Chun-Tien (Jimmy) Kuo
Gene Therapy Delivery Scientist at Regeneron- Claim this Profile
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Bio
Experience
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Regeneron
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United States
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Biotechnology
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700 & Above Employee
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Gene Therapy Delivery Scientist
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Aug 2022 - Present
Sr Scientist, In vivo Engineering and Non-viral Delivery Technologies, Regeneron Genetic Medicines. Lipid Nanoparticle Formulation Discovery, Development, Processing, and Engineering. Gene Editing and Nucleic Acid Delivery. Sr Scientist, In vivo Engineering and Non-viral Delivery Technologies, Regeneron Genetic Medicines. Lipid Nanoparticle Formulation Discovery, Development, Processing, and Engineering. Gene Editing and Nucleic Acid Delivery.
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The Ohio State University College of Pharmacy
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United States
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Higher Education
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100 - 200 Employee
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Graduate Research Associate
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Jan 2018 - Aug 2022
Ph.D. Candidate, Division of Pharmaceutics and Pharmacology.Lipid Nanoparticle Formulation Development, Processing, Engineering, and Nucleic Acid Delivery.Advisor: Robert J Lee, Ph.D.> Protein-drug conjugates: Synthesis and Characterization (collaboration with Dr. Terry Williams, Radiation Oncology, City of Hope).> Lipid nanoparticle formulations for oligonucleotide (including ASO, miRNA, siRNA), messenger RNA (mRNA) and/or small molecular drug delivery: Development, Characterization, and Efficacy Assessment.> Develop and evaluate lipid nanoparticle formulations for oligonucleotides (including antisense oligonucleotides, miRNA, and siRNA) and messenger RNA (mRNA) delivery for anticancer therapeutics and virus vaccines, in collaboration with a biotech company.> Develop and evaluate lipid nanoemulsion-based formulations for oligonucleotides and messenger RNA (mRNA) delivery as well as cancer and virus vaccines.> Nanoparticle formulation scale-up production: Process Development and Optimization (collaboration with Dr. Ramiro Garzon, Hematology, OSUCCC).> Analytical assay development (ELISA) and validation for anti-drug antibody detection. Show less
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Graduate Teaching Associate
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Aug 2017 - Dec 2018
Worked as the teaching associate for PHR4600 Undergraduate Pharmaceutical Sciences Laboratory, under the supervision of Dr. Katie Summers.> Led the lab sessions, including teaching basic background theories and demonstrating technical skills, 24+ undergraduates per time.> Held TA hours guiding students in lecture materials, report writing, and data processing.> Supported lab manager in lab session preparation and student report grading.
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Yilan County Fire Bureau
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Yilan County, Taiwan
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消防替代役 Substitute Military Service
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Aug 2016 - Jul 2017
Substitute Military Service, Emergency Medical Specialty. > Worked as an EMT to support patients during the ways to ERs. Substitute Military Service, Emergency Medical Specialty. > Worked as an EMT to support patients during the ways to ERs.
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Adimmune Corp (4142)
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Biotechnology Research
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1 - 100 Employee
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Summer Intern
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Jul 2015 - Aug 2015
Summer intern in the R&D department, under the supervision of Dr. Wan-hsing Liu. > Took PIC/S GMP Training for new employees: Passed. > Worked on recombinant viral protein purification and in vivo viral titer evaluation. > Regulatory documents reading and presentation. Summer intern in the R&D department, under the supervision of Dr. Wan-hsing Liu. > Took PIC/S GMP Training for new employees: Passed. > Worked on recombinant viral protein purification and in vivo viral titer evaluation. > Regulatory documents reading and presentation.
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Education
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The Ohio State University
Doctor of Philosophy - PhD, Pharmaceutics -
The Ohio State University
Graduate Minor, Applied Clinical and Preclinical Research -
National Taiwan University
Bachelor of Science (BS), Chemical Engineering