Casey O'Connor

Associate Scientist II at Asimov
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Contact Information
us****@****om
(386) 825-5501
Location
Toms River, New Jersey, United States, JE

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Associate Scientist II
      • Aug 2023 - Present

      Boston, Massachusetts, United States

    • Associate Scientist, Cell Line Development
      • Apr 2022 - Present

      Cambridge, Massachusetts, United States

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Cell Line Development Scientist
      • Aug 2021 - Dec 2021

      New Brunswick, New Jersey, United States

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Upstream Process Scientist III
      • Sep 2020 - Aug 2021

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Associate Scientist, Gene Therapy Upstream Development
      • Jul 2019 - Sep 2020

      Morrisville, North Carolina Develop perfusion mammalian cell culture processes at both bench-scale and pilot-scale for the production of rAAV for gene therapy medicines Set-up, operate, and break-down glass 2 L vessels, 20-50 L rocker SUBs, and 50-250 L SUBs Assists with the scale-up and technical transfer of cell culture processes to GMP manufacturing Maintain an ongoing seed train from vial thaw to termination to ensure cells are available for all experiments Analyze cell culture health with cell counting… Show more Develop perfusion mammalian cell culture processes at both bench-scale and pilot-scale for the production of rAAV for gene therapy medicines Set-up, operate, and break-down glass 2 L vessels, 20-50 L rocker SUBs, and 50-250 L SUBs Assists with the scale-up and technical transfer of cell culture processes to GMP manufacturing Maintain an ongoing seed train from vial thaw to termination to ensure cells are available for all experiments Analyze cell culture health with cell counting and measuring pH, gas concentrations, and metabolite concentrations Prepare samples for analysis utilizing centrifugation and filtration Document all data and experimental designs using LabWare LIMS and eLN Analyze and visualize data using statistical analysis software such as JMP and Spotfire Prepare and review technical documents such as development reports and SOPs Developed best practices guidelines for eLN writing that were used across all gene therapy Pfizer sitesPrepare large volumes of media and solutions for cell culture processes Show less

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Associate
      • Aug 2018 - Jun 2019

      Raleigh-Durham, North Carolina Area Assist in running small batch and continuous fermentations for optimization of process conditions before process scale-up to 40L fermenter Assist in running 40L continuous fermentations after conditions have been optimized on a 2L scale Oversee shake flask development and media preparation for each week's fermentations Collect data on fermentation samples to determine the optimal conditions of cell growth and make adjustments as needed Enter, analyze, and present data to the… Show more Assist in running small batch and continuous fermentations for optimization of process conditions before process scale-up to 40L fermenter Assist in running 40L continuous fermentations after conditions have been optimized on a 2L scale Oversee shake flask development and media preparation for each week's fermentations Collect data on fermentation samples to determine the optimal conditions of cell growth and make adjustments as needed Enter, analyze, and present data to the research and development team

    • Senior Research Associate
      • Aug 2018 - Jun 2019

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • Lab Assistant
      • Sep 2016 - May 2018

      RTP As a Lab Assistant I performed all of the duties I performed as an intern as well as more administrative work such as keeping the schedule up to date. I also coordinated the Science-on-the-Go program which allowed employees to take advantage of our curriculum outside of the lab.

    • Community Lab Intern
      • May 2016 - Aug 2016

      Raleigh-Durham, North Carolina Area I was responsible for the cleanliness, organization, and stock of the entire laboratory. I prepped for all of the educational summer programs that included advanced molecular biology techniques. I also wrote and tested the SOPs for the programs. I helped teach the curriculum for our summer programs and demonstrated lab techniques.

Education

  • North Carolina State University
    Bachelor of Science (B.S.), Microbiology, General
    2014 - 2018
  • Toms River High School South
    2010 - 2014

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