David Seftel, MD, MBA
CEO / CFO / CMO at Enable Biosciences- Claim this Profile
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Bio
Experience
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Enable Biosciences
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United States
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Biotechnology Research
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1 - 100 Employee
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CEO / CFO / CMO
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Aug 2015 - 8 years 5 months
South San Francisco, CA Enable Biosciences runs a State and Federal CLIA certified clinical reference laboratory that provides world-leading COVID antibody dried blood spot testing to the California Department of Public Health and others as well as Type 1 diabetes prognostic testing to institutions including Stanford, Mayo, the Joslin Diabetes Center at Harvard, Lund University in Sweden, Israel and nationally in 47 states via an exclusive partnership with the Juvenile Diabetes Research Fund (JDRF), in a world-first… Show more Enable Biosciences runs a State and Federal CLIA certified clinical reference laboratory that provides world-leading COVID antibody dried blood spot testing to the California Department of Public Health and others as well as Type 1 diabetes prognostic testing to institutions including Stanford, Mayo, the Joslin Diabetes Center at Harvard, Lund University in Sweden, Israel and nationally in 47 states via an exclusive partnership with the Juvenile Diabetes Research Fund (JDRF), in a world-first home dried blood spot sample collection program called T1Detect - https://www.jdrf.org/t1d-resources/t1detect/ Enable Biosciences was co-founded with two multi-award-winning Stanford / UC Berkeley PhD candidates and their professor Carolyn Bertozzi at UC Berkeley and currently at Stanford. Enable Biosciences developed, validated and published the performance of its patented, rapid, multiplexable, early disease detection technology in top peer-reviewed medical journals, including the Proceedings of the National Academy of Sciences. The technology called Antibody Detection by Agglutination PCR or ADAP, creates and reads tiny DNA barcodes attached to antibodies of interest in a patients sample. It is 1,000 to 10,000 times more sensitive than any others, while retaining super specificity for unparalleled accuracy. These attributes translate into earlier disease detection making improved patient outcomes possible.
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CEO / CFO / CMO
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Aug 2015 - 8 years 5 months
South San Francisco
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Harvard Business School (HBS) Association of Northern California
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United States
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Education Administration Programs
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1 - 100 Employee
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President of Strategic Initiatives, Harvard Business School Association of Northern California
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Aug 2019 - 4 years 5 months
San Francisco Bay Area In this new role, I serve as the host of a periodic in-depth COVID-19 Webinar series for Harvard Business School Alumni and their guests. 8,000 Harvard Business School Alumni reside in the Bay area. For the post-COVID era, I am spearheading a multifaceted initiative to support Harvard Business School alumni and their companies via the creation of a physical entrepreneurial center in the Bay Area that can also serve as a Club House for the Harvard Business School Association of Northern… Show more In this new role, I serve as the host of a periodic in-depth COVID-19 Webinar series for Harvard Business School Alumni and their guests. 8,000 Harvard Business School Alumni reside in the Bay area. For the post-COVID era, I am spearheading a multifaceted initiative to support Harvard Business School alumni and their companies via the creation of a physical entrepreneurial center in the Bay Area that can also serve as a Club House for the Harvard Business School Association of Northern California, Show less
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The National Institutes of Health
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United States
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Biotechnology Research
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700 & Above Employee
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Research Panel Reviewer
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May 2019 - 4 years 8 months
Washington D.C. Metro Area Appointment as an NIH grant reviewer represents recognition of a sustained and significant contribution to medical science and affords the opportunity to help guide future research towards optimal outcomes for all humanity
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National Institute of Allergy and Infectious Diseases (NIAID)
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United States
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Government Administration
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700 & Above Employee
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Principal Investigator
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Mar 2019 - 4 years 10 months
Principal Investigator and Project Director for improved Lyme disease test development study under the National Institute of Allergy and Infectious Diseases (NIAID) division of the National Institutes of Health.
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Principal Investigator
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Oct 2018 - 5 years 3 months
Principal Investigator of advanced allergy test development for National Institute of Allergy and Infectious Diseases (NIAID) study, focusing on improved food allergy detection.
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Stanford University School of Medicine
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Hospitals and Health Care
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1 - 100 Employee
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Co-Investigator
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Sep 2017 - 6 years 4 months
Stanford Co-Investigator of Juvenile Diabetes Research Fund - Stanford - Enable Biosciences Type 1 Diabetes Assay Performance Study with Prof's Darrell Wilson, M.D., David Maahs, M.D. and Bruce Buckingham, M.D.
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National Science Foundation (NSF)
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United States
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Research Services
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700 & Above Employee
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Principal Investigator and Project Director
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Apr 2016 - 7 years 9 months
Principal Investigator and Project Director for multi-phase National Science Foundation program to develop and deploy an ultra-sensitive, highly specific antibody discovery system to accelerate accurate diagnosis and assist more effective drug development
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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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United States
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Research Services
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200 - 300 Employee
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Principal Investigator and Project Director
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Mar 2016 - 7 years 10 months
South San Francisco Principal Investigator and Project Director for multi-year NIDDK funded project to develop, validate and deploy the world's most sensitive and accurate test for prediction and diagnosis of Type 1 diabetes
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Golden Gate Fields
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United States
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Spectator Sports
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1 - 100 Employee
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Medical Director / Track Physician
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Jan 2000 - 24 years
1100 Eastshore Highway, Berkeley, CA 94710 Manage and serve as part-time clinician in a respected corporate campus urgent care clinic focused on sports medicine and athlete wellness
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Macular Degeneration Foundation, Inc.
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United States
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Non-profit Organizations
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Executive Vice President and Director of Research and Development
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Jun 1995 - Aug 2016
Berkeley Evaluation and funding recommendations for research projects into the cause and cure of macular degeneration, the leading cause of legal blindness in the Western world. Current focus is on funding highly original cutting-edge work in the areas of stem cell and gene therapy. To this end we have funded projects that include seminal stem-cell work at the University of California, Davis as well as served as a major recurring sponsor of the Harvard Age-related Macular Degeneration symposium. I apply… Show more Evaluation and funding recommendations for research projects into the cause and cure of macular degeneration, the leading cause of legal blindness in the Western world. Current focus is on funding highly original cutting-edge work in the areas of stem cell and gene therapy. To this end we have funded projects that include seminal stem-cell work at the University of California, Davis as well as served as a major recurring sponsor of the Harvard Age-related Macular Degeneration symposium. I apply a startup-based philosophy to the identification and funding of promising researchers, promoting a focus on practicality and translational viability, with an emphasis on those projects that propose to achieve viable therapies faster. Show less
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Bay Meadows Racecourse
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United States
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Entertainment Providers
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Medical Director / Track Physician
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Jan 2000 - Sep 2009
2600 S. Delaware, San Mateo, CA 94403 Initiated and ran a corporate campus urgent care clinic that served both as a sports medicine facility and as a employee wellness hub.
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NASA - National Aeronautics and Space Administration
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United States
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Aviation and Aerospace Component Manufacturing
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700 & Above Employee
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Ames Associate - Bioinformatics and Bio Surveillance Technology Development
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Oct 2001 - Oct 2003
Naval Air Station, Moffett Field, Mountain View, CA 94035 Research and program development in the field of advanced bio informatics and bio surveillance, with a special emphasis on assisting NASA technology transfer.
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Vituity Practice Management
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United States
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Hospitals and Health Care
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100 - 200 Employee
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Partner
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Feb 1998 - Sep 2003
222 West 39th Avenue San Mateo, CA 94403 As a Partner in the California Emergency Physicians Medical Group (CEP America) now known as Vituity, served as an Assistant Director of the emergency room at San Mateo County Medical Center, inpatient hospitalist and event management physician. Vituity is the largest provider of emergency medicine physician services in the state of California, and one of the largest providers nationwide, seeing over 5.2 million patients annually.
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San Mateo Medical Center
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United States
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Hospitals and Health Care
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300 - 400 Employee
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Chairperson, Medical Informatics Committee
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Mar 1998 - Sep 2002
222 West 39th Avenue San Mateo, CA 94403 Head of hospital committee evaluating options for improved informatics solutions for both inpatient and outpatient care as well as system-wide linkages to other County facilities.
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Chief Operating Officer
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Feb 1998 - Sep 2002
222 West 39th Avenue San Mateo, CA 94403 Responsible for co-development and deployment of a telemedicine system that linked external clinics and correctional facilities to the emergency room at San Mateo County Medical Center
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Hospitalist Physician
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Feb 1997 - Sep 2001
222 West 39th Avenue San Mateo, CA 94403 Responsible for inpatient medical care of a full range of acuity from intensive care to ward-based medicine, with a special emphasis on pulmonary disease management.
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Attending Physician
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Jun 1995 - Jun 1996
Berwyn, IL Attending physician at a University of Chicago affiliated teaching hospital, responsible for clinical care and teaching of residents and medical students.
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Lancet Hall
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United States
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General Practitioner
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Jan 1986 - Feb 1989
Johannesburg, South Africa. General practitioner serving the full spectrum of primary care patients
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Co-Founder
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Dec 1985 - Jun 1988
Johannesburg, South Africa As a medical student and young doctor, co-founded a traditional African music and dance youth edu-tainment performance company to teach young African mothers to recognize and treat the number one killer of babies in Africa – dehydration due to viral infantile gastroenteritis. Using the idiom of traditional drum and xylophone music, dance and theater, the project was undertaken with the joint support of the University of the Witwatersrand Department of Pediatrics and the Dramatic Arts. Together… Show more As a medical student and young doctor, co-founded a traditional African music and dance youth edu-tainment performance company to teach young African mothers to recognize and treat the number one killer of babies in Africa – dehydration due to viral infantile gastroenteritis. Using the idiom of traditional drum and xylophone music, dance and theater, the project was undertaken with the joint support of the University of the Witwatersrand Department of Pediatrics and the Dramatic Arts. Together with legendary South African Director Janice Honeyman (http://esat.sun.ac.za/index.php/Janice_Honeyman),co-produced the riveting African musical Amabali – It’s Storytime - which was staged at the South Africa's most prestigious performing arts venue - the Market Theatre in 1988. This performance served as an international springboard for the group who then went on to tour Europe and perform in productions in London's prestigious West End. Today the youth leader of the group, Baba Vusi Shibambo teaches the joy of traditional African music to the next generation of children in Arizona and California. Show less
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Education
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Harvard Graduate School of Business Administration, Boston, MA
Masters in Business Administration, Business Administration and Management, General -
Loyola University Medical Center, Loyola Medical School, Maywood, IL
Residency in Internal Medicine, Internal Medicine Specialty Training -
University of California, San Francisco
Entrepreneurship/Entrepreneurial Studies -
Entrepreneurial Management (ETK), Executive Education Program, Harvard Business School, Boston., MA
ETK, Entrepreneurship/Entrepreneurial Studies -
Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, PA
Internship in Internal Medicine, Internal Medicine Specialty Training -
Harvard Medical School and Beth Israel Hospital, Brookline, MA
Transitional Internship in General Surgery, General Surgery Residency Program -
Witwatersrand University, Johannesburg, South Africa
Doctor of Medicine (M.D.), Medicine -
Witwatersrand University, Johannesburg, South Africa
Bachelor of Science (B.Sc.), Biochemistry and Molecular Biology -
University of California, San Francisco