aug 2020
Used agile methods and JIRA to assist project management for an international team of 15 Refined project scope, analyzed project progress, identified key challenges and mitigation, proposed end-of-year projection Presented 2 major deliverables to team leaders Used agile methods and JIRA to assist project management for an international team of 15 Refined project scope, analyzed project progress, identified key challenges and mitigation, proposed end-of-year projection Presented 2 major deliverables to team leaders
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Microsoft New England Research and Development Center
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United States
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1 - 100 Employee
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Researcher
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Jan 2020 - Jan 2020
Developed a novel non-parametric algorithm for single-cell sequencing post-clustering differential expression analysis Developed a novel non-parametric algorithm for single-cell sequencing post-clustering differential expression analysis
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Regeneron
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United States
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Biotechnology
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700 & Above Employee
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Molecular Profiling Intern
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Jun 2019 - Aug 2019
Created a patentable machine learning model to translate mouse gene expression to analogous human conditions Developed a package to transform and filter microarray data for internal usage Teamed with University Relations to connect students in greater Boston area to the corporate Created a patentable machine learning model to translate mouse gene expression to analogous human conditions Developed a package to transform and filter microarray data for internal usage Teamed with University Relations to connect students in greater Boston area to the corporate
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Morgan Stanley
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United States
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Financial Services
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700 & Above Employee
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Wealth Management Intern
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Jun 2018 - Aug 2018
Tracked U.S. and China companies in healthcare, technology, and finance sectors and leveraged firm’s extensive research to analyze investment opportunities Assisted financial advisors to calibrate and execute multi-million bearing equity models and generated comprehensive management strategy reports Demonstrated marketing initiatives through attending corporate seminars and sponsored events hosting high net worth clients Received clients and answered incoming calls Tracked U.S. and China companies in healthcare, technology, and finance sectors and leveraged firm’s extensive research to analyze investment opportunities Assisted financial advisors to calibrate and execute multi-million bearing equity models and generated comprehensive management strategy reports Demonstrated marketing initiatives through attending corporate seminars and sponsored events hosting high net worth clients Received clients and answered incoming calls
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iResearch Institute
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Greater New York City Area
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Junior Instructor
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Jul 2017 - Aug 2017
Taught solution chemistry and laboratory fundamentals to a class of 18 high school students and supervised student practice Prepared students for local and national science fairs by advising students on project direction, experiment revision, scientific communication, and presentation skills Taught solution chemistry and laboratory fundamentals to a class of 18 high school students and supervised student practice Prepared students for local and national science fairs by advising students on project direction, experiment revision, scientific communication, and presentation skills
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The Mount Sinai Hospital
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Greater New York City Area
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Nephrology Research Intern
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Jun 2016 - Aug 2016
• Discovered a compound’s ability in inhibiting fibrogenesis and investigated its mechanism • Selected drug candidate through screening process, validated its activity, confirmed its interaction with the drug target, and evaluated its toxicity • Produced individual project: Potent treatment of renal fibrosis: A novel inhibitor of HIPK2 - Smad3 interaction • Discovered a compound’s ability in inhibiting fibrogenesis and investigated its mechanism • Selected drug candidate through screening process, validated its activity, confirmed its interaction with the drug target, and evaluated its toxicity • Produced individual project: Potent treatment of renal fibrosis: A novel inhibitor of HIPK2 - Smad3 interaction
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Education
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Massachusetts Institute of Technology
Master of Engineering - MEng, Computer Science and Molecular Biology -
Massachusetts Institute of Technology
Bachelor of Science - BS, Computer Science and Molecular Biology