Christopher Stefan
Chief, Developmental Diagnostics, Diagnostics Systems Division at USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases- Claim this Profile
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Bio
Experience
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USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases
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United States
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Research Services
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700 & Above Employee
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Chief, Developmental Diagnostics, Diagnostics Systems Division
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Jul 2022 - Present
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Research Scientist IV
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Nov 2017 - Jan 2023
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National Research Associate, Post Doctoral Student
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Aug 2013 - Jan 2023
Targeted next-generation sequencing of infectious agents
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Principle Investigator / Research Scientist IV
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2017 - Jan 2023
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The Johns Hopkins University
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United States
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Higher Education
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700 & Above Employee
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Doctoral Student
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2008 - Jul 2013
During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as… Show more During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as adjuncts to existing fungal therapies Show less During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as… Show more During my thesis work I characterized two novel transmembrane proteins and studied their effects on calcium signaling and cell death in Saccharomyces cerevisiae. I classified these two proteins as putative low-affinity potassium channels involved in the electrochemical activation of voltage-gated calcium channels located on the yeast cell membrane. I placed these proteins at the apex of a cell death pathway conserved in pathogenic fungi, making them possible candidates for drug discovery as adjuncts to existing fungal therapies Show less
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Research Associate
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2005 - 2007
Produce and manage microarray slides for the research community DNA and RNA preparation for microarrays involved in various research projects Produce and manage microarray slides for the research community DNA and RNA preparation for microarrays involved in various research projects
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Research Fellow
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2004 - 2005
Bacterial II-hybrid and yeast II-hybrid analysis of protein-protein interactions Use Gateway cloning technologies to design plasmids Protein purification using nickel-affinity columns Bacterial II-hybrid and yeast II-hybrid analysis of protein-protein interactions Use Gateway cloning technologies to design plasmids Protein purification using nickel-affinity columns
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Education
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The Johns Hopkins University
Doctor of Philosophy (Ph.D.), Cellular, Molecular, Developmental Biology and Biophysics -
University of Maryland College Park
Bachelor of Science (BS), Cellular and Molecular Biology