Experience

NovoBiotic Pharmaceuticals

• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Microbiologist

  • Sep 2013 - Present

  Working to discover novel antibiotics from soil microbes by using proprietary technology (the “ichip”) to cultivate bacteria that were previously uncultivable in a laboratory setting. Responsible for running secondary assays on any compounds discovered. • Maintain 3T3 and HepG2 cell lines and use them to determine if a compound is cytotoxic • Run MICs and MBCs on compounds received with a variety of clinical isolates • Run endotoxin assays, DNA binding assays, hemolysis assays, post… Show more Working to discover novel antibiotics from soil microbes by using proprietary technology (the “ichip”) to cultivate bacteria that were previously uncultivable in a laboratory setting. Responsible for running secondary assays on any compounds discovered. • Maintain 3T3 and HepG2 cell lines and use them to determine if a compound is cytotoxic • Run MICs and MBCs on compounds received with a variety of clinical isolates • Run endotoxin assays, DNA binding assays, hemolysis assays, post antibiotic effect assays, time kill curves, drug combination studies on compounds of interest • Isolate bacteria from terrestrial soils using in situ cultivation methods developed at NovoBiotic • Responsible for running PCR and gel electrophoresis on bacterial strains of interest for sequencing purposes • Responsible for experimental design and troubleshooting Show less Working to discover novel antibiotics from soil microbes by using proprietary technology (the “ichip”) to cultivate bacteria that were previously uncultivable in a laboratory setting. Responsible for running secondary assays on any compounds discovered. • Maintain 3T3 and HepG2 cell lines and use them to determine if a compound is cytotoxic • Run MICs and MBCs on compounds received with a variety of clinical isolates • Run endotoxin assays, DNA binding assays, hemolysis assays, post… Show more Working to discover novel antibiotics from soil microbes by using proprietary technology (the “ichip”) to cultivate bacteria that were previously uncultivable in a laboratory setting. Responsible for running secondary assays on any compounds discovered. • Maintain 3T3 and HepG2 cell lines and use them to determine if a compound is cytotoxic • Run MICs and MBCs on compounds received with a variety of clinical isolates • Run endotoxin assays, DNA binding assays, hemolysis assays, post antibiotic effect assays, time kill curves, drug combination studies on compounds of interest • Isolate bacteria from terrestrial soils using in situ cultivation methods developed at NovoBiotic • Responsible for running PCR and gel electrophoresis on bacterial strains of interest for sequencing purposes • Responsible for experimental design and troubleshooting Show less



Semprus BioSciences

• United States
• Medical Device
• 1 - 100 Employee

• Research Associate

  • May 2011 - Dec 2011

  Part of a microbiology group developing bio-film assays for assessing non-fouling surface modifications on medical device technology. • Determined optimum strain-specific media for biofilm formation using high throughput screens with varying nutrient conditions • Management of sterility experiments with long-term serum storage studies • Responsible for data analysis and presentation at weekly meetings Part of a microbiology group developing bio-film assays for assessing non-fouling surface modifications on medical device technology. • Determined optimum strain-specific media for biofilm formation using high throughput screens with varying nutrient conditions • Management of sterility experiments with long-term serum storage studies • Responsible for data analysis and presentation at weekly meetings



Tetraphase Pharmaceuticals

• United States
• Biotechnology Research
• 1 - 100 Employee

• Research Associate

  • Jun 2009 - Dec 2010

  Member of a microbiology team supporting discovery, preclinical and development activities. • Responsible for regular susceptibility testing of research compounds to support drug development and IND filings. Developed and performed robust bactericidal and combination study assays for incorporation into IND filings • Performed Minimum Inhibitory Concentration (MIC) Assays, Resistance Frequency Assays, Time Kill Assays • Management of clinical isolate collection and pathogen… Show more Member of a microbiology team supporting discovery, preclinical and development activities. • Responsible for regular susceptibility testing of research compounds to support drug development and IND filings. Developed and performed robust bactericidal and combination study assays for incorporation into IND filings • Performed Minimum Inhibitory Concentration (MIC) Assays, Resistance Frequency Assays, Time Kill Assays • Management of clinical isolate collection and pathogen identification using API system • Management of compound collection • General laboratory support including media and solution preparation, waste disposal Show less Member of a microbiology team supporting discovery, preclinical and development activities. • Responsible for regular susceptibility testing of research compounds to support drug development and IND filings. Developed and performed robust bactericidal and combination study assays for incorporation into IND filings • Performed Minimum Inhibitory Concentration (MIC) Assays, Resistance Frequency Assays, Time Kill Assays • Management of clinical isolate collection and pathogen… Show more Member of a microbiology team supporting discovery, preclinical and development activities. • Responsible for regular susceptibility testing of research compounds to support drug development and IND filings. Developed and performed robust bactericidal and combination study assays for incorporation into IND filings • Performed Minimum Inhibitory Concentration (MIC) Assays, Resistance Frequency Assays, Time Kill Assays • Management of clinical isolate collection and pathogen identification using API system • Management of compound collection • General laboratory support including media and solution preparation, waste disposal Show less



Boston University

• United States
• Higher Education
• 700 & Above Employee

• Marine Biology Research Assistant

  • May 2008 - May 2009

  Research Topic: Resilience of the Coral Species Pocillopora damicornis to Damage by Lesioning. Husbandry of coral reef tanks. Lesioning coral fragments and sequential photography. Image analysis with ImageJ, Microsoft Excel, and Access.

• Forest Ecology Research Assistant

  • Oct 2005 - May 2009

  Research Topic: The Flow of Organic and Inorganic Nitrogen on an Elevation Gradient. Collection and analysis of soil samples from different elevations on Mt. Eisenhower. Incubation at different temperatures to simulate elevation gradients. Lachat analysis and OPA fluorometry to determine organic and inorganic nitrogen.