Experience

Radionetics Oncology

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Scientist 2, Biology

  • Jun 2022 - Present



Sanford Burnham Prebys

• United States
• Research Services
• 500 - 600 Employee

• Postdoctoral Research Associate

  • Dec 2016 - Jun 2022

  a. I have identified a subset of inflammatory astrocytes (ieAstrocytes) in a mouse model of multiple sclerosis (MS) called experimental autoimmune encephalomyelitis (EAE) that are disease relevant as their population size is effected by treatment with an MS disease modifying treatment (DMT) called fingolimod, a sphingosine 1-phosphate (S1P) receptor modulator (eNeuro Sep 2018) b. I have identified a missing link that drives the central nervous system mechanism of action of a drug used to treat multiple sclerosis (MS) through S1P 1 receptor on astrocytes which might be a valuable addition to effective therapeutic treatment (BioRxiv 2022) c. I have identified how S1P modulates glutamate uptake by astrocytes (eNeuro 2021) d. Identified ponesimod-S1P receptor mechanisms in MS (FASEB 2022) Show less



Scripps Research

• United States
• Research Services
• 700 & Above Employee

• Research Associate

  • Apr 2014 - Dec 2016

  Stepped into field of Neurobiology and now expert in a mouse model of multiple sclerosis (EAE), cuprizone induced model of demyelination, astrocyte sphingosine 1 phosphate biology and isolation of spinal cords. Adept in immunohistochemistry, fluorescence microscopy, qPCR, cryosectioning, primary astrocyte cultures, flow cytometry. Stepped into field of Neurobiology and now expert in a mouse model of multiple sclerosis (EAE), cuprizone induced model of demyelination, astrocyte sphingosine 1 phosphate biology and isolation of spinal cords. Adept in immunohistochemistry, fluorescence microscopy, qPCR, cryosectioning, primary astrocyte cultures, flow cytometry.



University of Kentucky

• United States
• Higher Education
• 700 & Above Employee

• • May 2013 - Apr 2014

  Pursued how a bioactive lipid molecule, sphingosine 1-phosphate is stored and released from platelets. This work was published in BBA Molecular and Cell Biology of Lipids, 2014.

• • Aug 2007 - May 2013

  1. Understood platelet biology and importance of platelet secretion heterogeneity. The work not only helped in visualizing the platelet granule morphology but also bolstered the role of platelet exocytosis in life-threatening conditions like stroke and heart attack.This was published in Blood, 20122. Determined a granular pool of bio-active molecule, Sphingosine-1-Phosphate in platelets using platelet secretion deficient mouse models.