Dixcy Jaba Sheeba J M
Postdoctoral Associate at UPMC Hillman Cancer Center- Claim this Profile
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Bio
Experience
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UPMC Hillman Cancer Center
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United States
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Hospitals and Health Care
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400 - 500 Employee
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Postdoctoral Associate
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Oct 2021 - Present
• Generated syngeneic mouse models of invasive lobular breast carcinoma and lymph node metastasis. • Generated gene knockout cell lines using CRISPR-Cas technology. • Performed high throughput RNA-Seq analysis to identify differentially expressed genes in Lung Mets from mammary fat pad tumors and axillary lymph node tumors • Generated syngeneic mouse models of invasive lobular breast carcinoma and lymph node metastasis. • Generated gene knockout cell lines using CRISPR-Cas technology. • Performed high throughput RNA-Seq analysis to identify differentially expressed genes in Lung Mets from mammary fat pad tumors and axillary lymph node tumors
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Centre of Human Genetics
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Bengaluru, Karnataka, India
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Project Associate
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Jun 2021 - Sep 2021
• Profiled the gene signature of castrate-resistant (CaR) and castrate-sensitive clinical samples of prostate cancer patients. • Assessed the prognostic potential of CaR-specific genes using the Kaplan-Meier Plots • Using R software, evaluated the correlation of CaR genes with biochemical recurrence, Gleason score, and tumorigenesis using TCGA data • Profiled the gene signature of castrate-resistant (CaR) and castrate-sensitive clinical samples of prostate cancer patients. • Assessed the prognostic potential of CaR-specific genes using the Kaplan-Meier Plots • Using R software, evaluated the correlation of CaR genes with biochemical recurrence, Gleason score, and tumorigenesis using TCGA data
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Education
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Indian Institute of Technology, Guwahati
Doctor of Philosophy - PhD, Biological/Biosystems Engineering -
Indian Institute of Technology, Guwahati
M.Tech, Biotechnology -
Government College of Technology, Coimbatore
B.Tech, Biotechnology