Debora Zian
Chemist- Principal Scientist at Axxam S.p.A- Claim this Profile
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Bio
Experience
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Axxam
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Italy
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Biotechnology Research
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100 - 200 Employee
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Chemist- Principal Scientist
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Mar 2020 - Present
Principal Scientist with specific responsibilities in cheminformatic and medicinal chemistry data analysis in the Data Sciences group at Axxam. Support the maintenance and the expansion of Axxam small molecule compound collection and HTS campaigns. Main activities and capabilities: • Evaluation of hit sets in terms of cluster analysis, physicochemical properties and purity. • Selection of new compound subsets for further improvements to the library going forward. • Working with clients to define the joint strategy in hit-to-lead and lead optimization medicinal chemistry. • Assisting in the generation of scientific proposals for integrated drug discovery services. • Working on data analysis, data mining, hit selection and reporting of results for screening campaigns Show less
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ICIQ
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Spain
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Research Services
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100 - 200 Employee
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Postdoctoral Research Scientist
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Jun 2017 - Mar 2020
Postdoctoral Research Scientist at Esteve-ICIQ Joint Unit, working in a collaborative research project between the Spanish pharmaceutical company ESTEVE and ICIQ, dedicated to the development of new chemical processes to obtain new scaffolds and building blocks that can generate new medicinal chemistry libraries with the aim of identifying new lead compounds. Postdoctoral Research Scientist at Esteve-ICIQ Joint Unit, working in a collaborative research project between the Spanish pharmaceutical company ESTEVE and ICIQ, dedicated to the development of new chemical processes to obtain new scaffolds and building blocks that can generate new medicinal chemistry libraries with the aim of identifying new lead compounds.
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Universidad Complutense de Madrid
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Spain
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Higher Education
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700 & Above Employee
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Pre-doctoral Fellowship (F.P.U. program)
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Mar 2013 - May 2017
Pre-doctoral Fellowship (F.P.U. program), working on “The LPA1 and LPA2 receptors as new therapeutic targets for the treatment of nervous system pathologies”, under the supervision of Prof. Dr. María Luz López Rodríguez, Dr. Silvia Ortega Gutiérrez and Dr. Henar Vázquez Villa
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Starting Research Position
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Apr 2012 - Feb 2013
Starting Research Position, working on “Development of compounds for the identification and validation of therapeutic targets using forward and reverse chemistry (SAF2010-22198-C02-01)”, under the supervision of Prof. Dr. María Luz López Rodríguez, Dr. Silvia Ortega Gutiérrez and Dr. Henar Vázquez Villa
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Scripps Research
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United States
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Research Services
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700 & Above Employee
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Pre-doctoral Stay (F.P.U. program)
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Sep 2015 - Dec 2015
Pre-doctoral Stay (F.P.U. program), working on a new method for direct, label-free measurement of ligand binding to native membranes, called Backscattering Interferometry (BSI), under the supervision of Prof. Dr. Jerold Chun and Prof. Dr. Darryl J. Bornhop Pre-doctoral Stay (F.P.U. program), working on a new method for direct, label-free measurement of ligand binding to native membranes, called Backscattering Interferometry (BSI), under the supervision of Prof. Dr. Jerold Chun and Prof. Dr. Darryl J. Bornhop
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ICIQ
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Spain
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Research Services
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100 - 200 Employee
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ICIQ Summer Fellowship
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Jul 2011 - Sep 2011
ICIQ Summer Fellowship, working on “Exploring the reactivity of hypervalent iodine reagents”, under the supervision of Prof. Dr. Kilian Muñiz ICIQ Summer Fellowship, working on “Exploring the reactivity of hypervalent iodine reagents”, under the supervision of Prof. Dr. Kilian Muñiz
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Universidad Complutense de Madrid
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Spain
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Higher Education
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700 & Above Employee
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Erasmus Fellowship 5th year of BSc
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Jan 2011 - Jun 2011
Erasmus Fellowship 5th year of BSc at Medicinal Chemistry Laboratory of Universidad Complutense de Madrid, working on “Development of new ligands for the validation of lysophosphatidic acid receptor LPA1”, under the supervision of Prof. Dr. María Luz López Rodríguez, Dr. Silvia Ortega Gutiérrez and Dr. Henar Vázquez Villa Erasmus Fellowship 5th year of BSc at Medicinal Chemistry Laboratory of Universidad Complutense de Madrid, working on “Development of new ligands for the validation of lysophosphatidic acid receptor LPA1”, under the supervision of Prof. Dr. María Luz López Rodríguez, Dr. Silvia Ortega Gutiérrez and Dr. Henar Vázquez Villa
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Education
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Universidad Complutense de Madrid
PhD Degree in Organic Chemistry, Medicinal Chemistry -
Universidad Complutense de Madrid
MSc in Organic Chemistry -
Università degli Studi di Trieste
BSc in Pharmaceutical Chemistry and Technology (CTF)