Cyprian Winogradow

Bioinformatician at Ardigen
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London, England, United Kingdom, UK

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Experience

    • Poland
    • Biotechnology Research
    • 100 - 200 Employee
    • Bioinformatician
      • Mar 2020 - Present
    • Laboratory Technician
      • Jun 2018 - Sep 2018

      I was carrying out experiments in which synthetic inhibitors of Uracil-DNA glycosylase (UDG) were to be synthesized, protein crystals acquired to be further analyzed using X-ray crystallography. Bacteria colonies acquired via classic restriction ligation cloning were used for expressing cloned vectors to synthesize proteins that could act as UDG inhibitors. Experiments were designed and supervised by Doctor Renos Savva. I was carrying out experiments in which synthetic inhibitors of Uracil-DNA glycosylase (UDG) were to be synthesized, protein crystals acquired to be further analyzed using X-ray crystallography. Bacteria colonies acquired via classic restriction ligation cloning were used for expressing cloned vectors to synthesize proteins that could act as UDG inhibitors. Experiments were designed and supervised by Doctor Renos Savva.

    • Laboratory Technician
      • Jun 2017 - Sep 2017

      I learned how to manufacture bacteriophage therapeutics, including setting up and maintaining cell and bacteriophage cultures or acquiring appropriate bacteriophage concentration (phage titer) necessary for phage therapeutics. Additionally, under the supervision of Doctor Ryszard Miedzybrodzki, I was responsible for carrying out an investigation on a correlation between phage-mediated bacteria lysis and additional therapeutics used. Routine Test Dilution, spectrophotometry and both fluorescent and electron microscopy were amongst necessary tools used for this experiment. Moreover, I have been involved in writing a scientific review on the topic of antimicrobial resistance. Show less

    • Poland
    • Medical Equipment Manufacturing
    • 1 - 100 Employee
    • Quality Control Assistant
      • Jul 2014 - Sep 2014

      I assisted at quality control of radiopharmaceuticals produced at the centre, which were later used in hospitals and biomedical research institutions in Warsaw and the surrounding area. I learned how to use devices such as chromatographs and spectrometers, necessary for quality control. I assisted at quality control of radiopharmaceuticals produced at the centre, which were later used in hospitals and biomedical research institutions in Warsaw and the surrounding area. I learned how to use devices such as chromatographs and spectrometers, necessary for quality control.

    • Laboratory Assistant
      • Jun 2014 - Jul 2014

      I learned scientific tools necessary for protein purification and crystallisation - including AKTA chromatography and sampling of acquired protein crystals for X-ray diffraction I learned scientific tools necessary for protein purification and crystallisation - including AKTA chromatography and sampling of acquired protein crystals for X-ray diffraction

    • Student Researcher
      • Jun 2013 - Aug 2013

      I had the opportunity to use some laboratory space at the Warsaw University of Life Sciences to carry out my first official research project titled ‘The influence of chemical substances extracted from leaves of Ailanthus altissima on germination of Sinapis alba’s seeds’ I have learnt how to prepare my own experiment, analyze data and present the results of my work in front of others for their evaluation. Additionally, I had to meet deadlines and organize both my workplace and personal timetable so that the investigation finished before the specified time. Show less

Education

  • Birkbeck, University of London
    Master of Science - MS, Bioinformatics
    2018 - 2019
  • UCL
    Bachelor of Science - BS, Biomedical Sciences, General
    2014 - 2018

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