Christopher Stefan

Chief, Developmental Diagnostics, Diagnostics Systems Division at USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases
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Contact Information
us****@****om
(386) 825-5501
Location
Columbia, Maryland, United States, US

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Experience

    • United States
    • Research Services
    • 700 & Above Employee
    • Chief, Developmental Diagnostics, Diagnostics Systems Division
      • Jul 2022 - Present

    • Research Scientist IV
      • Nov 2017 - Jan 2023

    • National Research Associate, Post Doctoral Student
      • Aug 2013 - Jan 2023

      Targeted next-generation sequencing of infectious agents

    • Principle Investigator / Research Scientist IV
      • 2017 - Jan 2023

    • United States
    • Higher Education
    • 700 & Above Employee
    • Doctoral Student
      • 2008 - Jul 2013

      During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as… Show more During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as adjuncts to existing fungal therapies Show less During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as… Show more During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as adjuncts to existing fungal therapies Show less

    • Research Associate
      • 2005 - 2007

      Produce and manage microarray slides for the research community DNA and RNA preparation for microarrays involved in various research projects Produce and manage microarray slides for the research community DNA and RNA preparation for microarrays involved in various research projects

    • Research Fellow
      • 2004 - 2005

      Bacterial II-hybrid and yeast II-hybrid analysis of protein-protein interactions Use Gateway cloning technologies to design plasmids Protein purification using nickel-affinity columns Bacterial II-hybrid and yeast II-hybrid analysis of protein-protein interactions Use Gateway cloning technologies to design plasmids Protein purification using nickel-affinity columns

Education

  • The Johns Hopkins University
    Doctor of Philosophy (Ph.D.), Cellular, Molecular, Developmental Biology and Biophysics
    2008 - 2013
  • University of Maryland College Park
    Bachelor of Science (BS), Cellular and Molecular Biology
    2001 - 2005

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