Dixcy Jaba Sheeba J M

Postdoctoral Associate at UPMC Hillman Cancer Center
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Contact Information
us****@****om
(386) 825-5501
Location
Pittsburgh, Pennsylvania, United States, US

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Experience

    • United States
    • Hospitals and Health Care
    • 400 - 500 Employee
    • Postdoctoral Associate
      • Oct 2021 - Present

      • Generated syngeneic mouse models of invasive lobular breast carcinoma and lymph node metastasis. • Generated gene knockout cell lines using CRISPR-Cas technology. • Performed high throughput RNA-Seq analysis to identify differentially expressed genes in Lung Mets from mammary fat pad tumors and axillary lymph node tumors • Generated syngeneic mouse models of invasive lobular breast carcinoma and lymph node metastasis. • Generated gene knockout cell lines using CRISPR-Cas technology. • Performed high throughput RNA-Seq analysis to identify differentially expressed genes in Lung Mets from mammary fat pad tumors and axillary lymph node tumors

  • Centre of Human Genetics
    • Bengaluru, Karnataka, India
    • Project Associate
      • Jun 2021 - Sep 2021

      • Profiled the gene signature of castrate-resistant (CaR) and castrate-sensitive clinical samples of prostate cancer patients. • Assessed the prognostic potential of CaR-specific genes using the Kaplan-Meier Plots • Using R software, evaluated the correlation of CaR genes with biochemical recurrence, Gleason score, and tumorigenesis using TCGA data • Profiled the gene signature of castrate-resistant (CaR) and castrate-sensitive clinical samples of prostate cancer patients. • Assessed the prognostic potential of CaR-specific genes using the Kaplan-Meier Plots • Using R software, evaluated the correlation of CaR genes with biochemical recurrence, Gleason score, and tumorigenesis using TCGA data

Education

  • Indian Institute of Technology, Guwahati
    Doctor of Philosophy - PhD, Biological/Biosystems Engineering
    2014 - 2021
  • Indian Institute of Technology, Guwahati
    M.Tech, Biotechnology
    2012 - 2014
  • Government College of Technology, Coimbatore
    B.Tech, Biotechnology
    2008 - 2012

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