Dennis Yu Liu
Postdoctoral Researcher at Simon Fraser University - Department of Chemistry- Claim this Profile
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English Native or bilingual proficiency
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Chinese Native or bilingual proficiency
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Credentials
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ORCID
ORCID
Experience
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Simon Fraser University - Department of Chemistry
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Canada
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Higher Education
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1 - 100 Employee
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Postdoctoral Researcher
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Oct 2022 - Present
• Optimized assay quality and throughput for Cell Painting; a high-content imaging assay in osteosarcoma cells using multiplexed fluorescent probes • Automated Cell Painting for high-throughput screening of 40,000 natural product extracts via an integrated platform of liquid handlers, dispensers, incubators, and automated microscopes • Contributed to the development of an in-house image processing and data analysis pipeline using Python and CellProfiler • Designed a high-throughput assay for the functional annotation of bioactive compounds through drug resistance profiling and metabolomics Show less
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McMaster University
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Canada
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Higher Education
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700 & Above Employee
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Research Assistant
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Sep 2014 - Apr 2016
• Heterologous expression and isolation of the small molecule colibactin from commensal gut bacteria; implicated in colorectal cancer • Heterologous expression and isolation of the small molecule colibactin from commensal gut bacteria; implicated in colorectal cancer
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Education
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Simon Fraser University
Doctor of Philosophy - PhD, Chemistry -
McMaster University
Bachelor’s Degree, Biochemistry and Biomedical Research