Experience

F-star, an invoX company

• United Kingdom
• Biotechnology
• 1 - 100 Employee

• Scientist, Drug Discovery

  • Aug 2022 - Present



The Ohio State University

• United States
• Higher Education
• 700 & Above Employee

• Graduate Research Associate

  • Aug 2016 - Jul 2022

  • Designed and generated 62 positional libraries of an RNA binding protein and interpreted its sequence-functional landscape via Next Generation Sequencing (NGS). Received presentation opportunities at multiple platforms, including in Gordon, ACS, and Protein Society • Optimized high-throughput expression and purification of the positional libraries and identified multiple point-mutants with thermal stability higher than WT• Identified amino acids responsible for the binding of notch ligand by protein sequence and structural analysis• Optimized large-scale expression and purification protocol of notch ligands in the bacterial system to achieve 5x higher yield and obtained 2x higher resolution NMR• Cloned and established mammalian expression system in Expi 293F cell line for notch ligands to determine binding affinity using SPR• Coached six PhD. students in experiment design, lab techniques and data interpretation• Mentored four undergraduates in acquiring biochemistry lab techniques, designing experiments, writing abstracts and completing poster presentations Show less

• Graduate Teaching Associate

  • Aug 2016 - Jul 2022

  • Received nomination for the prestigious Graduate Associate Teaching Award (GATA) at OSU• Taught weekly labs and recitations to multiple classes of 20-30 undergraduates each for 11 semesters, including introductory biochemistry, Biology and General Chemistry• Developed teaching material and strategies, prepared exam questions, led TA meetings and shared best practices other than regular duties of grading, attending office hours, staff meetings, and proctoring exams



Indian Institute of Science (IISc)

• India
• Research
• 700 & Above Employee

• Research Intern

  • May 2015 - Apr 2016

  • Master's Thesis Project • Synthesized and tested a small organic peroxynitrite donor on pathogenic Mycobacterium tuberculosis and clinical strains of Multi-Drug & Extreme Drug-Resistant Tuberculosis as a therapeutic molecule in BSL-3 facility. • Master's Thesis Project • Synthesized and tested a small organic peroxynitrite donor on pathogenic Mycobacterium tuberculosis and clinical strains of Multi-Drug & Extreme Drug-Resistant Tuberculosis as a therapeutic molecule in BSL-3 facility.



University of Minnesota

• United States
• Higher Education
• 700 & Above Employee

• Research Scholar

  • May 2014 - Jul 2014

  • Khorana Scholar for 2014 • Synthesized a tetra acetylated histone peptide using solid-phase peptide synthesis. • Optimised expression and purification protocol for protein Bromodomain and dimerized it using bio-conjugation of alkyne and azide groups in the enzymatic reaction. • Khorana Scholar for 2014 • Synthesized a tetra acetylated histone peptide using solid-phase peptide synthesis. • Optimised expression and purification protocol for protein Bromodomain and dimerized it using bio-conjugation of alkyne and azide groups in the enzymatic reaction.



National Chemical Laboratory

• Research Services
• 700 & Above Employee

• Summer Intern

  • Jun 2013 - Jul 2013