Charles Saginario

Vice President of External R&D Operations at Curie.Bio
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Contact Information
us****@****om
(386) 825-5501
Location
Downingtown, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Vice President of External R&D Operations
      • Aug 2023 - 5 months

      At Curie, my role includes developing internal processes so that Curie can build and manage the very best strategic relationships with all of our external execution partners and thus provide the very best infrastructure to the Founders. I also work closely with both the CSO organization and the Founders to make use of these strategic partnerships to help the Founders generate the best results possible so that they are able to focus on completing an awesome Series A.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Executive Director, Head of Operations and External Partnerships
      • Jul 2017 - Jul 2023

      Wilmington, Delaware Biology Operations responsibilities include identifying, validating and implementing commercial and academic external technology, coordinating internal review, approval and execution of legal contracts including scientific research agreements, vendor work orders, master service agreements, licenses, data privacy assessments, capital equipment purchases and associated service contracts for all of Incyte Research Institute. Manage all biomarker data across Incyte programs; Management of Sample… Show more Biology Operations responsibilities include identifying, validating and implementing commercial and academic external technology, coordinating internal review, approval and execution of legal contracts including scientific research agreements, vendor work orders, master service agreements, licenses, data privacy assessments, capital equipment purchases and associated service contracts for all of Incyte Research Institute. Manage all biomarker data across Incyte programs; Management of Sample Coordination team, which receives, aliquots, ships and stores samples used for biomarker analysis across all Incyte programs; Management of the Translational Sciences Clinical Study Start Team which works closely with with central labs, clinical, operations and data management to develop and review clinical study protocols, amendments and associated study documentation; Management of Incyte Library Services; Show less

    • United States
    • Pharmaceutical Manufacturing
    • 300 - 400 Employee
    • Director Biologics and Biomarkers
      • Mar 2016 - Jul 2017

      Exton, PA The Frontage Biologics and Biomarkers group supports large molecule assay development, assay validation and sample analysis. We have a current CLIA certification, PA state DOH certification, and we are GLP compliant. Services include pharmacokinetics assays, immunogenicity (ADA, NAb) and Biomarkers.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Senior Scientist, Molecular Operations
      • Jun 2013 - Mar 2016

      Greater Philadelphia Area Molecular diagnostic assay development around circulating tumor cells.

    • United States
    • Pharmaceutical Manufacturing
    • 300 - 400 Employee
    • Group Leader for Pharmacogenomics
      • Oct 2005 - Jun 2013

      Newark, DE Group Leader for Pharmacogenomics and Molecular Bioanalysis at QPS Scientific and technical lead for various biomarker projects within the Department of Translational Medicine including pharmacogenomics, protein biomarkers, gene expression analysis, molecular bioanalysis and oligonucleotide hybridization ELISAs. Responsibilities include both bench work and project management.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Associate
      • Sep 2004 - Oct 2005

      Department of Physiology

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Associate
      • Mar 2002 - Sep 2004

      Department of Oncology Work focused on leukemia-associated reciprocal translocations of the MLL gene. Specifically examined the effect of DNA topoisomerase II inhibitors on the association of DNA-topoisomerase II with DNA (specifically the MLL gene) in hematopoietic stem cells and numerous leukemic cell lines via a combination of cell based assays, real-time PCR and custom microarrays using a novel platform.

    • Ireland
    • Business Consulting and Services
    • 700 & Above Employee
    • Consultant
      • Feb 2001 - Feb 2002

      Pharmaceutical and Medical Devices; Strategy Work focused on identifying problems and developing strategies and solutions in the area of research and development for the pharmaceutical and biotechnology industry.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Research Scientist
      • Jul 1998 - Feb 2001

      Womens Health; Bone Biology Group Projects focused on the identification of new gene targets for the treatment of osteoporosis. Examined the osteoblast-specific transcription factor Cbfa1 and a variety of signal transduction pathways.

Education

  • Yale University School of Medicine
    Ph.D., Molecular Cell Biology
    1992 - 1998
  • Rensselaer Polytechnic Institute
    BS, Biology
    1988 - 1992
  • Bronx Science
    1984 - 1988

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