Daniel Chen

Senior Research Associate at Innovo Therapeutics
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Contact Information
us****@****om
(386) 825-5501
Location
Rochester, New York, United States, US
Languages
  • Chinese Native or bilingual proficiency

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Research Associate
      • Oct 2022 - Present

      Working with a small team of biologist and chemist to develop bioassay and validate experiments for pushing compounds through the development pipeline for our small molecular inhibitors that aim to selectively degrade hard-to-drug targets in certain types of cancers. Working with a small team of biologist and chemist to develop bioassay and validate experiments for pushing compounds through the development pipeline for our small molecular inhibitors that aim to selectively degrade hard-to-drug targets in certain types of cancers.

    • United States
    • Government Administration
    • 1 - 100 Employee
    • Clinical Research Coordinator
      • Aug 2020 - Sep 2022

      Participated in the development of study-related clinical documents, including informed consent forms, site training materials, CRFs, clinical monitoring plans, source document templates, and data audit worksheets. Participated in the development of study-related clinical documents, including informed consent forms, site training materials, CRFs, clinical monitoring plans, source document templates, and data audit worksheets.

    • Undergraduate Research Assistant
      • Dec 2018 - Dec 2021

      - Further investigating possible tau clearance pathway earlier confirmed by the presence of BAG3 - Focusing on how BAG3 interacts with HSP70/HSC70 and TBC1D10B in regulating Rab35 through ESCRT pathway in an effort for tau aggregate clearance -Co-author paper, BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance (https://doi.org/10.1016/j.biopsych.2021.10.024) - Familiar with cell culturing, tissue dissection, BCA assay, Western-blotting, PCR, SDS-Page, Western Blotting, Immunohistochemistry, Immunocytochemistry, and Co-Immunoprecipitation. Show less

    • United States
    • Biotechnology Research
    • 500 - 600 Employee
    • Cardiovascular Drug Development Intern
      • Jun 2021 - Aug 2021

      - Worked with Cardiovascular Drug Development team in determining the efficacy of our antisense oligonucleotide in treating Anderson-Fabry's disease - Worked with Cardiovascular Drug Development team in determining the efficacy of our antisense oligonucleotide in treating Anderson-Fabry's disease

    • Events Services
    • 1 - 100 Employee
    • Procedural Data Validation Intern
      • Jun 2020 - Aug 2020

      - Worked with a large upstream processes team to complete deadlines in a time sensitive manner - Oversaw day to day operations and tasks virtually between lab staff and head scientist - Worked on identifying consistent errors in R with in house statistician and learned how to present data in a professional setting - Validated workplace procedures and protocols for errors and streamlined efficiency of research data while learning industry techniques - Worked with a large upstream processes team to complete deadlines in a time sensitive manner - Oversaw day to day operations and tasks virtually between lab staff and head scientist - Worked on identifying consistent errors in R with in house statistician and learned how to present data in a professional setting - Validated workplace procedures and protocols for errors and streamlined efficiency of research data while learning industry techniques

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Medical Scribe
      • Dec 2018 - Dec 2019

      - Worked alongside physicians and mid-level providers in the emergency departments of Rochester Regional Health Hospitals. - Fluent in the medical/hospital terminology that was needed to document a patient's visit. - On top my usual duties as a scribe I learned how a provider treat patients through imagining tests, lab tests, and physical exams. - Adept at juggling multiple tasks at once and extremely detailed note taker. - Worked alongside physicians and mid-level providers in the emergency departments of Rochester Regional Health Hospitals. - Fluent in the medical/hospital terminology that was needed to document a patient's visit. - On top my usual duties as a scribe I learned how a provider treat patients through imagining tests, lab tests, and physical exams. - Adept at juggling multiple tasks at once and extremely detailed note taker.

    • Undergraduate Research Assistant
      • Nov 2018 - Feb 2019

      - Attempted to identify the effect of various antibiotic stresses on the DNA sequence of Staphylococcus Aureus. - Use of CRISPR-Cas9 system to edit breaks in circular bacteria chromosomal DNA and introduce co-factors in off spring chromosomal DNA - Co-factors in from offspring DNA is able to induce cell death and prevent further infection of host - Attempted to identify the effect of various antibiotic stresses on the DNA sequence of Staphylococcus Aureus. - Use of CRISPR-Cas9 system to edit breaks in circular bacteria chromosomal DNA and introduce co-factors in off spring chromosomal DNA - Co-factors in from offspring DNA is able to induce cell death and prevent further infection of host

    • Hospital Intern
      • Jun 2017 - Aug 2017

      - Hands on training with assisting in procedures for root canals and wisdom teeth extraction. - Learned how to understand imaging test results (X-ray, MRI, CAT scan) - Worked on documenting patient procedures and updating patient charts - Hands on training with assisting in procedures for root canals and wisdom teeth extraction. - Learned how to understand imaging test results (X-ray, MRI, CAT scan) - Worked on documenting patient procedures and updating patient charts

    • Laboratory Technician
      • Nov 2016 - May 2017

      - Design and execute laboratory testing according standard procedures, make observations, interpret findings, and discuss with PI - Conducted tumor extraction from mice and performed statistical analysis on diameters - Responsible for taking care live bio-hazard samples - Organize and store all chemicals substances, fluids and compressed gases according to safety instructions - Design and execute laboratory testing according standard procedures, make observations, interpret findings, and discuss with PI - Conducted tumor extraction from mice and performed statistical analysis on diameters - Responsible for taking care live bio-hazard samples - Organize and store all chemicals substances, fluids and compressed gases according to safety instructions

Education

  • University of Rochester
    Bachelor of Science - BS, Major in Microbiological Sciences and Immunology, Minor in Chemistry
    2018 - 2022
  • University High School
    High School Diploma, Magna Cum Laude
    2014 - 2018

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