Experience

LifeArc

• United Kingdom
• Non-profit Organizations
• 200 - 300 Employee

• Chronic Respiratory Infection Translational Challenge Portfolio Manager

  • Jul 2023 - Present

  Edinburgh, Scotland, United Kingdom

• Principal Project Manager

  • Jan 2023 - Jul 2023

  Edinburgh, Scotland, United Kingdom LifeArc’s mission is to unlock the potential of advancing early scientific discoveries to the point where they can be developed into the next generation of diagnostics, treatments and cures. We are committing to invest up to £1.3 billion by 2030 to transform promising life science ideas into life-changing medical breakthroughs for patients, faster. Making life science life changing. To help achieve this ambitious goal we are launching translational challenges (TC) where we will be mobilising… Show more LifeArc’s mission is to unlock the potential of advancing early scientific discoveries to the point where they can be developed into the next generation of diagnostics, treatments and cures. We are committing to invest up to £1.3 billion by 2030 to transform promising life science ideas into life-changing medical breakthroughs for patients, faster. Making life science life changing. To help achieve this ambitious goal we are launching translational challenges (TC) where we will be mobilising collaborations, working with others to connect and unlock the potential of scientific innovations to solve complex healthcare problems. One of these challenges is in the area of chronic respiratory infection (CRI). As the programme manager for the CRI TC, I am working closely alongside the challenge leader, Katy Kettleborough, to help invest up to £100 million by 2030 to transform healthcare for people living with bronchiectasis and cystic fibrosis by developing new diagnostics, treatments and other technologies in partnership with others. Our goal is to enable people living with these conditions to live longer with improved quality of life by ending the vicious cycle of infection, inflammation and permanent lung damage. #LifeArc2030 #Bronchiectasis #CysticFibrosis #Lunginfection #LifeScience. My role involves ensuring the programme has a clear framework and strategy to support delivery of our key workstreams; early detection, right diagnosis and better treatments. I am responsible for monitoring and evaluating the outputs, ensuring the team are on track to meet milestones, reporting on risks and issues to delivery and ensuring we are focused on hearing from patients with chronic respiratory infections. Other responsibilities include resource mapping, budget control, summarising on new opportunities and ensuring senior management and the board of trustees are fully aware on activities. I am also involved in shaping the strategy for the future delivery in this exciting area.

• Senior Project Manager

  • Oct 2021 - Jan 2023

  Edinburgh, Scotland, United Kingdom As a Senior Project Manager my role is primarily involved in the management, strategic implementation and successful completion of the diagnostic portfolio of projects, with responsibilities also extending to our broader strategic priorities across translational science and funding. Ensures application of effective project management governance, processes and systems across Diagnostics, demonstrating best practice for successful delivery and to ensure work is compliant with all relevant… Show more As a Senior Project Manager my role is primarily involved in the management, strategic implementation and successful completion of the diagnostic portfolio of projects, with responsibilities also extending to our broader strategic priorities across translational science and funding. Ensures application of effective project management governance, processes and systems across Diagnostics, demonstrating best practice for successful delivery and to ensure work is compliant with all relevant internal policies and ISO 13485 regulations. Acts as a key business partner to the Head of Diagnostics, Head of Assay Development, Principal Project Manager in Translational Science, the Head of Corporate & Portfolio Project Management and the Executive Director of Translational Science. LifeArc is an independent life science medical research charity committed to improving positive patient outcomes by driving medical innovation through our own research and work with a range of partners from academic, biotechnology, pharmaceutical, and charity organisations. Our goal is to move promising medical research forward into viable and accessible patient treatments through collaboration with scientists in diagnostics, therapies, enhancing and protecting innovation and advancing translational research.



AliveDx

• Switzerland
• Medical Device
• 100 - 200 Employee

• Project Manager

  • Oct 2017 - Oct 2021

  Edinburgh, United Kingdom Having moved into a role of Project Manager on the Serological Disease Screening project I now manage the team that are developing the next generation disease screening product for Quotient. Building on my experience as a Senior Scientist at Quotient I am now using this technical knowledge and expertise to lead and strategically plan the next phase of the Disease Screening microarray product that Quotient are aiming to launch. I work closely with colleagues in Edinburgh and Switzerland… Show more Having moved into a role of Project Manager on the Serological Disease Screening project I now manage the team that are developing the next generation disease screening product for Quotient. Building on my experience as a Senior Scientist at Quotient I am now using this technical knowledge and expertise to lead and strategically plan the next phase of the Disease Screening microarray product that Quotient are aiming to launch. I work closely with colleagues in Edinburgh and Switzerland to plan and execute key studies to drive this project forward within the required timelines. I also collaborate and communicate with external partners who are key suppliers or stakeholders in this project. This exciting new role is allowing me to utilise my excellent communication, planning and negotiating skills with enthusiasm and tenacity to meet the required deadlines Led the team to CE Mark submission in July 2019 which was successfully approved in February 2020.

• Senior Development Scientist

  • Jun 2012 - Oct 2017

  Edinburgh, United Kingdom •Quotient is a major bio-manufacturing organisation, supplying vital products to hospitals, blood services and healthcare companies. The product range includes in vitro diagnostics for immunohaematology, immunology and haematology. Many products incorporate polyclonal antisera or monoclonal antibodies. • Innovated, developed and successfully implemented assays used to characterize antibodies purified from cell culture material. Adapt technical protocols independently according to… Show more •Quotient is a major bio-manufacturing organisation, supplying vital products to hospitals, blood services and healthcare companies. The product range includes in vitro diagnostics for immunohaematology, immunology and haematology. Many products incorporate polyclonal antisera or monoclonal antibodies. • Innovated, developed and successfully implemented assays used to characterize antibodies purified from cell culture material. Adapt technical protocols independently according to experimental needs. • Proficient in technologies useful in antibody determination including SDS-PAGE, Western blotting, ELISA etc. • Provide written and oral presentations of results to members of the group, project teams and senior management. Provide decision-enabling data supporting the advancement of projects. • Acts as a project lead providing scientific leadership, ensuring that projects are conducted according to the agreed timelines and the required quality and have the tenacity to drive projects through the different stages to successful completion. • Generated new processes for streamlining workflow and for analysis and storage of data generated across multiple teams. • Ensures adherence to quality standards as well as proper documentation of experimental results. • Provide support to other development scientists, with training and mentoring of junior staff.



Centre for Molecular Medicine, MRC, IGMM

• Research Assistant

  • Nov 2010 - Jun 2012

  Working in the Medical Genetics section under the umbrella of Psychiatric Genetics in Professor David Porteous's group we are studying the DISC1 gene (Disrupted In SChizophrenia 1) and determining the genetic and biochemical pathways surrounding this genetic risk factor. Developed experience in procedures for cell biology and protein biochemistry which include: 1. Generation of protein probes using GST-tagged expression constructs 2. Probing of protein arrays to detect… Show more Working in the Medical Genetics section under the umbrella of Psychiatric Genetics in Professor David Porteous's group we are studying the DISC1 gene (Disrupted In SChizophrenia 1) and determining the genetic and biochemical pathways surrounding this genetic risk factor. Developed experience in procedures for cell biology and protein biochemistry which include: 1. Generation of protein probes using GST-tagged expression constructs 2. Probing of protein arrays to detect protein-protein interactions 3. Transformation of cells with subsequent plasmid DNA purification 4. Transfection of cells for overexpression of DNA constructs 5. Cell culture 6. Immunoprecipitation 7. SDS gel electrophoresis and western blotting Show less



Merck

• DMPK & Bioanalytical Scientist

  • Apr 2005 - Nov 2010

  Merck Expertise in protein binding, blood-plasma partitioning assays, in-vitro drug metabolism and in vitro to in-vivo extrapolation (IVIVE). Leading development, validation and implementation of protein binding assays which increased throughput 5 fold. Managed the culture and use of Caco-2 cells for the measurement of drug permability and efflux. Trained and mentored staff on instruments, databases and protocols. Supervised and coached a pharmacology university student in gaining a… Show more Expertise in protein binding, blood-plasma partitioning assays, in-vitro drug metabolism and in vitro to in-vivo extrapolation (IVIVE). Leading development, validation and implementation of protein binding assays which increased throughput 5 fold. Managed the culture and use of Caco-2 cells for the measurement of drug permability and efflux. Trained and mentored staff on instruments, databases and protocols. Supervised and coached a pharmacology university student in gaining a first class project for their degree Took the initiative to strengthen own bioanalytical knowledge, following merger of DMPK & Bioanalysis sections, to deliver high quality input into optimisation of DMPK assay protocols and data treatment including learning new techniques in LC-MS/MS analysis for in-vitro DMPK assays. Show less



IQVIA

• United States
• Hospitals and Health Care
• 700 & Above Employee

• DMPK Scientist

  • Sep 2002 - Apr 2005

  Working on a variety of discovery and development contract projects allowed me to gain a wide skills and knowledge set in in-vitro DMPK