Diane Nakamura
Postdoctoral Researcher at McGill University- Claim this Profile
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English Native or bilingual proficiency
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French Limited working proficiency
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Credentials
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Safe Use of Biological Safety Cabinets
McGill UniversitySep, 2018- Sep, 2024 -
Workplace Hazardous Materials Information System (W.H.M.I.S.) for Lab Researchers
McGill UniversitySep, 2018- Sep, 2024 -
Advanced Certification for Animal Handling and Surgery
Canadian Council on Animal Care
Experience
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McGill University
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Canada
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Higher Education
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700 & Above Employee
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Postdoctoral Researcher
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Jan 2020 - Present
Industrial postdoctoral researcher funded by Revalesio Corporation. Laboratory: Genetic defects associated with mitochondrial deficiencies. Dr. Eric Shoubridge, http://molecular-neurogenetics.mcgill.ca Project: Evaluation of the potential efficacy of charge-stabilized nanostructure saline (RNS60) for primary mitochondrial diseases. Analysis of metabolomics, transcriptomics, and mitochondrial function in immortalized cell lines derived from patients with rare mitochondrial… Industrial postdoctoral researcher funded by Revalesio Corporation. Laboratory: Genetic defects associated with mitochondrial deficiencies. Dr. Eric Shoubridge, http://molecular-neurogenetics.mcgill.ca Project: Evaluation of the potential efficacy of charge-stabilized nanostructure saline (RNS60) for primary mitochondrial diseases. Analysis of metabolomics, transcriptomics, and mitochondrial function in immortalized cell lines derived from patients with rare mitochondrial diseases, such as Leigh syndrome and ALS/FTD.Publications: Rao VTS, Khan D, Jones RG, Nakamura DS, Kennedy TE… Antel JP. (2016). Potential Benefit of the Charge-Stabilized Nanostructure Saline RNS60 for Myelin Maintenance and Repair. Scientific Reports, 6, 30020. http://doi.org/10.1038/srep30020 Show more Show less
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Doctoral Student
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Sep 2013 - Sep 2019
Laboratory: Neurodegenerative Disease and Cell Biology. Dr. Timothy Kennedy, https://www.kennedylabmcgill.comProject: Investigating the role of small proteins on CNS myelin maintenance and stability. Application of a advanced super-resolution imaging techniques and biochemistry to identify the signalling pathways that promote mitochondrial function and myelin health in the context of neurodegenerative diseases like Multiple Sclerosis. Publications:Nakamura DS, Lin YH… Laboratory: Neurodegenerative Disease and Cell Biology. Dr. Timothy Kennedy, https://www.kennedylabmcgill.comProject: Investigating the role of small proteins on CNS myelin maintenance and stability. Application of a advanced super-resolution imaging techniques and biochemistry to identify the signalling pathways that promote mitochondrial function and myelin health in the context of neurodegenerative diseases like Multiple Sclerosis. Publications:Nakamura DS, Lin YH, Khan D, Gothié JM, de Faria O Jr, Dixon JA, McBride HM, Antel JP, Kennedy TE. Mitochondrial dynamics and bioenergetics regulated by netrin-1 in oligodendrocytes. Glia. 2020 Sep 10. doi: 10.1002/glia.23905. Epub ahead of print. PMID: 32910475.Landry MJ, Gu K, Harris SN, Al-Alwan L, Gutsin L, De Biasio D, Jiang B, Nakamura DS, Corkery TC, Kennedy TE, Barrett CJ. Tunable Engineered Extracellular Matrix Materials: Polyelectrolyte Multilayers Promote Improved Neural Cell Growth and Survival. Macromol Biosci. 2019 May;19(5):e1900036. doi: 10.1002/mabi.201900036. Epub 2019 Apr 2. PMID: 30938926. Show more Show less
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Queen's University
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Canada
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Higher Education
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Master of Science
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May 2011 - May 2013
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Teaching Assistant (Anatomy)
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Sep 2011 - Dec 2011
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Undergraduate Research Student
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Sep 2010 - May 2011
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Health Canada
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Canada
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Government Administration
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700 & Above Employee
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Research Assistant
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May 2009 - Aug 2010
Laboratory: Pharmacology and Toxicology (Dr. Raymond Poon)Toxicological screening of potential biodiesel feedstocks. Using a multidisciplinary approach, performed post-treatment analysis of brain, liver, lung, heart, pancreas, and kidney homogenates to assess cell viability and inflammation.
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Education
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McGill University
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Queen's University
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Queen's University