Chia-Hong Tsai
Chief Technology Officer at Bota Biosciences- Claim this Profile
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Bio
Experience
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Bota Biosciences
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United States
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Biotechnology
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1 - 100 Employee
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Chief Technology Officer
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Jun 2020 - 3 years 7 months
Bota Bio Raises $100 Million Series B Financing to Advance Sustainable Biomanufacturing https://www.prnewswire.com/news-releases/bota-bio-raises-100-million-series-b-financing-to-advance-sustainable-biomanufacturing-301343566.html BASF invests in biotechnology start-up Bota Bio https://www.basf.com/global/en/media/news-releases/2021/03/p-21-158.html C&EN’s 2021 10 Start-Ups to Watch https://cen.acs.org/business/start-ups/CENs-2021-10-Start-Ups-to-Watch-cleantech/99/i42
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Amyris
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United States
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Biotechnology Research
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700 & Above Employee
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Scientist, Metabolic Engineering
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Aug 2015 - May 2020
• Project Lead of a high-valued nutraceutical molecule. • Biology Group Lead of a natural sweetener molecule. • Co-inventor of three patent applications.
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Biology Intern
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May 2015 - Aug 2015
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Michigan State University
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United States
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Higher Education
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700 & Above Employee
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Graduate Assistant
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Sep 2009 - Dec 2014
• Discovered a transcription factor of triacylglycerol metabolism and its link with cell cycle control to uncouple the inverse relationship between biomass production and energy compound accumulation in microalgae – led to a first-author publication in the Proceedings of the National Academy of Sciences. • Developed protocols to isolate native protein complexes from lipid droplets and conducted native PAGE and LC-MS/MS-based proteomics to characterize the machinery for enzyme arrays to… Show more • Discovered a transcription factor of triacylglycerol metabolism and its link with cell cycle control to uncouple the inverse relationship between biomass production and energy compound accumulation in microalgae – led to a first-author publication in the Proceedings of the National Academy of Sciences. • Developed protocols to isolate native protein complexes from lipid droplets and conducted native PAGE and LC-MS/MS-based proteomics to characterize the machinery for enzyme arrays to assemble on lipid droplets – led to a first-author publication in The Plant Journal. • Collaborated with two bioinformatics groups to analyze transcriptomic datasets for metabolic engineering – led to a first-author publication in The Plant Physiology. • Co-developed a transformation protocol for industrial microalga Nannochloropsis oceanica and invented a high-throughput screen for high-oil strains – led to a publication in PLoS Genetics. Show less
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Lab Manager/Research Assistant
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2007 - 2009
Taipei City, Taiwan • Studied the molecular biology of plant-microbe interaction – led to 5 publications (1 first-author). .• Helped the PI who did not speak Chinese establish a new lab in a Chinese-speaking environment.
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Second Lieutenant
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2005 - 2007
Kinmen County, Taiwan Led a platoon of 100 soldiers in active duty to reduce smuggling and illegal immigration.
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Education
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Michigan State University
Doctor of Philosophy (Ph.D.), Plant Biology, Biochemistry & Molecular Biology -
Delft University of Technology
Certificate, BioTech Delft Advanced Course, Microbial Physiology and Fermentation Technology -
National Taiwan University
Bachelor's Degree, Life Science