Experience

VC-Backed Biotech NewCo

• United States
• Biotechnology
• 1 - 100 Employee

• Principal Scientist, Immunology

  • May 2022 - Present



Zymeworks Inc.

• Canada
• Biotechnology Research
• 100 - 200 Employee

• Senior Scientist, Exploratory Research Unit for Innovation

  • Jan 2021 - May 2022

• Scientist, Assay Development

  • Jan 2019 - Jan 2021

• Scientist, Immunooncology

  • Jun 2016 - Dec 2018



Harvard Medical School

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Fellow

  • Sep 2013 - Jun 2016

  Supervisor: Dr. Bruce Levy Project 1: Determining the role of neutrophil NETosis in sever asthma ▪ Identified that enucleated neutrophil cytoplasts induce Th17 differentiation and neutrophilia in severe asthma ▪ Utilized a mouse model of asthma and ex vivo immunological assays using primary immune cells Project 2: Determining the role of presqualene diphosphate phosphatase 1 during lung infection ▪ Identified that loss of PDP1 in human and mouse neutrophil leads to reduced NET production ▪ Utilized KO mice, antibody transfection into neutrophils, CRISPR-Cas system Project 3: Development of neutrophil function assays from small volume blood samples ▪ Developed standardized assays using as little as 10,000 cells/test ▪ Led collaborations within Harvard and at MIT ▪ Two co-author publications and two poster presentations at international meetings Activities: Brigham and Women's Hospital Postdoc Leadership Council Member (Communications Committee Co-Chair, 2014 - 2015, and New Initiatives Committee Co-Chair, 2014 - Current) Show less



The Hospital for Sick Children

• Canada
• Hospitals and Health Care
• 700 & Above Employee

• PHD Student

  • Sep 2007 - Aug 2013

  Supervisors: Dr. Nades Palaniyar and Dr. Hartmut Grasemann ▪ Thesis: The Role of Surfactant Protein D in Neutrophil Extracellular Trap (NET)-Mediated Innate Immunity ▪ Published 10 manuscripts in high impact journals (6 first author, 4 co-author) ▪ Used human neutrophils and optimized a medium throughput screening assay and identifid several key signaling pathways involved in NET release ▪ Used a mouse model of lung inflammation and studied the kinetics of neutrophil recruitment and NET release in vivo ▪ Gave numerous oral and poster presentations at local, national and international meetings - received presentation awards Show less



Ottawa Health Research Institute

• MSc Student

  • Sep 2005 - Jun 2007

  Supervisor: Dr. Ruth Slack ▪ Thesis: The role of E2F1 as a downstream target for retinoblastoma (Rb) protein during cortical development. ▪ Identified the differential roles of E2F1 and E2F3 during cortical development in collaboration with another graduate student Supervisor: Dr. Ruth Slack ▪ Thesis: The role of E2F1 as a downstream target for retinoblastoma (Rb) protein during cortical development. ▪ Identified the differential roles of E2F1 and E2F3 during cortical development in collaboration with another graduate student



Samuel Lunenfeld Research Institute

• Research Assistant

  • 2007 - 2007



University of Toronto at Scarborough

• Teaching Assistant

  • Jan 2005 - Jun 2005

  Cell and Molecular Biology. 2nd year. TA duties including assisting and supervising students in laboratory and marking exams. Laboratory exercises include molecular and biochemical techniques such as DNA and protein preparation and analysis, bioinformatics, and microscopy.

• Research Assistant

  • 2004 - 2005

  Examining a role of Cytosolic Linker Protein (CLIP-170) during phagocytosis in mouse macrophage cells. Involved transfection, microinjection, confocal microscopy, RNA interference, and protein analysis including protein blotting and immunocytochemistry using RAW264.7 cells.

• Teaching Assistant

  • Sep 2004 - Dec 2004

  Biology. 1st year. TA duties including assisting students with lab projects and marking lab reports.

• Research Assistant

  • 2002 - 2004

  Determining the nuclear localization and expression level of SMC II condensin molecule in Lilium longiflorum and genetic analysis of Arabidopsis thaliana mutants. Involved protein analysis including protein blotting and immunocytochemistry, and DNA analysis such as PCR.