Experience

Mutabilis

• Biotechnology Research
• 1 - 100 Employee

• Head of biochemistry/pharmacology

  • Jun 2018 - Present

  Study of novel anti-infectives against Gram-negative multiresistant bacteria: in vitro stability and biochemical activity, in vivo tolerability, efficacy, pharmacokinetics and pharmacodynamics External collaborations: outsourcing in CROs, involvement in 2 European collaborative programs aiming at the preclinical validation of drug candidates towards phase I clinical trials Laboratory management, interface with the regulatory authorities, Team management (3): assay design… Show more Study of novel anti-infectives against Gram-negative multiresistant bacteria: in vitro stability and biochemical activity, in vivo tolerability, efficacy, pharmacokinetics and pharmacodynamics External collaborations: outsourcing in CROs, involvement in 2 European collaborative programs aiming at the preclinical validation of drug candidates towards phase I clinical trials Laboratory management, interface with the regulatory authorities, Team management (3): assay design, planning incl. night shift, skill development

• Head of biochemistry/microbiology

  • May 2012 - May 2018

  Studies of biochemical and microbiological activities of novel anti-infectives: - Development of a full set of assays for antibiotic compounds - Profiling of medicinal chemistry molecules, edition of structure-activity tables Laboratory management: - Bacterial strain collection, compound and database management - Team management (4) - Operational qualification and maintenance of micropipettes, liquid handlers, microplate readers

• Head of HIV biochemistry

  • Jan 2009 - May 2012

  Study of novel anti-AIDS/HIV agents, a project that led to the discovery of the first-in-man HIV-1 integrase allosteric inhibitor. Biochemical assay development and high-throughput screening Management of the chemical library Team management: 2 technicians, 2 graduate students



Hybrigenics Services

• France
• Biotechnology
• 1 - 100 Employee

• Screening engineer

  • Feb 2008 - Dec 2008

  Protein production, biochemical assay setup and high throughput screening of chemical libraries to identify inihbitors of protein-protein interactions Protein production, biochemical assay setup and high throughput screening of chemical libraries to identify inihbitors of protein-protein interactions



Hybrigenics Services

• France
• Biotechnology
• 1 - 100 Employee

• Process engineer

  • Jan 2007 - Dec 2007

  Assay development (microbiology, biochemistry, molecular biology) for the ISO9001-certified protein-protein interaction high throughput screening platform. Quality management. Assay development (microbiology, biochemistry, molecular biology) for the ISO9001-certified protein-protein interaction high throughput screening platform. Quality management.