Daniel Chen
Senior Research Associate at Innovo Therapeutics- Claim this Profile
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Chinese Native or bilingual proficiency
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Bio
Experience
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Innovo Therapeutics
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Research Associate
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Oct 2022 - Present
Working with a small team of biologist and chemist to develop bioassay and validate experiments for pushing compounds through the development pipeline for our small molecular inhibitors that aim to selectively degrade hard-to-drug targets in certain types of cancers. Working with a small team of biologist and chemist to develop bioassay and validate experiments for pushing compounds through the development pipeline for our small molecular inhibitors that aim to selectively degrade hard-to-drug targets in certain types of cancers.
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Monroe County Health Department
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United States
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Government Administration
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1 - 100 Employee
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Clinical Research Coordinator
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Aug 2020 - Sep 2022
Participated in the development of study-related clinical documents, including informed consent forms, site training materials, CRFs, clinical monitoring plans, source document templates, and data audit worksheets. Participated in the development of study-related clinical documents, including informed consent forms, site training materials, CRFs, clinical monitoring plans, source document templates, and data audit worksheets.
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Undergraduate Research Assistant
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Dec 2018 - Dec 2021
- Further investigating possible tau clearance pathway earlier confirmed by the presence of BAG3 - Focusing on how BAG3 interacts with HSP70/HSC70 and TBC1D10B in regulating Rab35 through ESCRT pathway in an effort for tau aggregate clearance -Co-author paper, BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance (https://doi.org/10.1016/j.biopsych.2021.10.024) - Familiar with cell culturing, tissue dissection, BCA assay, Western-blotting, PCR, SDS-Page, Western Blotting, Immunohistochemistry, Immunocytochemistry, and Co-Immunoprecipitation. Show less
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Ionis Pharmaceuticals, Inc.
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United States
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Biotechnology Research
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500 - 600 Employee
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Cardiovascular Drug Development Intern
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Jun 2021 - Aug 2021
- Worked with Cardiovascular Drug Development team in determining the efficacy of our antisense oligonucleotide in treating Anderson-Fabry's disease - Worked with Cardiovascular Drug Development team in determining the efficacy of our antisense oligonucleotide in treating Anderson-Fabry's disease
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Pfizer
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Events Services
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1 - 100 Employee
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Procedural Data Validation Intern
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Jun 2020 - Aug 2020
- Worked with a large upstream processes team to complete deadlines in a time sensitive manner - Oversaw day to day operations and tasks virtually between lab staff and head scientist - Worked on identifying consistent errors in R with in house statistician and learned how to present data in a professional setting - Validated workplace procedures and protocols for errors and streamlined efficiency of research data while learning industry techniques - Worked with a large upstream processes team to complete deadlines in a time sensitive manner - Oversaw day to day operations and tasks virtually between lab staff and head scientist - Worked on identifying consistent errors in R with in house statistician and learned how to present data in a professional setting - Validated workplace procedures and protocols for errors and streamlined efficiency of research data while learning industry techniques
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ScribeAmerica
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United States
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Hospitals and Health Care
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700 & Above Employee
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Medical Scribe
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Dec 2018 - Dec 2019
- Worked alongside physicians and mid-level providers in the emergency departments of Rochester Regional Health Hospitals. - Fluent in the medical/hospital terminology that was needed to document a patient's visit. - On top my usual duties as a scribe I learned how a provider treat patients through imagining tests, lab tests, and physical exams. - Adept at juggling multiple tasks at once and extremely detailed note taker. - Worked alongside physicians and mid-level providers in the emergency departments of Rochester Regional Health Hospitals. - Fluent in the medical/hospital terminology that was needed to document a patient's visit. - On top my usual duties as a scribe I learned how a provider treat patients through imagining tests, lab tests, and physical exams. - Adept at juggling multiple tasks at once and extremely detailed note taker.
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Undergraduate Research Assistant
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Nov 2018 - Feb 2019
- Attempted to identify the effect of various antibiotic stresses on the DNA sequence of Staphylococcus Aureus. - Use of CRISPR-Cas9 system to edit breaks in circular bacteria chromosomal DNA and introduce co-factors in off spring chromosomal DNA - Co-factors in from offspring DNA is able to induce cell death and prevent further infection of host - Attempted to identify the effect of various antibiotic stresses on the DNA sequence of Staphylococcus Aureus. - Use of CRISPR-Cas9 system to edit breaks in circular bacteria chromosomal DNA and introduce co-factors in off spring chromosomal DNA - Co-factors in from offspring DNA is able to induce cell death and prevent further infection of host
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Hospital Intern
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Jun 2017 - Aug 2017
- Hands on training with assisting in procedures for root canals and wisdom teeth extraction. - Learned how to understand imaging test results (X-ray, MRI, CAT scan) - Worked on documenting patient procedures and updating patient charts - Hands on training with assisting in procedures for root canals and wisdom teeth extraction. - Learned how to understand imaging test results (X-ray, MRI, CAT scan) - Worked on documenting patient procedures and updating patient charts
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Laboratory Technician
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Nov 2016 - May 2017
- Design and execute laboratory testing according standard procedures, make observations, interpret findings, and discuss with PI - Conducted tumor extraction from mice and performed statistical analysis on diameters - Responsible for taking care live bio-hazard samples - Organize and store all chemicals substances, fluids and compressed gases according to safety instructions - Design and execute laboratory testing according standard procedures, make observations, interpret findings, and discuss with PI - Conducted tumor extraction from mice and performed statistical analysis on diameters - Responsible for taking care live bio-hazard samples - Organize and store all chemicals substances, fluids and compressed gases according to safety instructions
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Education
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University of Rochester
Bachelor of Science - BS, Major in Microbiological Sciences and Immunology, Minor in Chemistry -
University High School
High School Diploma, Magna Cum Laude